What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Enzyme
His primary scientific interests are in Integrin, Lymphocyte function-associated antigen 1, Biophysics, Cell adhesion and Stereochemistry.
Motomu Shimaoka interconnects Ligand, Binding domain, Transmembrane domain, Intercellular Adhesion Molecule-1 and Conformational change in the investigation of issues within Integrin.
His biological study spans a wide range of topics, including Small interfering RNA, Molecular biology, RNA interference, Lymphocyte and Gene silencing.
His Biophysics study incorporates themes from Allosteric regulation and Small molecule.
His Cell adhesion research includes elements of Plasma protein binding, Signal transduction, G protein and Cell biology.
His Stereochemistry study typically links adjacent topics like Protein structure.
His most cited work include:
- Conformational Regulation of Integrin Structure and Function (462 citations)
- Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation (443 citations)
- Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. (437 citations)
What are the main themes of his work throughout his whole career to date?
Motomu Shimaoka focuses on Integrin, Cell biology, Cell adhesion, Immunology and Lymphocyte function-associated antigen 1.
The study incorporates disciplines such as Ligand, Biophysics, Stereochemistry, Cell adhesion molecule and Allosteric regulation in addition to Integrin.
Motomu Shimaoka has researched Stereochemistry in several fields, including Protein structure, Binding domain and Alpha.
His Cell biology research also works with subjects such as
- RNA interference which is related to area like Gene silencing, Small interfering RNA and Gene knockdown,
- Cell migration that intertwine with fields like Motility.
His Cell adhesion study combines topics in areas such as Intercellular Adhesion Molecule-1, In vitro and Molecular biology.
As a member of one scientific family, Motomu Shimaoka mostly works in the field of Lymphocyte function-associated antigen 1, focusing on Binding site and, on occasion, Isoflurane.
He most often published in these fields:
- Integrin (45.00%)
- Cell biology (35.56%)
- Cell adhesion (16.67%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (35.56%)
- Integrin (45.00%)
- Inflammation (14.44%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Integrin, Inflammation, Microvesicles and Cell adhesion.
His research in the fields of Homing, Crosstalk and Connexin overlaps with other disciplines such as Thrombomodulin.
His Integrin study improves the overall literature in Receptor.
His Inflammation research is multidisciplinary, relying on both Myokine, Immune system and Sepsis.
Motomu Shimaoka focuses mostly in the field of Microvesicles, narrowing it down to matters related to Endosome and, in some cases, Pannexin and Actin.
As part of one scientific family, Motomu Shimaoka deals mainly with the area of Cell adhesion, narrowing it down to issues related to the Extracellular matrix, and often Flow cytometry, Ligand and Cell membrane.
Between 2018 and 2021, his most popular works were:
- Connexins and Integrins in Exosomes. (27 citations)
- Exosomal regulation of lymphocyte homing to the gut (23 citations)
- Integrin and PD-1 Ligand Expression on Circulating Extracellular Vesicles in Systemic Inflammatory Response Syndrome and Sepsis. (17 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Enzyme
Motomu Shimaoka mainly investigates Cell biology, Integrin, Microvesicles, Inflammation and Sepsis.
His Cell biology research includes themes of Cancer cell, Cell morphology and Tube formation.
His research in Integrin intersects with topics in Renal function, Central nervous system, Transmembrane protein, Systemic inflammatory response syndrome and Cell adhesion.
His Microvesicles research focuses on subjects like Homing, which are linked to Chemokine, Cell adhesion molecule and Immune system.
His Inflammation research is multidisciplinary, incorporating elements of Extracellular, Serine, Peripheral blood mononuclear cell and Recombinant DNA.
The Sepsis study combines topics in areas such as Lung injury, Receptor expression and Type 2 immune response.
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