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Biology and Biochemistry
India
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
48983
World Ranking
7197
National Ranking
27

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in India Leader Award
  • 2022 - Research.com Biology and Biochemistry in India Leader Award

Overview

Srinivasa M. Srinivasula is affiliated with the Indian Institute of Science Education and Research, Thiruvananthapuram in India. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a total of 32 publications in these areas.

Their work spans several subfields including molecular biology, biomedical engineering, cell biology, physiology, and biophysics. This multidisciplinary approach supports investigations into complex biological processes and molecular mechanisms.

The scientist's main research topics include:

  • Cellular transport and secretion
  • Autophagy in disease and therapy
  • Advanced fluorescence microscopy techniques
  • Parkinson's disease mechanisms and treatments
  • Advanced biosensing and bioanalysis techniques
  • Nanoplatforms for cancer theranostics
  • RNA interference and gene delivery

Recent papers authored or co-authored by Srinivasa M. Srinivasula highlight a range of topics across molecular and cellular biology. Selected publications include:

  • Vanadium pentoxide nanoparticle mediated perturbations in cellular redox balance and the paradigm of autophagy to apoptosis, 2020, Free Radical Biology and Medicine
  • Mapping the Fibril Core of the Prion Subdomain of the Mammalian CPEB3 that is Involved in Long Term Memory Retention, 2021, Journal of Molecular Biology
  • Simultaneous multiple-level magnification selective plane illumination microscopy (sMx-SPIM) imaging system, 2021, Journal of Optics
  • Naturally occurring and tumor-associated variants of RNF167 promote lysosomal exocytosis and plasma membrane resealing, 2020, Journal of Cell Science
  • Endosomal-associated RFFL facilitates mitochondrial clearance by enhancing PRKN/parkin recruitment to mitochondria, 2022, Autophagy

Frequent publication venues for this researcher include:

  • Materials Chemistry Frontiers
  • Journal of Cell Science
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Free Radical Biology and Medicine
  • Journal of Molecular Biology

Srinivasa M. Srinivasula collaborates regularly with a number of coauthors. Some of the most frequent collaborators are:

  • Nikhil Dev Narendradev
  • Rishith Ravindran
  • Anoop Kumar G. Velikkakath
  • R. N. Sharma
  • Rinsa Salahudeen Rafeeka

Best Publications

  • Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

    Peng Li;Deepak Nijhawan;Imawati Budihardjo;Srinivasa M Srinivasula

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases

    Quinn L. Deveraux;Natalie Roy;Henning R. Stennicke;Todd Van Arsdale

  • Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

    Jia-Lun Wang;Dongxiang Liu;Zhi-Jia Zhang;Simei Shan

  • Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization

    Srinivasa M. Srinivasula;Manzoor Ahmad;Teresa Fernandes-Alnemri;Emad S. Alnemri

  • A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

    Srinivasa M. Srinivasula;Ramesh Hegde;Ayman Saleh;Pinaki Datta

  • Negative regulation of the Apaf-1 apoptosome by Hsp70.

    Ayman Saleh;Srinivasa M. Srinivasula;Levent Balkir;Paul D. Robbins

  • In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

    Teresa Fernandes-Alnemri;Robert C. Armstrong;Joseph Krebs;Srinivasa M. Srinivasula

  • Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction

    Ramesh Hegde;Srinivasa M. Srinivasula;ZhiJia Zhang;Richard Wassell

  • Mechanism of XIAP-Mediated Inhibition of Caspase-9

    Eric N Shiozaki;Jijie Chai;Daniel J Rigotti;Stefan J Riedl

  • Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].

    Chuan-Jin Wu;Dietrich B Conze;Tao Li;Srinivasa M Srinivasula

  • Structural Basis of Caspase-7 Inhibition by XIAP

    Jijie Chai;Eric Shiozaki;Srinivasa M. Srinivasula;Qi Wu

  • Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL

    Marion MacFarlane;Manzoor Ahmad;Srinivasa M. Srinivasula;Teresa Fernandes-Alnemri

  • Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90

    Pramod Pandey;Ayman Saleh;Atsuko Nakazawa;Shailendra Kumar

  • Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

    Srinivasa M. Srinivasula;Manzoor Ahmad;Teresa Fernandes-Alnemri;Gerald Litwack

  • Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation.

    Ayman Saleh;Srinivasa M. Srinivasula;Samir Acharya;Richard Fishel

  • The PYRIN-CARD protein ASC is an activating adaptor for caspase-1.

    Srinivasa M. Srinivasula;Jean Luc Poyet;Marjaneh Razmara;Pinaki Datta

  • Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria.

    Yin Guo;Srinivasa M. Srinivasula;Anne Druilhe;Teresa Fernandes-Alnemri

  • IAPs: What's in a Name?

    Srinivasa M. Srinivasula;Jonathan D. Ashwell

  • Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

    Shawn B. Bratton;Gail Walker;Srinivasa M. Srinivasula;Xiao Ming Sun

Frequent Co-Authors

Emad S. Alnemri
Emad S. Alnemri Thomas Jefferson University
Teresa Fernandes-Alnemri
Teresa Fernandes-Alnemri Thomas Jefferson University
Yigong Shi
Yigong Shi Westlake University
Gerald Litwack
Gerald Litwack Texas A&M Health Science Center
Jijie Chai
Jijie Chai Westlake University
Cesare Peschle
Cesare Peschle Istituto Superiore di Sanità
Ziwei Huang
Ziwei Huang University of California, San Diego
Adrian C. Newland
Adrian C. Newland Queen Mary University of London
Kevin J. Tomaselli
Kevin J. Tomaselli Pfizer (United States)
Jonathan D. Ashwell
Jonathan D. Ashwell National Institutes of Health

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