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Overview

Ariela Benigni is affiliated with the Mario Negri Institute for Pharmacological Research in Italy. They have contributed extensively to the medical research community, particularly within the fields of immunology, nephrology, molecular biology, infectious diseases, and hematology.

Their research spans a broad range of specialized topics, including:

  • Complement system in diseases
  • Renal diseases and glomerulopathies
  • COVID-19 clinical research studies
  • SARS-CoV-2 and COVID-19 research
  • Renal and related cancers
  • Platelet disorders and treatments
  • Long-term effects of COVID-19

Ariela Benigni has published in multiple venues, with frequent contributions appearing in:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Frontiers in Immunology
  • The Nephron journals
  • International Journal of Molecular Sciences
  • Scientific Reports

Their notable recent papers include the following:

  • Immunity, endothelial injury and complement-induced coagulopathy in COVID-19, 2020, published in Nature Reviews Nephrology
  • The case of complement activation in COVID-19 multiorgan impact, 2020, published in Kidney International
  • Should COVID-19 Concern Nephrologists? Why and to What Extent? The Emerging Impasse of Angiotensin Blockade, 2020, published in The Nephron journals
  • Data Sharing Under the General Data Protection Regulation, 2021, published in Hypertension
  • SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Platelet Aggregation, 2022, published in Frontiers in Immunology

Their collaborative network includes frequent co-authors such as:

  • Giuseppe Remuzzi
  • Daniela Corna
  • Luca Perico
  • Carla Zoja
  • Monica Locatelli

Ariela Benigni's work focuses on integrating knowledge from immunology and nephrology to address disease mechanisms, particularly those related to the immune complement system and kidney pathology. Their research also investigates the clinical impact of COVID-19, including complement activation and microvascular injury related to SARS-CoV-2 infection.

Best Publications

  • Mesenchymal Stem Cells Are Renotropic, Helping to Repair the Kidney and Improve Function in Acute Renal Failure

    Marina Morigi;Barbara Imberti;Carla Zoja;Daniela Corna

  • Understanding the nature of renal disease progression

    Giuseppe Remuzzi;Piero Ruggenenti;Ariela Benigni

  • Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes

    Giuseppe Remuzzi;Ariela Benigni;Andrea Remuzzi

  • Angiotensin II revisited: new roles in inflammation, immunology and aging

    Ariela Benigni;Paola Cassis;Giuseppe Remuzzi

  • Immunity, endothelial injury and complement-induced coagulopathy in COVID-19.

    Luca Perico;Ariela Benigni;Federica Casiraghi;Lisa F.P. Ng;Lisa F.P. Ng

  • Disruption of the Ang II type 1 receptor promotes longevity in mice

    Ariela Benigni;Daniela Corna;Carla Zoja;Aurelio Sonzogni

  • Human Bone Marrow Mesenchymal Stem Cells Accelerate Recovery of Acute Renal Injury and Prolong Survival in Mice

    Marina Morigi;Martino Introna;Barbara Imberti;Daniela Corna

  • Cyclosporin-induced endothelial cell injury

    C Zoja;L Furci;F Ghilardi;P Zilio

  • Transfer of growth factor receptor mRNA via exosomes unravels the regenerative effect of mesenchymal stem cells.

    Susanna Tomasoni;Lorena Longaretti;Cinzia Rota;Marina Morigi

  • Sirtuin 3–dependent mitochondrial dynamic improvements protect against acute kidney injury

    Marina Morigi;Luca Perico;Cinzia Rota;Lorena Longaretti

  • MicroRNAs in kidney physiology and disease

    Piera Trionfini;Ariela Benigni;Giuseppe Remuzzi

  • Should COVID-19 Concern Nephrologists? Why and to What Extent? The Emerging Impasse of Angiotensin Blockade.

    Luca Perico;Ariela Benigni;Giuseppe Remuzzi

  • Anti-Phospholipase A2 Receptor Antibody Titer Predicts Post-Rituximab Outcome of Membranous Nephropathy

    Piero Ruggenenti;Hanna Debiec;Hanna Debiec;Barbara Ruggiero;Antonietta Chianca

  • Insulin-Like Growth Factor-1 Sustains Stem Cell–Mediated Renal Repair

    Barbara Imberti;Marina Morigi;Susanna Tomasoni;Cinzia Rota

  • Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.

    Ariela Benigni;Gina Gregorini;Tiziana Frusca;Chiara Chiabrando

  • Recommendations for Biomarker Identification and Qualification in Clinical Proteomics

    Harald Mischak;Guenter Allmaier;Rolf Apweiler;Teresa Attwood

  • Proximal tubular cell synthesis and secretion of endothelin-1 on challenge with albumin and other proteins

    Carla Zoja;Carla Zoja;Marina Morigi;Marina Morigi;Marina Figliuzzi;Marina Figliuzzi;Isabella Bruzzi;Isabella Bruzzi

  • Sirtuins in Renal Health and Disease

    Marina Morigi;Luca Perico;Ariela Benigni

  • A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression.

    Ariela Benigni;Carla Zoja;Daniela Corna;Silvia Orisio

  • The case of complement activation in COVID-19 multiorgan impact.

    Marina Noris;Ariela Benigni;Giuseppe Remuzzi

Frequent Co-Authors

Giuseppe Remuzzi
Giuseppe Remuzzi Mario Negri Institute for Pharmacological Research
Carla Zoja
Carla Zoja Mario Negri Institute for Pharmacological Research
Marina Noris
Marina Noris Mario Negri Institute for Pharmacological Research
Norberto Perico
Norberto Perico Mario Negri Institute for Pharmacological Research
Andrea Remuzzi
Andrea Remuzzi University of Bergamo
Piero Ruggenenti
Piero Ruggenenti Mario Negri Institute for Pharmacological Research
Pierre Ronco
Pierre Ronco Sorbonne University
Roberto Fanelli
Roberto Fanelli Mario Negri Institute for Pharmacological Research
Martino Introna
Martino Introna Mario Negri Institute for Pharmacological Research
Mauro Giacca
Mauro Giacca King's College London

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