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Medicine

D-Index
82
Citations
27354
World Ranking
16016
National Ranking
1470

Overview

James A. R. Nicoll is affiliated with the University of Southampton in the United Kingdom. Their research primarily focuses on Medicine and Neuroscience, with notable contributions in the subfields of Neurology, Physiology, Molecular Biology, Genetics, and Psychiatry and Mental Health.

Nicoll's main topics of research include:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Glioma Diagnosis and Treatment
  • Dementia and Cognitive Impairment Research
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Parkinson's Disease Mechanisms and Treatments
  • Immune cells in cancer

They have published extensively in venues such as:

  • Alzheimer s & Dementia
  • Neuropathology and Applied Neurobiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain
  • Acta Neuropathologica

Frequent collaborators include Delphine Boche, David S. Chatelet, Roxana O. Carare, Thomas S. Jacques, and Diego Gómez-Nicola.

Some of Nicoll's recent papers are:

  • "Amyloid-related imaging abnormalities (ARIA): radiological, biological and clinical characteristics," 2023, Brain
  • "The spatiotemporal dynamics of microglia across the human lifespan," 2022, Developmental Cell
  • "Microglial morphology in Alzheimer's disease and after Aβ immunotherapy," 2021, Scientific Reports
  • "Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA)," 2020, Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
  • "Neuroinflammation in dementia with Lewy bodies: a human post-mortem study," 2020, Translational Psychiatry

Best Publications

  • Microglia in neurodegenerative disease

    V. Hugh Perry;James A. R. Nicoll;Clive Holmes

  • Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

    Clive Holmes;Clive Holmes;Delphine Boche;David Wilkinson;David Wilkinson;Ghasem Yadegarfar;Ghasem Yadegarfar

  • Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

    James A.R. Nicoll;James A.R. Nicoll;David Wilkinson;David Wilkinson;Clive Holmes;Clive Holmes;Phil Steart

  • Review: Activation patterns of microglia and their identification in the human brain

    D. Boche;V. H. Perry;J. A. R. Nicoll;J. A. R. Nicoll

  • Association of apolipoprotein E polymorphism with outcome after head injury

    Graham M Teasdale;James A R Nicoll;Gordon Murray;Matilda Fiddes

  • Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma.

    R Rampling;G Cruickshank;V Papanastassiou;J Nicoll

  • Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology

    R. O. Carare;M. Bernardes-Silva;T. A. Newman;A. M. Page

  • Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury.

    James A.R. Nicoll;Gareth W. Roberts;David I. Graham

  • Association of interleukin-1 gene polymorphisms with Alzheimer's disease.

    James A. R. Nicoll;Robert E. Mrak;Robert E. Mrak;David I. Graham;Janice Stewart

  • Recent advances in neurotrauma.

    D. I. Graham;T. K. McIntosh;W. L. Maxwell;J. A. R. Nicoll

  • The potential for efficacy of the modified (ICP 34.5(-)) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study.

    V Papanastassiou;R Rampling;M Fraser;R Petty

  • Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy

    Cheryl A. Hawkes;Wolfgang Härtig;Johannes Kacza;Reinhard Schliebs

  • Abeta species removal after abeta42 immunization.

    James A. R. Nicoll;James A. R. Nicoll;Edward Barton;Delphine Boche;James William Neal

  • Consequence of Aβ immunization on the vasculature of human Alzheimer's disease brain

    D. Boche;E. Zotova;R. O. Weller;S. Love

  • Neuronal cytoskeletal changes are an early consequence of repetitive head injury.

    J. F. Geddes;G. H. Vowles;J. A. R. Nicoll;T. Révész

  • High frequency of apolipoprotein E epsilon 2 allele in hemorrhage due to cerebral amyloid angiopathy.

    James A. R. Nicoll;Claire Burnett;Seth Love;David I. Graham

  • Microvasculature changes and cerebral amyloid angiopathy in Alzheimer’s disease and their potential impact on therapy

    Roy O. Weller;Delphine Boche;James A. R. Nicoll

  • The nature, distribution and causes of traumatic brain injury.

    D.I. Graham;J. Hume Adams;J.A.R. Nicoll;W.L. Maxwell

  • Long-term intracerebral inflammatory response after traumatic brain injury.

    S.M. Gentleman;P.D. Leclercq;L. Moyes;D.I. Graham

  • Capillary and arterial cerebral amyloid angiopathy in Alzheimer's disease: defining the perivascular route for the elimination of amyloid beta from the human brain.

    S. D. Preston;P. V. Steart;A. Wilkinson;J. A. R. Nicoll

Frequent Co-Authors

Delphine Boche
Delphine Boche University of Southampton
Clive Holmes
Clive Holmes University of Southampton
Seth Love
Seth Love University of Bristol
David I. Graham
David I. Graham University of Glasgow
Colin Smith
Colin Smith University of Edinburgh
Karen Horsburgh
Karen Horsburgh University of Edinburgh
David Wilkinson
David Wilkinson The Francis Crick Institute
James W. Ironside
James W. Ironside University of Edinburgh
Carol Brayne
Carol Brayne University of Cambridge

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