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Junichi Takagi

Junichi Takagi

Osaka University
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
19933
World Ranking
5594
National Ranking
361

Junichi Takagi publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Junichi Takagi sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 297 publications — 78th percentile

78% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Junichi Takagi D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Junichi Takagi sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 74 D-Index — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Junichi Takagi is affiliated with Osaka University in Japan and is an active researcher primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their scholarly output reflects significant involvement in molecular biology, infectious diseases, oncology, radiology, nuclear medicine and imaging, and immunology and allergy.

The scientist's main research topics include monoclonal and polyclonal antibodies research, SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, cell adhesion molecules research, glycosylation and glycoproteins research, axon guidance and neuronal signaling, and dental development and anomalies.

Junichi Takagi has contributed to numerous publications, several of which have been influential within their respective fields. Recent papers include:

  • Structural insights into integrin α5β1 opening by fibronectin ligand (2021), published in Science Advances
  • Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2 (2021), published in Nature Communications
  • Structural mechanism of laminin recognition by integrin (2021), published in Nature Communications
  • An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo (2022), published in Science Translational Medicine
  • Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex (2023), published in Science Immunology

Their research has appeared frequently in several academic venues, including:

  • The Journal of Biochemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Science Translational Medicine
  • Structure

Junichi Takagi has collaborated extensively with other researchers, working regularly with coauthors such as Takao Arimori, Emiko Mihara, Hiroaki Suga, Toru Okamoto, and Atsushi Hoshino. These collaborations have contributed to a diverse body of work spanning multiple disciplines within biomedical sciences.

Best Publications

  • Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling

    Junichi Takagi;Benjamin M. Petre;Thomas Walz;Timothy A. Springer

  • Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

    Tsars Xiao;Junichi Takagi;Junichi Takagi;Barry S. Coller;Jia-Huai Wang

  • Conformational Regulation of Integrin Structure and Function

    Motomu Shimaoka;Junichi Takagi;Timothy A Springer

  • Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation

    Motomu Shimaoka;Tsan Sam Xiao;Jin Huan Liu;Yuting Yang

  • Integrin activation and structural rearrangement.

    Junichi Takagi;Timothy A. Springer

  • Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

    Takashi Seino;Shintaro Kawasaki;Mariko Shimokawa;Hiroki Tamagawa

  • Ligand-binding specificities of laminin-binding integrins: A comprehensive survey of laminin–integrin interactions using recombinant α3β1, α6β1, α7β1 and α6β4 integrins

    Ryoko Nishiuchi;Junichi Takagi;Maria Hayashi;Hiroyuki Ido

  • Structure of integrin α5β1 in complex with fibronectin

    Junichi Takagi;Junichi Takagi;Konstantin Strokovich;Timothy A. Springer;Thomas Walz

  • Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation.

    Natalia Beglova;Stephen C. Blacklow;Junichi Takagi;Timothy A. Springer

  • Semaphorin 7A initiates T-cell-mediated inflammatory responses through α1β1 integrin

    Kazuhiro Suzuki;Tatsusada Okuno;Midori Yamamoto;R. Jeroen Pasterkamp

  • C-terminal Opening Mimics 'Inside-Out' Activation of Integrin alpha5beta1

    Junichi Takagi;Harold P. Erickson;Timothy A. Springer

  • Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair.

    Hyesung Jeon;Wuyi Meng;Junichi Takagi;Michael J. Eck

  • Reversibly locking a protein fold in an active conformation with a disulfide bond: Integrin αL I domains with high affinity and antagonist activity in vivo

    Motomu Shimaoka;Chafen Lu;Roger T. Palframan;Ulrich H. von Andrian

  • Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor

    Masamichi Nagae;Suyong Re;Emiko Mihara;Terukazu Nogi

  • Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

    Hiroshi Nishimasu;Shinichi Okudaira;Kotaro Hama;Emiko Mihara

  • The RGD motif in fibronectin is essential for development but dispensable for fibril assembly

    Seiichiro Takahashi;Michael Leiss;Markus Moser;Tomoo Ohashi

  • A Specific Interface between Integrin Transmembrane Helices and Affinity for Ligand

    Bing Hao Luo;Timothy A. Springer;Junichi Takagi

  • Locking in alternate conformations of the integrin αLβ2 I domain with disulfide bonds reveals functional relationships among integrin domains

    Chafen Lu;Motomu Shimaoka;Qun Zang;Junichi Takagi

  • Epitope Mapping of Antibodies to the C-Terminal Region of the Integrin β2 Subunit Reveals Regions that Become Exposed Upon Receptor Activation

    Chafen Lu;Mazen Ferzly;Junichi Takagi;Timothy A. Springer

  • Association of the Membrane Proximal Regions of the α and β Subunit Cytoplasmic Domains Constrains an Integrin in the Inactive State

    Chafen Lu;Junichi Takagi;Timothy A. Springer

Frequent Co-Authors

Timothy A. Springer
Timothy A. Springer Boston Children's Hospital
Yukinari Kato
Yukinari Kato Tohoku University
Yuji Inada
Yuji Inada Toin University of Yokohama
Motomu Shimaoka
Motomu Shimaoka Mie University
Kunio Matsumoto
Kunio Matsumoto Kanazawa University
Mika K. Kaneko
Mika K. Kaneko Tohoku University
Junken Aoki
Junken Aoki Tohoku University
Akira Kikuchi
Akira Kikuchi Osaka University
Osamu Nureki
Osamu Nureki University of Tokyo
Hiroaki Suga
Hiroaki Suga University of Tokyo

External Links

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Best Scientists Citing Junichi Takagi

Timothy A. Springer

Timothy A. Springer

Boston Children's Hospital

Publications: 123

Motomu Shimaoka

Motomu Shimaoka

Mie University

Publications: 61

Martin J. Humphries

Martin J. Humphries

University of Manchester

Publications: 49

Mika K. Kaneko

Mika K. Kaneko

Tohoku University

Publications: 40

Yukinari Kato

Yukinari Kato

Tohoku University

Publications: 40

Mark H. Ginsberg

Mark H. Ginsberg

University of California, San Diego

Publications: 39

Cheng Zhu

Cheng Zhu

Georgia Institute of Technology

Publications: 35

Horst Kessler

Horst Kessler

Technical University of Munich

Publications: 35

Yoshikazu Takada

Yoshikazu Takada

University of California, Davis

Publications: 34

Atsushi Kumanogoh

Atsushi Kumanogoh

Osaka University

Publications: 32

William F. DeGrado

William F. DeGrado

University of California, San Francisco

Publications: 30

Joel S. Bennett

Joel S. Bennett

University of Pennsylvania

Publications: 28

Junken Aoki

Junken Aoki

Tohoku University

Publications: 24

Christopher V. Carman

Christopher V. Carman

Harvard University

Publications: 22

Kiyotoshi Sekiguchi

Kiyotoshi Sekiguchi

Osaka University

Publications: 22

Edward F. Plow

Edward F. Plow

Cleveland Clinic Lerner College of Medicine

Publications: 22

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