World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
122
Citations
69163
World Ranking
3424
National Ranking
1886

Overview

John H. Growdon is affiliated with Harvard University in the United States and specializes in medical research with a strong focus on neurology. Their work predominantly covers neurological disorders, including Parkinson's disease and Alzheimer's disease, integrating fields such as genetics, physiology, and molecular biology.

Their research spans several main topics, including:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Dementia and Cognitive Impairment Research
  • Neurological disorders and treatments
  • Genetic Associations and Epidemiology
  • Balance, Gait, and Falls Prevention
  • Diet and metabolism studies

John H. Growdon has contributed to multiple publications in respected venues with recurrent publications in "Brain," where they have published three articles, as well as scientific data journals such as "Scientific Data" with two publications. Other notable venues include "Neurology," which features two of their papers, "Nature Communications," and "Nature Genetics."

Frequent collaborators include Bradley T. Hyman, Albert Y. Hung, Michael T. Hayes, Anne-Marie Wills, and Clemens R. Scherzer, each having coauthored multiple works with Growdon.

Some of their recent papers include:

  • Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study, 2020, Nature Communications
  • Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease, 2021, Nature Genetics
  • Accelerometer data collected with a minimum set of wearable sensors from subjects with Parkinson's disease, 2021, Scientific Data
  • β-Glucocerebrosidase activity in GBA -linked Parkinson disease, 2020, Neurology
  • Associations of Lower Caffeine Intake and Plasma Urate Levels with Idiopathic Parkinson's Disease in the Harvard Biomarkers Study, 2020, Journal of Parkinson s Disease

John H. Growdon's expertise converges on the intersection of neurodegenerative disease mechanisms and treatment development. Their work in Parkinson's disease mechanisms includes investigations into genetic factors and biomarker studies, while Alzheimer's research addresses risk factors and disease progression. Their involvement in dementia and cognitive impairment research incorporates an understanding of neurological function and epidemiology. The research also extends into related topics such as balance and gait, which contribute to fall prevention strategies in affected populations.

The scientist has published extensively in medically oriented journals, emphasizing clinical neurology and physiological studies related to neurodegeneration and metabolic influences on neurological disease.

Best Publications

  • A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study

    Mary Sano;Christopher Ernesto;Ronald G. Thomas;Melville R. Klauber

  • Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

    Arriagada Pv;Growdon Jh;Hedley-Whyte Et;Hyman Bt

  • Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) Report of the NINDS-SPSP International Workshop*

    I. Litvan;Y. Agid;D. Calne;G. Campbell

  • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

    Adam C. Naj;Gyungah Jun;Gary W. Beecham;Li-San Wang

  • Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease

    Teresa Gómez-Isla;Joseph L. Price;Daniel W. McKeel;John C. Morris

  • Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

    Teresa Gómez-Isla;Richard Hollister;Howard West;Stina Mui

  • Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease

    W. Koller;C. W. Olanow;R. Rodnitzky;J. S. Fink

  • The genetic defect causing familial Alzheimer's disease maps on chromosome 21

    Peter H. St George-Hyslop;Rudolph E. Tanzi;Ronald J. Polinsky;Jonathan L. Haines

  • The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals

    Bradford C. Dickerson;Akram Bakkour;David H. Salat;Eric Feczko

  • Release of Alzheimer Amyloid Precursor Derivatives Stimulated by Activation of Muscarinic Acetylcholine Receptors

    Roger M. Nitsch;Barbara E. Slack;Richard J. Wurtman;John H. Growdon

  • A neural dissociation within language: Evidence that the mental dictionary is part of declarative memory, and that grammatical rules are processed by the procedural system

    Michael T. Ullman;Suzanne Corkin;Marie Coppola;Gregory Hickok

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease'

    Peter Davies;Judith Resnick;Burton Resnick;Sid Gilman

  • Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

    M. Ingelsson;H. Fukumoto;K. L. Newell;J. H. Growdon

  • Monitoring Motor Fluctuations in Patients With Parkinson's Disease Using Wearable Sensors

    S. Patel;K. Lorincz;R. Hughes;N. Huggins

  • DLB and PDD boundary issues: Diagnosis, treatment, molecular pathology, and biomarkers

    C. F. Lippa;J. E. Duda;M. Grossman;H. I. Hurtig

  • Evidence for a membrane defect in Alzheimer disease brain.

    Roger M. Nitsch;Jan K. Blusztajn;Anastassios G. Pittas;Barbara E. Slack

  • Validating novel tau positron emission tomography tracer [F‐18]‐AV‐1451 (T807) on postmortem brain tissue

    Marta Marquié;Marta Marquié;Marc D. Normandin;Charles R. Vanderburg;Isabel M. Costantino

  • Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

    Vivianna M. Van Deerlin;Patrick M A Sleiman;Maria Martinez-Lage;Maria Martinez-Lage;Alice Chen-Plotkin

  • Head injury and the risk of AD in the MIRAGE study

    Z. Guo;L. A. Cupples;A. Kurz;S. H. Auerbach

Frequent Co-Authors

Bradley T. Hyman
Bradley T. Hyman Harvard University
Joseph J. Locascio
Joseph J. Locascio Harvard University
Matthew P. Frosch
Matthew P. Frosch Harvard University
Keith A. Johnson
Keith A. Johnson Harvard University
Lindsay A. Farrer
Lindsay A. Farrer Boston University
Peter St George-Hyslop
Peter St George-Hyslop Columbia University
Richard H. Myers
Richard H. Myers Boston University
Rudolph E. Tanzi
Rudolph E. Tanzi Harvard University

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