World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
44
Citations
5744
World Ranking
17008
National Ranking
4187

Biology and Biochemistry

D-Index
45
Citations
6014
World Ranking
19170
National Ranking
7825

Overview

Leonid Medved is affiliated with the University of Maryland, Baltimore in the United States. Their research primarily focuses on medicine, with specific attention to subfields such as pulmonary and respiratory medicine, molecular biology, hematology, epidemiology, and physiology.

Their work covers a range of topics including blood properties and coagulation, adipokines, inflammation, and metabolic diseases, erythrocyte function and pathophysiology, Wnt/β-catenin signaling in development and cancer, platelet disorders and treatments, cancer-related gene regulation, and proteoglycans and glycosaminoglycans research.

Leonid Medved has authored several recent scientific papers, including:

  • The Story of the Fibrin(ogen) αC-Domains: Evolution of Our View on Their Structure and Interactions (2021, Thrombosis and Haemostasis)
  • Structure and function of fibrinogen B?N-domains (2020, The Ukrainian Biochemical Journal)

Medved frequently collaborates with coauthors in their research. Notable frequent collaborators include Sergiy Yakovlev, Dudley K. Strickland, Nico Tjandra, John W. Weisel, and James M. Gruschus.

Their publications are often found in scientific journals such as:

  • Biochemistry
  • Thrombosis and Haemostasis
  • The Ukrainian Biochemical Journal
  • Thrombosis Research
  • Research and Practice in Thrombosis and Haemostasis

Medved's research contributions are primarily situated within the field of medicine, with an emphasis on understanding molecular and physiological mechanisms related to blood coagulation and inflammatory processes.

Best Publications

  • Carboxyl-terminal portions of the alpha chains of fibrinogen and fibrin. Localization by electron microscopy and the effects of isolated alpha C fragments on polymerization.

    Y I Veklich;O V Gorkun;L V Medved;W Nieuwenhuizen

  • Molecular mechanisms of initiation of fibrinolysis by fibrin.

    Leonid Medved;Willem Nieuwenhuizen

  • The Structure and Function of the αC Domains of Fibrinogen

    John W. Weisel;Leonid Medved

  • Role of the alpha C domains of fibrin in clot formation.

    Oleg V. Gorkun;Yuri I. Veklich;Leonid V. Medved;Agnes H. Henschen

  • Domains in the fibrinogen molecule.

    P.L. Privalov;L.V. Medved

  • Identification of a Novel Recognition Sequence for Integrin αMβ2 within the γ-chain of Fibrinogen

    Tatiana P. Ugarova;Dmitry A. Solovjov;Li Zhang;Dmitry I. Loukinov

  • Interaction of fibrin(ogen) with fibronectin: further characterization and localization of the fibronectin-binding site.

    Evgeny Makogonenko;Galina Tsurupa;Kenneth Ingham;Leonid Medved

  • Recommendations for nomenclature on fibrinogen and fibrin.

    L. Medved;J. W. Weisel

  • Conversion of fibrinogen to fibrin: mechanism of exposure of tPA- and plasminogen-binding sites.

    Sergei Yakovlev;Eugeny Makogonenko;Natalia Kurochkina;Willem Nieuwenhuizen

  • Crystal structure of the complex between thrombin and the central ''E'' region of fibrin

    Igor Pechik;Joel Madrazo;Michael W. Mosesson;Irene Hernandez

  • Multiple Binding Sites in Fibrinogen for Integrin αMβ2 (Mac-1)

    Valeryi K. Lishko;Nataly P. Podolnikova;Valentin P. Yakubenko;Sergiy Yakovlev

  • The Interaction of Fibulin-1 with Fibrinogen A POTENTIAL ROLE IN HEMOSTASIS AND THROMBOSIS

    Huan Tran;A. Tanaka;S. V. Litvinovich;L. V. Medved

  • Specific binding of integrin αvβ3 to the fibrinogen γ and α(E) chain C-terminal domains

    Kenji Yokoyama;Xi Ping Zhang;Leonid Medved;Yoshikazu Takada

  • Identification and characterization of novel tPA- and plasminogen-binding sites within fibrin(ogen) alpha C-domains.

    Galina Tsurupa;Leonid Medved

  • Structural organization of C‐terminal parts of fibrinogen Aα‐chains

    L.V. Medved;O.V. Gorkun;P.L. Privalov

  • Fibrinopeptides A and B release in the process of surface fibrin formation.

    Tomas Riedel;Jiri Suttnar;Eduard Brynda;Milan Houska

  • Interaction of fibrin(ogen) with the endothelial cell receptor VE-cadherin: mapping of the receptor-binding site in the NH2-terminal portions of the fibrin beta chains.

    Sergei Gorlatov;Leonid Medved

  • Structural basis for sequential cleavage of fibrinopeptides upon fibrin assembly.

    Igor Pechik;Sergiy Yakovlev;Michael W. Mosesson;Gary L. Gilliland

  • Polymerization of fibrin: direct observation and quantification of individual B:b knob-hole interactions

    Rustem I. Litvinov;Oleg V. Gorkun;Dennis K. Galanakis;Sergiy Yakovlev

  • Structure, Stability, and Interaction of the Fibrin(ogen) αC-Domains

    Galina Tsurupa;Roy R. Hantgan;Robert A. Burton;Igor Pechik

  • FACTOR XIIIA-CATALYZED CROSS-LINKING OF RECOMBINANT ALPHA C FRAGMENTS OF HUMAN FIBRINOGEN

    Yury V. Matsuka;Leonid V. Medved;Mary M. Migliorini;Kenneth C. Ingham

Frequent Co-Authors

John W. Weisel
John W. Weisel University of Pennsylvania
Michael W. Mosesson
Michael W. Mosesson American Association of State Colleges and Universities
Nico Tjandra
Nico Tjandra National Institutes of Health
Dudley K. Strickland
Dudley K. Strickland American Red Cross
Gary L. Gilliland
Gary L. Gilliland National Institute of Standards and Technology
Edward F. Plow
Edward F. Plow Cleveland Clinic Lerner College of Medicine
Andrew P. Mazar
Andrew P. Mazar Northwestern University
Konstantinos Konstantopoulos
Konstantinos Konstantopoulos Johns Hopkins University
Agnes Henschen
Agnes Henschen Max Planck Society
Laura E. Green
Laura E. Green University of Birmingham

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