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Molecular Biology

D-Index
54
Citations
11104
World Ranking
2321
National Ranking
1144

Overview

Lingeng Lu is affiliated with Yale University in the United States. Their research activity spans key areas in medicine and biochemistry, genetics and molecular biology, with notable focus on molecular biology, oncology, cancer research, immunology, and obstetrics and gynecology.

The main subjects addressed in Lingeng Lu's scholarly work include cancer-related molecular mechanisms research, cancer immunotherapy and biomarkers, cancer risks and factors, epigenetics and DNA methylation, endometrial and cervical cancer treatments, RNA modifications and cancer, and immunotherapy and immune responses.

Frequent coauthors collaborating with Lingeng Lu include:

  • Harvey A. Risch
  • Herbert Yu
  • Rui Han
  • Caroline H. Johnson
  • Sajid Khan

Lingeng Lu has published extensively in several venues, with the most common outlets being:

  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Cancer
  • International Immunopharmacology
  • BMC Cancer

Recent notable papers authored or coauthored by Lingeng Lu include:

  • "Intratumour microbiome associated with the infiltration of cytotoxic CD8+ T cells and patient survival in cutaneous melanoma" (2021, European Journal of Cancer)
  • "Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer" (2020, International Journal of Cancer)
  • "Factors affecting tumor responders and predictive biomarkers of toxicities in cancer patients treated with immune checkpoint inhibitors" (2020, International Immunopharmacology)
  • "Randomized trial of physical activity on quality of life and lung cancer biomarkers in patients with advanced stage lung cancer: a pilot study" (2021, BMC Cancer)
  • "tRFtarget: a database for transfer RNA-derived fragment targets" (2020, Nucleic Acids Research)

Lingeng Lu's work links molecular and clinical insights across cancer biology, immunotherapy, and genetic risk factors. Their ongoing contributions to oncology and molecular biology enhance understanding of cancer mechanisms, immune responses, and therapeutic biomarkers.

Best Publications

  • The imprinted H19 lncRNA antagonizes let-7 microRNAs.

    Amanda N. Kallen;Xiao-Bo Zhou;Xiao-Bo Zhou;Jie Xu;Chong Qiao;Chong Qiao

  • Type I and II Endometrial Cancers: Have They Different Risk Factors?

    Veronica Wendy Setiawan;Hannah P. Yang;Malcolm C. Pike;Malcolm C. Pike;Susan E. McCann;Susan E. McCann

  • High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-β1

    Biyun Qian;Dionyssios Katsaros;Lingeng Lu;Mario Preti

  • Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosis.

    Lingeng Lu;Dionyssios Katsaros;Irene A. Rigault de la Longrais;Olga Sochirca

  • Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

    Erica J Childs;Evelina Mocci;Daniele Campa;Daniele Campa;Paige M Bracci

  • Identification of nine new susceptibility loci for endometrial cancer

    Tracy A. O'Mara;Dylan M. Glubb;Frédéric Amant;Daniela Annibali

  • Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.

    Alison P. Klein;Brian M. Wolpin;Harvey A. Risch;Rachael Z. Stolzenberg-Solomon

  • Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation.

    L Yan;J Zhou;Y Gao;S Ghazal

  • H19 lncRNA alters DNA methylation genome wide by regulating S-adenosylhomocysteine hydrolase

    Jichun Zhou;Lihua Yang;Tianyu Zhong;Martin Mueller

  • ABO Blood Group, Helicobacter pylori Seropositivity, and Risk of Pancreatic Cancer: A Case–Control Study

    Harvey A. Risch;Herbert Yu;Lingeng Lu;Mark S. Kidd

  • Association of large noncoding RNA HOTAIR expression and its downstream intergenic CpG island methylation with survival in breast cancer

    Lingeng Lu;Guangjian Zhu;Chong Zhang;Qian Deng;Qian Deng

  • A KRAS-Variant in Ovarian Cancer Acts as a Genetic Marker of Cancer Risk

    Elena Ratner;Lingeng Lu;Marta Boeke;Rachel Barnett

  • Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II.

    Lingeng Lu;Dionyssios Katsaros;Khvaramze Shaverdashvili;Biyun Qian;Biyun Qian

  • Metformin alters DNA methylation genome-wide via the H19/SAHH axis

    T. Zhong;Y. Men;Y. Men;L. Lu;T. Geng;T. Geng

  • IGF-I in epithelial ovarian cancer and its role in disease progression.

    Jane Brokaw;Dionyssios Katsaros;Andrew Wiley;Lingeng Lu

  • Genome-Wide Association Study of Alcohol Dependence Implicates KIAA0040 on Chromosome 1q

    Lingjun Zuo;Joel Gelernter;Clarence K. Zhang;Hongyu Zhao

  • Physical activity and breast cancer survival: an epigenetic link through reduced methylation of a tumor suppressor gene L3MBTL1

    Hongmei Zeng;Melinda L. Irwin;Lingeng Lu;Harvey Risch

  • Characterization of large structural genetic mosaicism in human autosomes

    Mitchell J. Machiela;Weiyin Zhou;Joshua N. Sampson;Michael C. Dean

  • Autoinducer-2–like Activity Associated with Foods and Its Interaction with Food Additives

    Lingeng Lu;Michael E. Hume;Michael E. Hume;Suresh D. Pillai

  • ABO Blood Group and Risk of Pancreatic Cancer: A Study in Shanghai and Meta-Analysis

    Harvey A. Risch;Lingeng Lu;Jing Wang;Wei Zhang

Frequent Co-Authors

Harvey A. Risch
Harvey A. Risch Yale University
Dionyssios Katsaros
Dionyssios Katsaros University of Turin
Immaculata De Vivo
Immaculata De Vivo Harvard University
Melinda L. Irwin
Melinda L. Irwin Yale University
Jennifer A. Doherty
Jennifer A. Doherty University of Utah
Xiao-Ou Shu
Xiao-Ou Shu Vanderbilt University Medical Center
Graham G. Giles
Graham G. Giles University of Melbourne
Christine M. Friedenreich
Christine M. Friedenreich Alberta Health Services
Jolanta Lissowska
Jolanta Lissowska Maria Sklodowska-Curie National Research Institute of Oncology
Amanda B. Spurdle
Amanda B. Spurdle QIMR Berghofer Medical Research Institute

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