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Neuroscience

D-Index
42
Citations
9389
World Ranking
7557
National Ranking
3259

Overview

Iryna M. Ethell is affiliated with the University of California, Riverside in the United States. Their research primarily focuses on neuroscience and biochemistry, genetics, and molecular biology, with a strong emphasis on genetics and neurodevelopmental disorders.

The scientist has contributed extensively to studies in several subfields, including genetics, cellular and molecular neuroscience, cognitive neuroscience, molecular biology, and developmental neuroscience.

The main topics of their research include:

  • Genetics and Neurodevelopmental Disorders
  • Autism Spectrum Disorder Research
  • Axon Guidance and Neuronal Signaling
  • Neurogenesis and neuroplasticity mechanisms
  • Congenital heart defects research
  • Neuroscience and Neuropharmacology Research
  • Neuroscience and Neural Engineering

Iryna M. Ethell has published research in a variety of scientific venues, frequently appearing in:

  • Neurobiology of Disease
  • Journal of Neuroscience
  • Journal of Medicinal Chemistry
  • ASN NEURO
  • Journal of the Endocrine Society

Key recent papers include:

  • Cortical interneurons in autism, 2021, Nature Neuroscience
  • Multielectrode array analysis of EEG biomarkers in a mouse model of Fragile X Syndrome, 2020, Neurobiology of Disease
  • Acute pharmacological inhibition of matrix metalloproteinase-9 activity during development restores perineuronal net formation and normalizes auditory processing in Fmr1 KO mice, 2020, Journal of Neurochemistry
  • Neural Correlates of Auditory Hypersensitivity in Fragile X Syndrome, 2021, Frontiers in Psychiatry
  • Astrocytic Ephrin-B1 Controls Excitatory-Inhibitory Balance in Developing Hippocampus, 2020, Journal of Neuroscience

Frequent co-authors include:

  • Khaleel A. Razak
  • Devin K. Binder
  • Anna Kulinich
  • Jonathan W. Lovelace
  • Maija L. Castrén

Best Publications

  • Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD.

    Hong Gang Wang;Nuzhat Pathan;Iryna M. Ethell;Stanislaw Krajewski

  • Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model

    Tina Bilousova;Lorraine Dansie;Michelle Ngo;Jennifer Aye

  • Molecular mechanisms of dendritic spine development and remodeling

    Iryna M. Ethell;Elena B. Pasquale

  • Matrix metalloproteinases in brain development and remodeling: synaptic functions and targets.

    Iryna M. Ethell;Douglas W. Ethell

  • EphB/syndecan-2 signaling in dendritic spine morphogenesis.

    Iryna M. Ethell;Fumitoshi Irie;Matthew S. Kalo;John R. Couchman

  • Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus

    Mark Henkemeyer;Olga S. Itkis;Michelle Ngo;Peter W. Hickmott

  • Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons.

    Iryna M. Ethell;Yu Yamaguchi

  • GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking.

    Casper C Hoogenraad;Aaron D Milstein;Iryna M Ethell;Mark Henkemeyer

  • Open-label add-on treatment trial of minocycline in fragile X syndrome

    Carlo Paribello;Leeping Tao;Anthony Folino;Elizabeth Berry-Kravis

  • Integrins Control Dendritic Spine Plasticity in Hippocampal Neurons through NMDA Receptor and Ca2+/Calmodulin-Dependent Protein Kinase II-Mediated Actin Reorganization

    Yang Shi;Iryna M. Ethell

  • A delicate balance: role of MMP-9 in brain development and pathophysiology of neurodevelopmental disorders

    Sarah M. Reinhard;Khaleel Razak;Iryna M. Ethell

  • Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity.

    Yang Shi;Crystal G. Pontrello;Kathryn A. DeFea;Louis F. Reichardt

  • Genetic Reduction of Matrix Metalloproteinase-9 Promotes Formation of Perineuronal Nets Around Parvalbumin-Expressing Interneurons and Normalizes Auditory Cortex Responses in Developing Fmr1 Knock-Out Mice.

    Teresa H Wen;Sonia Afroz;Sarah M Reinhard;Arnold R Palacios

  • Cortical interneurons in autism.

    Anis Contractor;Iryna M Ethell;Carlos Portera-Cailliau

  • The Perineuronal 'Safety' Net? Perineuronal Net Abnormalities in Neurological Disorders.

    Teresa H. Wen;Devin K. Binder;Iryna M. Ethell;Khaleel A. Razak

  • GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii

    Clément N. David;Elma S. Frias;Jenny I. Szu;Philip A. Vieira

  • Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile x syndrome in a mouse model

    Harpreet Sidhu;Lorraine E. Dansie;Peter W. Hickmott;Douglas W. Ethell

  • Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome.

    Jonathan W. Lovelace;Iryna M. Ethell;Devin K. Binder;Khaleel A. Razak

  • Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines

    Iryna M. Ethell;Kazuki Hagihara;Yoshiaki Miura;Fumitoshi Irie

  • Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning

    Crystal G. Pontrello;Min-Yu Sun;Alice Lin;Todd A. Fiacco

  • A Rose by Any Other Name? The Potential Consequences of Microglial Heterogeneity During CNS Health and Disease

    Monica J. Carson;Tina V. Bilousova;Shweta S. Puntambekar;Benoit Melchior

  • EphB Receptors Regulate Dendritic Spine Morphogenesis through the Recruitment/Phosphorylation of Focal Adhesion Kinase and RhoA Activation

    Michael L. Moeller;Yang Shi;Louis F. Reichardt;Iryna M. Ethell

Frequent Co-Authors

Devin K. Binder
Devin K. Binder University of California, Riverside
Louis F. Reichardt
Louis F. Reichardt University of California, San Francisco
Susan M. Rivera
Susan M. Rivera University of California, Davis
Robert Rosenthal
Robert Rosenthal University of California, Riverside
Antti Vaheri
Antti Vaheri University of Helsinki
Randi J Hagerman
Randi J Hagerman University of California, Davis
Morgan Sheng
Morgan Sheng Broad Institute
Piergiorgio Strata
Piergiorgio Strata University of Turin
Hans Thoenen
Hans Thoenen Max Planck Society
David L. Nelson
David L. Nelson Baylor College of Medicine

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