D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 68 Citations 20,671 143 World Ranking 4871 National Ranking 2393

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Biochemistry

His main research concerns LDL receptor, Receptor, Molecular biology, Cell biology and Biochemistry. His LDL receptor study incorporates themes from Internalization, Apolipoprotein E, Endocytosis and Low-density lipoprotein. Immunology is closely connected to Endocrinology in his research, which is encompassed under the umbrella topic of Apolipoprotein E.

His Receptor study combines topics from a wide range of disciplines, such as Catabolism, VLDL receptor and Glycoprotein. The study incorporates disciplines such as Ligand, Protein subunit, Urokinase receptor, Plasminogen activator and Cell surface receptor in addition to Molecular biology. The various areas that Dudley K. Strickland examines in his Cell biology study include P3 peptide, Low-density lipoprotein receptor gene family, Thrombospondin and Transmembrane protein.

His most cited work include:

  • Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. (1074 citations)
  • Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions (939 citations)
  • LRP: A multifunctional scavenger and signaling receptor (909 citations)

What are the main themes of his work throughout his whole career to date?

Dudley K. Strickland mainly investigates LDL receptor, Biochemistry, Receptor, Cell biology and Molecular biology. His LDL receptor research includes themes of Apolipoprotein E and Low-density lipoprotein. His work deals with themes such as VLDL receptor, Very low-density lipoprotein and Very Low-Density Lipoprotein Receptor, which intersect with Receptor.

The Cell biology study combines topics in areas such as Endocytic cycle, Endocytosis, Vascular smooth muscle and Amyloid precursor protein. His Molecular biology research is multidisciplinary, relying on both Epitope, Plasma protein binding, LDL-receptor-related protein-associated protein and Ligand. His LRP1 research incorporates elements of Plasminogen activator and Immunology.

He most often published in these fields:

  • LDL receptor (48.08%)
  • Biochemistry (36.15%)
  • Receptor (35.00%)

What were the highlights of his more recent work (between 2012-2021)?

  • LRP1 (18.85%)
  • Cell biology (33.46%)
  • LDL receptor (48.08%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in LRP1, Cell biology, LDL receptor, Biochemistry and Receptor. The concepts of his LRP1 study are interwoven with issues in Apolipoprotein E, Smooth muscle contraction and Immunology. His Cell biology research is multidisciplinary, incorporating perspectives in Endocytosis, Vascular smooth muscle and Internalization.

His LDL receptor research is within the category of Lipoprotein. He interconnects Neurovascular bundle and Tissue type in the investigation of issues within Biochemistry. His studies deal with areas such as In vitro, Proteases, Inflammation, Fibrin and VLDL receptor as well as Receptor.

Between 2012 and 2021, his most popular works were:

  • MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1. (70 citations)
  • Low-Density Lipoprotein Receptor–Related Protein-1 Role in the Regulation of Vascular Integrity (65 citations)
  • LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage (63 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

Dudley K. Strickland mainly focuses on LRP1, Cell biology, Immunology, LDL receptor and Vascular smooth muscle. His LRP1 research incorporates themes from Plasma protein binding, ADAMTS, Blood–brain barrier, Fibrosis and Transforming growth factor beta. His work carried out in the field of Cell biology brings together such families of science as Smooth muscle contraction, Thromboxane receptor and Platelet-derived growth factor.

His Immunology study integrates concerns from other disciplines, such as Midkine, Plasminogen activator, Tissue plasminogen activator, Pharmacology and Transplantation. His studies examine the connections between LDL receptor and genetics, as well as such issues in Thrombospondin, with regards to LDL-receptor-related protein-associated protein and Cartilage. His study on Biochemistry is mostly dedicated to connecting different topics, such as Apolipoprotein E.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.

Masayoshi Shibata;Shinya Yamada;S. Ram Kumar;Miguel Calero.
Journal of Clinical Investigation (2000)

1543 Citations

Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions

G W Rebeck;J S Reiter;D K Strickland;B T Hyman.
Neuron (1993)

1346 Citations

LRP: A multifunctional scavenger and signaling receptor

Joachim Herz;Dudley K. Strickland.
Journal of Clinical Investigation (2001)

1203 Citations

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.

D K Strickland;J D Ashcom;S Williams;W H Burgess.
Journal of Biological Chemistry (1990)

804 Citations

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

Joachim Herz;Joseph L. Goldstein;Dudley K. Strickland;Y. K. Ho.
Journal of Biological Chemistry (1991)

660 Citations

The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A

M Z Kounnas;R E Morris;M R Thompson;D J FitzGerald.
Journal of Biological Chemistry (1992)

636 Citations

Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein

Manuel Yepes;Maria Sandkvist;Elizabeth G. Moore;Thomas H. Bugge.
Journal of Clinical Investigation (2003)

627 Citations

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

Anna P. Lillis;Lauren B. Van Duyn;Joanne E. Murphy-Ullrich;Dudley K. Strickland.
Physiological Reviews (2008)

621 Citations

LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation

M Z Kounnas;R D Moir;G W Rebeck;A I Bush.
Cell (1995)

581 Citations

A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein.

S E Williams;J D Ashcom;W S Argraves;D K Strickland.
Journal of Biological Chemistry (1992)

471 Citations

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