World's Best Scientists 2026 revealed!
Motomu Shimaoka

Motomu Shimaoka

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
11936
World Ranking
12037
National Ranking
823

Motomu Shimaoka publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Motomu Shimaoka sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 192 publications — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Motomu Shimaoka D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Motomu Shimaoka sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 60 D-Index — 41st percentile

41% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Motomu Shimaoka is affiliated with Mie University in Japan, focusing on biomedical research primarily within medicine and biochemistry, genetics, and molecular biology.

Their research spans several subfields including immunology, molecular biology, epidemiology, cancer research, and immunology and allergy. The main research topics cover cell adhesion molecules, extracellular vesicles in disease, sepsis diagnosis and treatment, microRNA in disease regulation, venous thromboembolism diagnosis and management, cancer-related molecular mechanisms, and intensive care unit cognitive disorders.

Motomu Shimaoka's recent published papers reveal active engagement in immunology, molecular cell biology, and infectious disease research. Selected recent publications include:

  • "Immune Deregulation in Sepsis and Septic Shock: Reversing Immune Paralysis by Targeting PD-1/PD-L1 Pathway" (2021, Frontiers in Immunology)
  • "Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin" (2020, Frontiers in Cell and Developmental Biology)
  • "The Spike Glycoprotein of SARS-CoV-2 Binds to β1 Integrins Expressed on the Surface of Lung Epithelial Cells" (2021, Viruses)
  • "Intestinal Epithelium-Derived Luminally Released Extracellular Vesicles in Sepsis Exhibit the Ability to Suppress TNF-α and IL-17A Expression in Mucosal Inflammation" (2020, International Journal of Molecular Sciences)
  • "Integrin Regulation in Immunological and Cancerous Cells and Exosomes" (2021, International Journal of Molecular Sciences)

Their frequent co-authors have included Eun Jeong Park, Eiji Kawamoto, Arong Gaowa, Katsuya Shiraki, and Hideto Shimpo, indicating ongoing collaborative work within these research areas.

Publication venues where Motomu Shimaoka has frequently contributed include the Journal of Clinical Medicine, International Journal of Molecular Sciences, Clinical and Applied Thrombosis/Hemostasis, Frontiers in Cell and Developmental Biology, and Experimental Cell Research.

Best Publications

  • Conformational Regulation of Integrin Structure and Function

    Motomu Shimaoka;Junichi Takagi;Timothy A Springer

  • Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation

    Motomu Shimaoka;Tsan Sam Xiao;Jin Huan Liu;Yuting Yang

  • Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target.

    Dan Peer;Eun Jeong Park;Yoshiyuki Morishita;Christopher V. Carman

  • Therapeutic antagonists and conformational regulation of integrin function

    Motomu Shimaoka;Timothy A. Springer

  • Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1

    Dan Peer;Pengcheng Zhu;Christopher V. Carman;Judy Lieberman

  • Activation of Leukocyte β2 Integrins by Conversion from Bent to Extended Conformations

    Noritaka Nishida;Can Xie;Motomu Shimaoka;Yifan Cheng

  • Reversibly locking a protein fold in an active conformation with a disulfide bond: Integrin αL I domains with high affinity and antagonist activity in vivo

    Motomu Shimaoka;Chafen Lu;Roger T. Palframan;Ulrich H. von Andrian

  • Identification of the target self-antigens in reperfusion injury

    Ming Zhang;Elisabeth M. Alicot;Isaac Chiu;Jinan Li

  • Ventilator-induced lung injury is associated with neutrophil infiltration, macrophage activation, and TGF-beta 1 mRNA upregulation in rat lungs.

    Hideaki Imanaka;Motomu Shimaoka;Nariaki Matsuura;Masaji Nishimura

  • Rolling Adhesion through an Extended Conformation of Integrin αLβ2 and Relation to α I and β I-like Domain Interaction

    Azucena Salas;Motomu Shimaoka;Avi N Kogan;Charlotte Harwood

  • RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice.

    Sang Soo Kim;Dan Peer;Dan Peer;Priti Kumar;Sandesh Subramanya

  • Locking in alternate conformations of the integrin αLβ2 I domain with disulfide bonds reveals functional relationships among integrin domains

    Chafen Lu;Motomu Shimaoka;Qun Zang;Junichi Takagi

  • Inflamed lymphatic endothelium suppresses dendritic cell maturation and function via Mac-1/ICAM-1-dependent mechanism.

    Simona Podgrabinska;Okebugwu Kamalu;Lloyd Mayer;Motomu Shimaoka

  • Computational design of an integrin I domain stabilized in the open high affinity conformation.

    Motomu Shimaoka;Julia M. Shifman;Hua Jing;Junichi Takagi

  • An isolated, surface-expressed I domain of the integrin αLβ2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond

    Chafen Lu;Motomu Shimaoka;Mazen Ferzly;Claus Oxvig

  • Set positive end-expiratory pressure during protective ventilation affects lung injury

    Muneyuki Takeuchi;Sven Goddon;Marisa Dolhnikoff;Motomu Shimaoka

  • Nonmuscle myosin heavy chain IIA mediates integrin LFA-1 de-adhesion during T lymphocyte migration

    Nicole A. Morin;Patrick W. Oakes;Young-Min Hyun;Dooyoung Lee

  • Importance of force linkage in mechanochemistry of adhesion receptors.

    Nathan S. Astrof;Azucena Salas;Motomu Shimaoka;JianFeng Chen

  • Requirement of α and β subunit transmembrane helix separation for integrin outside-in signaling

    Jieqing Zhu;Christopher V. Carman;Minsoo Kim;Motomu Shimaoka

  • Small Molecule Integrin Antagonists that Bind to the β2 Subunit I-like Domain and Activate Signals in One Direction and Block Them in the Other

    Motomu Shimaoka;Azucena Salas;Wei Yang;Gabriele Weitz-Schmidt

Frequent Co-Authors

Timothy A. Springer
Timothy A. Springer Boston Children's Hospital
Hiroshi Kiyono
Hiroshi Kiyono University of Tokyo
Christopher V. Carman
Christopher V. Carman Harvard University
Koji Suzuki
Koji Suzuki Suzuka University of Medical Science
Junichi Takagi
Junichi Takagi Osaka University
Jia-huai Wang
Jia-huai Wang Harvard University
Ulrich H. von Andrian
Ulrich H. von Andrian Harvard University
Takeshi Honda
Takeshi Honda Osaka University
Takashi Mashimo
Takashi Mashimo Osaka University
Tetsuya Iida
Tetsuya Iida Osaka University

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