World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
23100
World Ranking
4301
National Ranking
2098

Overview

Yoshikazu Takada is affiliated with the University of California, Davis in the United States. Their research spans multiple areas within medicine, particularly focusing on immunology and microbiology, with a notable emphasis on immunology and allergy, hematology, molecular biology, and oncology as subfields. The main topics in their work include cell adhesion molecules research, platelet disorders and treatments, immunotherapy and immune responses, fibroblast growth factor research, immune response and inflammation, chemokine receptors and signaling, and proteoglycans and glycosaminoglycans research.

Takada's publication record features studies in several respected scientific journals and platforms. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), where they have published nine papers, Cells with five papers, The Journal of Immunology with two papers, the International Journal of Molecular Sciences with two papers, and the Journal of Biological Chemistry with one paper.

Among their recent research publications are:

  • Soluble CD40L activates soluble and cell-surface integrin αvβ3, α5β1, and α4β1 by binding to the allosteric ligand-binding site (site 2), 2021, Journal of Biological Chemistry
  • Anti-Monomeric C-Reactive Protein Antibody Ameliorates Arthritis and Nephritis in Mice, 2021, The Journal of Immunology
  • Pro-Inflammatory Chemokines CCL5, CXCL12, and CX3CL1 Bind to and Activate Platelet Integrin αIIbβ3 in an Allosteric Manner, 2022, Cells
  • The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand, 2023, Life Science Alliance
  • Histological and Immunohistochemical Features of Normal Histiocytes and Langerhans Cells, and Histiocytic Sarcomas in Four-Toed Hedgehogs (Atelerix albiventris), 2020, Journal of Comparative Pathology

Takada's collaborative network includes frequent co-authors such as Yoko K. Takada, Masaaki Fujita, Chun-Yi Wu, and Michiko Shimoda.

Best Publications

  • VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

    Mariano J. Elices;Laurelee Osborn;Yoshikazu Takada;Carol Crouse

  • Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site.

    Gabriele Weitz-Schmidt;Karl Welzenbach;Volker Brinkmann;Tetsji Kamata

  • Fibulin-5/DANCE is essential for elastogenesis in vivo

    Tomoyuki Nakamura;Pilar Ruiz Lozano;Yasuhiro Ikeda;Yoshitaka Iwanaga

  • In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells

    Bosco M.C. Chan;Nariaki Matsuura;Yoshikazu Takada;Bruce R. Zetter

  • Characterization of the cell surface heterodimer VLA-4 and related peptides.

    M. E. Hemler;C. Huang;Yoshikazu Takada;L. Schwarz

  • The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

    Yoshikazu Takada;M. E. Hemler

  • Structure of the integrin VLA-4 and its cell-cell and cell-matrix adhesion functions

    Martin E. Hemler;Mariano J. Elices;Christina Parker;Yoshikazu Takada

  • Inhibition of tissue factor signaling suppresses tumor growth

    Henri H. Versteeg;Florence Schaffner;Marjolein Kerver;Helle H. Petersen

  • The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.

    Yoshikazu Takada;M. J. Elices;C. Crouse;M. E. Hemler

  • Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common β1 chain

    Alfonso Luque;Manuel Gómez;Wilma Puzon;Yoshikazu Takada

  • Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells.

    Shuang Huang;Tetsuji Kamata;Yoshikazu Takada;Zaverio M. Ruggeri

  • Specific Interaction of the Recombinant Disintegrin-like Domain of MDC-15 (Metargidin, ADAM-15) with Integrin αvβ3

    Xi Ping Zhang;Tetsuji Kamata;Kenji Yokoyama;Wilma Puzon-McLaughlin

  • Fibronectin receptor structures in the VLA family of heterodimers.

    Yoshikazu Takada;Christina Huang;Martin E. Hemler

  • Distinct functions of integrin alpha and beta subunit cytoplasmic domains in cell spreading and formation of focal adhesions

    J. Ylänne;Y. Chen;T. E. O'Toole;J. C. Loftus

  • Combinatorial chemistry identifies high-affinity peptidomimetics against α4β1 integrin for in vivo tumor imaging

    Li Peng;Ruiwu Liu;Jan Marik;Xiaobing Wang

  • RGD-independent Binding of Integrin α9β1 to the ADAM-12 and -15 Disintegrin Domains Mediates Cell-Cell Interaction

    Koji Eto;Wilma Puzon-McLaughlin;Dean Sheppard;Atsuko Sehara-Fujisawa

  • Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion.

    Banu E. Symington;Yoshikazu Takada;William G. Carter

  • Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies.

    Yoshikazu Takada;Wilma Puzon

  • Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells.

    Takehiko Tarui;Lindsey A. Miles;Yoshikazu Takada

  • Extracellular matrix receptors, ECMRII and ECMRI, for collagen and fibronectin correspond to VLA-2 and VLA-3 in the VLA family of heterodimers

    Yoshikazu Takada;Elizabeth A. Wayner;William G. Carter;Martin E. Hemler

Frequent Co-Authors

Martin E. Hemler
Martin E. Hemler Harvard University
Kit S. Lam
Kit S. Lam University of California, Davis
Barbara S. Coulson
Barbara S. Coulson University of Melbourne
Emanual Michael Maverakis
Emanual Michael Maverakis University of California, Davis
Fu-Tong Liu
Fu-Tong Liu Academia Sinica
Wolfram Ruf
Wolfram Ruf Johannes Gutenberg University of Mainz
Yasuo Ikeda
Yasuo Ikeda Waseda University
Junichi Takagi
Junichi Takagi Osaka University
Martin J. Humphries
Martin J. Humphries University of Manchester
Douglas B. Cines
Douglas B. Cines University of Pennsylvania

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