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D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
14063
World Ranking
7925
National Ranking
3592

Overview

G. William Rebeck is affiliated with Georgetown University Medical Center in the United States. Their research primarily spans the fields of Medicine and Neuroscience with a strong focus on subfields such as Physiology, Neurology, Genetics, Pulmonary and Respiratory Medicine, and Cognitive Neuroscience.

The main topics explored in Rebeck's work include:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cancer-related cognitive impairment studies
  • Dementia and Cognitive Impairment Research
  • Glioma Diagnosis and Treatment
  • Cholesterol and Lipid Metabolism
  • Immune cells in cancer

Frequently publishing in journals such as Molecular Neurodegeneration, International Journal of Molecular Sciences, Neurobiology of Disease, Glia, and eLife, Rebeck contributes to a variety of scientific discussions across neuroscience and molecular medicine.

Recent papers authored or co-authored by Rebeck include:

  • "ApoE Lipidation as a Therapeutic Target in Alzheimer's Disease" (2020) in International Journal of Molecular Sciences
  • "APOE in the normal brain" (2020) in Neurobiology of Disease
  • "Expression and secretion of apoE isoforms in astrocytes and microglia during inflammation" (2021) in Glia
  • "APOE2 is associated with longevity independent of Alzheimer's disease" (2020) in eLife
  • "Cancer Chemotherapy Related Cognitive Impairment and the Impact of the Alzheimer's Disease Risk Factor APOE" (2020) in Cancers

Rebeck collaborates frequently with researchers including Jordy Sepulveda, Jeanne S. Mandelblatt, Christi Anne S. Ng, Raymond Scott Turner, and Sarah A. Flowers, indicating an interconnected research network within their areas of study.

Best Publications

  • Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy.

    Thomas J. Grabowski;Hyun Soon Cho;Jean Paul G. Vonsattel;G. William Rebeck

  • Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator.

    Xiaoying Wang;Sun-Ryung Lee;Ken Arai;Seong-Ryong Lee

  • Multiple, diverse senile plaque–associated proteins are ligands of an apolipoprotein e receptor, the α2-macroglobulin receptor/low-density-lipoprotein receptor—related protein

    G. William Rebeck;Steven D. Harr;Bradley T. Hyman;Dudley K. Strickland

  • Clinical manifestations of cerebral amyloid angiopathy-related inflammation.

    Jessica A. Eng;Matthew P. Frosch;Kyungchan Choi;G. William Rebeck

  • Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.

    Paula G. Ulery;Jeanette Beers;Irina Mikhailenko;Rudolph E. Tanzi

  • APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease

    Katherine L. Youmans;Leon M. Tai;Evelyn Nwabuisi-Heath;Lisa Jungbauer

  • Pathogenic Effects of D23N Iowa Mutant Amyloid β-Protein

    William E. Van Nostrand;Jerry P. Melchor;Hyun Soon Cho;Steven M. Greenberg

  • Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.

    Chiho Hirata-Fukae;Hui Fang Li;Hyang Sook Hoe;Audrey J. Gray

  • Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury

    David J. Loane;Ana Pocivavsek;Charbel E.-H. Moussa;Rachel Thompson

  • ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo

    Sonya B. Dumanis;Joseph A. Tesoriero;Lenard W. Babus;Madeline T. Nguyen

  • Interaction of Reelin with Amyloid Precursor Protein Promotes Neurite Outgrowth

    Hyang-Sook Hoe;Kea Joo Lee;Rosalind S. E. Carney;Jiyeon Lee

  • APOE genotype alters glial activation and loss of synaptic markers in mice.

    Yuangui Zhu;Evelyn Nwabuisi-Heath;Sonya B. Dumanis;Leon M. Tai

  • Induction of the Cholesterol Transporter ABCA1 in Central Nervous System Cells by Liver X Receptor Agonists Increases Secreted Aβ Levels

    Hiroaki Fukumoto;Amy Deng;Michael C. Irizarry;Michael L. Fitzgerald

  • DAB1 and Reelin Effects on Amyloid Precursor Protein and ApoE Receptor 2 Trafficking and Processing

    Hyang Sook Hoe;Tracy S. Tran;Yasuji Matsuoka;Brian W. Howell

  • Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density

    Justin T. Rogers;Ian Rusiana;Justin Trotter;Lisa Zhao

  • Demonstration by fluorescence resonance energy transfer of two sites of interaction between the low-density lipoprotein receptor-related protein and the amyloid precursor protein: role of the intracellular adapter protein Fe65.

    Ayae Kinoshita;Christa M. Whelan;Carolyn J. Smith;Irena Mikhailenko

  • Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Aβ in AD models

    Preeti J. Khandelwal;Alexander M. Herman;Hyang-Sook Hoe;G. William Rebeck

  • Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition

    Gustavo A Rodriguez;Leon M Tai;Mary Jo LaDu;G William Rebeck

  • Elevation of cystatin C in susceptible neurons in Alzheimer's disease.

    Amy Deng;Michael C. Irizarry;Roger M. Nitsch;John H. Growdon

  • The generation and function of soluble apoE receptors in the CNS

    G William Rebeck;Mary Jo LaDu;Steven Estus;Guojun Bu

Frequent Co-Authors

Bradley T. Hyman
Bradley T. Hyman Harvard University
Dudley K. Strickland
Dudley K. Strickland American Red Cross
Steven M. Greenberg
Steven M. Greenberg Harvard University
Edwin J. Weeber
Edwin J. Weeber University of South Florida
Mary Jo LaDu
Mary Jo LaDu University of Illinois at Chicago
Guojun Bu
Guojun Bu Hong Kong University of Science and Technology
John H. Growdon
John H. Growdon Harvard University
Alan I. Faden
Alan I. Faden University of Maryland, Baltimore
Rudolph E. Tanzi
Rudolph E. Tanzi Harvard University
Paul S. Aisen
Paul S. Aisen University of Southern California

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