World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
57
Citations
11387
World Ranking
11104
National Ranking
3032

Research.com Recognitions

  • 2018 - Fellow of the Indian National Academy of Engineering (INAE)
  • 2016 - Fellow of American Physical Society (APS) Citation For the development of quantitative methods to probe membrane protein interactions and to reveal the mechanism of activation of membrane receptors

Overview

Kalina Hristova is affiliated with Johns Hopkins University in the United States. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with significant work in Molecular Biology, Cellular and Molecular Neuroscience, Cell Biology, Oncology, and Radiology, Nuclear Medicine, and Imaging.

Hristova's recent scholarly contributions include the following papers:

  • Applications and evolution of melittin, the quintessential membrane active peptide, 2021, Biochemical Pharmacology
  • Ligand bias in receptor tyrosine kinase signaling, 2020, Journal of Biological Chemistry
  • Mechanical disruption of E-cadherin complexes with epidermal growth factor receptor actuates growth factor-dependent signaling, 2022, Proceedings of the National Academy of Sciences
  • Reversible blood-brain barrier opening utilizing the membrane active peptide melittin in vitro and in vivo, 2021, Biomaterials
  • Quantifying the strength of heterointeractions among receptor tyrosine kinases from different subfamilies: Implications for cell signaling, 2020, Journal of Biological Chemistry

Frequent coauthors collaborating with Hristova include Taylor P. Light, William C. Wimley, Kelly Karl, Elena B. Pasquale, and Daniel Wirth. These collaborators have contributed to multiple publications across various research topics.

Publication venues where Hristova has frequently contributed comprise:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Nature Communications

The scientist's main research topics encompass:

  • Axon Guidance and Neuronal Signaling
  • Receptor Mechanisms and Signaling
  • Lipid Membrane Structure and Behavior
  • Fibroblast Growth Factor Research
  • HER2/EGFR in Cancer Research
  • Monoclonal and Polyclonal Antibodies Research
  • RNA Interference and Gene Delivery

Kalina Hristova has received recognition including the Fellow of the Indian National Academy of Engineering (INAE) in 2018. In 2016, they were named a Fellow of the American Physical Society (APS) with a citation for the development of quantitative methods to probe membrane protein interactions and to reveal the mechanism of activation of membrane receptors.

Best Publications

  • Antimicrobial Peptides: Successes, Challenges and Unanswered Questions

    William C. Wimley;Kalina Hristova

  • Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol).

    A.K. Kenworthy;K. Hristova;D. Needham;T.J. McIntosh

  • How membranes shape protein structure.

    Stephen H. White;Alexey S. Ladokhin;Sajith Jayasinghe;Kalina Hristova

  • Protein Folding in Membranes: Determining Energetics of Peptide-Bilayer Interactions.

    Stephen H. White;William C. Wimley;Alexey S. Ladokhin;Kalina Hristova

  • Structure, location, and lipid perturbations of melittin at the membrane interface

    Kalina Hristova;Christopher E. Dempsey;Stephen H. White

  • Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.

    Edwin Li;Kalina Hristova

  • MPEx: A tool for exploring membrane proteins

    Craig Snider;Sajith Jayasinghe;Kalina Hristova;Stephen H. White

  • Energetics, stability, and prediction of transmembrane helices

    Sajith Jayasinghe;Kalina Hristova;Stephen H White

  • Mechanism of FGF receptor dimerization and activation

    Sarvenaz Sarabipour;Kalina Hristova

  • Spontaneous Membrane-Translocating Peptides by Orthogonal High-throughput Screening

    Jessica R. Marks;Jesse Placone;Kalina Hristova;William C. Wimley

  • Folding of beta-sheet membrane proteins: a hydrophobic hexapeptide model.

    William C. Wimley;Kalina Hristova;Alexey S. Ladokhin;Loraine Silvestro

  • An amphipathic alpha-helix at a membrane interface: a structural study using a novel X-ray diffraction method.

    Kalina Hristova;William C. Wimley;Vinod K. Mishra;G.M. Anantharamiah

  • Determination of the Hydrocarbon Core Structure of Fluid Dioleoylphosphocholine (DOPC) Bilayers by X-Ray Diffraction Using Specific Bromination of the Double-Bonds: Effect of Hydration

    Kalina Hristova;Stephen H. White

  • How IGF-1 activates its receptor

    Jennifer M Kavran;Jacqueline M McCabe;Patrick O Byrne;Mary Katherine Connacher

  • MPtopo: A database of membrane protein topology

    Sajith Jayasinghe;Kalina Hristova;Stephen H. White

  • Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins

    Kalina Hristova;Michael E. Selsted;Stephen H. White

  • Transmembrane helix dimerization: beyond the search for sequence motifs

    Edwin Li;William C. Wimley;Kalina Hristova

  • Peptide-based strategies for enhanced cell uptake, transcellular transport, and circulation: Mechanisms and challenges.

    A. Komin;L.M. Russell;K.A. Hristova;P.C. Searson

  • A Look at Arginine in Membranes

    Kalina Hristova;William C. Wimley

  • Polymer-Grafted Liposomes: Physical Basis for the “Stealth” Property

    D. Needham;K. Hristova;T. J. McIntosh;M. Dewhirst

  • Measuring the energetics of membrane protein dimerization in mammalian membranes.

    Lirong Chen;Lawrence Novicky;Mikhail Merzlyakov;Tihomir Hristov

  • VEGFR-2 conformational switch in response to ligand binding.

    Sarvenaz Sarabipour;Kurt Ballmer-Hofer;Kalina Hristova

Frequent Co-Authors

William C. Wimley
William C. Wimley Tulane University
Peter C. Searson
Peter C. Searson Johns Hopkins University
Elena B. Pasquale
Elena B. Pasquale Discovery Institute
Daniel J. Leahy
Daniel J. Leahy Johns Hopkins University School of Medicine
Thomas J. McIntosh
Thomas J. McIntosh Duke University
David E. Shaw
David E. Shaw D. E. Shaw Research
Honggang Cui
Honggang Cui Johns Hopkins University
Deborah E. Leckband
Deborah E. Leckband University of Illinois at Urbana-Champaign
Robert F. Garry
Robert F. Garry Tulane University
Philip A. Cole
Philip A. Cole Brigham and Women's Hospital

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