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D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
13209
World Ranking
9277
National Ranking
4099

Overview

Jin Chen is affiliated with Vanderbilt University in the United States and has produced a significant body of research primarily in the fields of Medicine as well as Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Immunology, Cancer Research, Pulmonary and Respiratory Medicine, and Surgery.

The scientist's research topics cover areas such as Cancer, Hypoxia, and Metabolism; RNA modifications and cancer; Cancer-related molecular mechanisms; Cancer, Lipids, and Metabolism; Immunotherapy and Immune Responses; Immune cells in cancer; and Cancer Immunotherapy and Biomarkers.

Jin Chen has published in a variety of venues, with frequent contributions to:

  • SSRN Electronic Journal
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)
  • Frontiers in Oncology

Recent notable papers include:

  • Proteogenomic Characterization of Endometrial Carcinoma, 2020, Cell
  • Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer, 2020, Journal of Clinical Investigation
  • Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells, 2020, Cell Research
  • Single-cell analysis of ploidy and the transcriptome reveals functional and spatial divergency in murine megakaryopoiesis, 2021, Blood
  • STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy, 2023, Science Immunology

Jin Chen has collaborated frequently with several co-authors, including:

  • Deanna N. Edwards
  • Verra M. Ngwa
  • Yoonha Hwang
  • Wenqiang Song
  • Shan Wang

Best Publications

  • Blockade of TGF-β inhibits mammary tumor cell viability, migration, and metastases

    Rebecca S. Muraoka;Nancy Dumont;Christoph A. Ritter;Teresa C. Dugger

  • Arginine N-Methyltransferase 1 Is Required for Early Postimplantation Mouse Development, but Cells Deficient in the Enzyme Are Viable

    M R Pawlak;C A Scherer;J Chen;M J Roshon

  • Pancreatic Islet Production of Vascular Endothelial Growth Factor-A Is Essential for Islet Vascularization, Revascularization, and Function

    Marcela Brissova;Alena Shostak;Masakazu Shiota;Peter O. Wiebe

  • The ephrins and Eph receptors in angiogenesis.

    Nikki Cheng;Dana M. Brantley;Jin Chen

  • Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

    Dana M Brantley;Nikki Cheng;Erin J Thompson;Qing Lin

  • mTORC1 and mTORC2 in cancer and the tumor microenvironment

    Laura C. Kim;Rebecca S. Cook;Jin Chen

  • The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling.

    Dana M. Brantley-Sieders;Guanglei Zhuang;Donna Hicks;Wei Bin Fang

  • EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

    Dana M. Brantley-Sieders;Justin Caughron;Donna Hicks;Ambra Pozzi

  • Elevation of Receptor Tyrosine Kinase EphA2 Mediates Resistance to Trastuzumab Therapy

    Guanglei Zhuang;Dana M. Brantley-Sieders;David Vaught;Jian Yu

  • Border Control—A Membrane-Linked Interactome of Arabidopsis

    Alexander M. Jones;Yuanhu Xuan;Meng Xu;Rui Sheng Wang

  • EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.

    Reneé C Ireton;Jin Chen

  • Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells.

    Katie A. Sharff;Wen-Xin Song;Xiaoji Luo;Ni Tang

  • Ephrin-B1 transduces signals to activate integrin-mediated migration, attachment and angiogenesis

    Uyen Huynh-Do;Cécile Vindis;Hua Liu;Douglas Pat Cerretti

  • Eph receptor tyrosine kinases in angiogenesis: from development to disease.

    Dana M Brantley-Sieders;Jin Chen

  • Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase

    D Jo;A Nashabi;C Doxsee;Q Lin

  • Production of germ-line chimeras in zebrafish by cell transplants from genetically pigmented to albino embryos.

    Shuo Lin;Wilbur Long;Jin Chen;Nancy Hopkins

  • The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus

    Alexander S Hahn;Johanna K Kaufmann;Effi Wies;Elisabeth Naschberger

  • Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression.

    Dana M. Brantley-Sieders;Wei Bin Fang;Donna J. Hicks;Guanglei Zhuang

  • Ephrin-A1 facilitates mammary tumor metastasis through an angiogenesis-dependent mechanism mediated by EphA receptor and vascular endothelial growth factor in mice.

    Dana M. Brantley-Sieders;Wei Bin Fang;Yoonha Hwang;Donna Hicks

  • A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.

    Wei Bin Fang;Dana M Brantley-Sieders;Monica A Parker;Alastair D Reith;Alastair D Reith

Frequent Co-Authors

Daniel M. Fleetwood
Daniel M. Fleetwood Vanderbilt University
Mark Boothby
Mark Boothby Vanderbilt University Medical Center
Ronald D. Schrimpf
Ronald D. Schrimpf Vanderbilt University
Lois E. H. Smith
Lois E. H. Smith Boston Children's Hospital
James S. Speck
James S. Speck University of California, Santa Barbara
Sokrates T. Pantelides
Sokrates T. Pantelides Vanderbilt University
Steven A. Ringel
Steven A. Ringel The Ohio State University
Aaron R. Arehart
Aaron R. Arehart The Ohio State University
Albert B. Reynolds
Albert B. Reynolds Vanderbilt University

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