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Biology and Biochemistry

D-Index
66
Citations
12255
World Ranking
8870
National Ranking
3944

Overview

Miriam C. Poirier is affiliated with the National Institutes of Health in the United States. Their research spans several areas within biochemistry, genetics, molecular biology, environmental science, and medicine, with a focus on molecular biology, toxicology, mutagenesis, pollution, genetics, and oncology.

The scientist's work covers a variety of topics, including:

  • Effects and risks of endocrine disrupting chemicals
  • Viral-associated cancers and disorders
  • Immune cell function and interaction
  • Lymphoma diagnosis and treatment
  • Toxic organic pollutants impact
  • Oil spill detection and mitigation
  • Microplastics and plastic pollution

Their recent publications reflect this breadth, with notable papers such as:

  • "Mechanisms of T cell evasion by Epstein-Barr virus and implications for tumor survival," 2023, published in Frontiers in Immunology
  • "Polycyclic Aromatic Hydrocarbon-DNA Adducts in Gulf of Mexico Sperm Whale Skin Biopsies Collected in 2012," 2021, published in Toxicological Sciences
  • "DNA damage in cetaceans: A mini review," 2021, published in Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  • "In-utero exposure to zidovudine-containing antiretroviral therapy and clonal hematopoiesis in HIV-exposed uninfected newborns," 2021, published in AIDS
  • "WR1065 conjugated to thiol-PEG polymers as novel anticancer prodrugs: broad spectrum efficacy, synergism, and drug resistance reversal," 2023, published in Frontiers in Oncology

Frequently published venues include:

  • Frontiers in Immunology
  • Toxicological Sciences
  • Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  • AIDS
  • Frontiers in Oncology

Collaborative efforts have involved several coauthors, notably:

  • John Pierce Wise
  • Dale M. Walker
  • Vernon E. Walker
  • Daniel Sausen
  • Laura Spiers

The scientist's research prominently addresses toxicological and environmental impacts on biological systems, alongside molecular mechanisms related to viral oncology and immune function. Their cross-disciplinary approach integrates environmental science themes such as pollution and oil spill detection with molecular biology and genetic toxicology, contributing to large-scale understanding of both environmental and health-related challenges.

Best Publications

  • Chemical-induced DNA damage and human cancer risk.

    Miriam C Poirier

  • Chemical carcinogenesis: from animal models to molecular models in one decade.

    Stuart H. Yuspa;Miriam C. Poirier

  • Transplacental Effects of 3′-Azido-2′,3′-Dideoxythymidine (AZT): Tumorigenicity in Mice and Genotoxicity in Mice and Monkeys

    Ofelia A. Olivero;Stuart H. Yuspa;Miriam C. Poirier;Lucy M. Anderson

  • Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy.

    Eddie Reed;Robert F. Ozols;Robert Tarone;Stuart H. Yuspa

  • Carcinogens and DNA damage.

    Jessica L. Barnes;Maria Zubair;Kaarthik John;Miriam C. Poirier

  • Carcinogen macromolecular adducts and their measurement

    Miriam C. Poirier;Regina M. Santella;Ainsley Weston

  • Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers.

    Miriam C Poirier;Rao L Divi;Lena Al-Harthi;Ofelia A Olivero

  • DNA adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for DNA adduct-based human cancer risk assessment

    Miriam C. Poirier;Frederick A. Beland

  • A pilot project in molecular cancer epidemiology: determination of benzo[a]pyrene — DNA adducts in animal and human tissues by immunoassays

    Frederica P. Perera;Miriam C. Poirier;Stuart H. Yuspa;Juichiro Nakayama

  • Quantitation of Benzo(a)pyrene-Deoxyguanosine Adducts by Radioimmunoassay

    M C Poirier;R Santella;I B Weinstein;D Grunberger

  • Quantitation of cis-diamminedichloroplatinum II (cisplatin)-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy.

    E. Reed;S. H. Yuspa;Leonard A Zwelling;R. F. Ozols

  • Methods of DNA adduct determination and their application to testing compounds for genotoxicity.

    D. H. Phillips;P. B. Farmer;F. A. Beland;R. G. Nath

  • DNA adducts, protein adducts, and sister chromatid exchange in cigarette smokers and nonsmokers.

    F P Perera;R M Santella;D Brenner;M C Poirier

  • Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs.

    Miriam C Poirier;Ofelia A Olivero;Dale M Walker;Vernon E Walker

  • Formation of polycyclic aromatic hydrocarbon-DNA adducts in peripheral white blood cells during consumption of charcoal-broiled beef

    N. Rothman;M.C. Poirier;M.E. Baser;J.A. Hansen

  • Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero.

    Ofelia A. Olivero;Gene M. Shearer;Claire A. Chougnet;Andrea A.S. Kovacs

  • Polycyclic aromatic hydrocarbon (PAH) exposure and DNA adduct semi-quantitation in archived human tissues.

    M Margaret Pratt;Kaarthik John;Allan B MacLean;Senait Afework

  • Interindividual differences in the concentration of 1-hydroxypyrene-glucuronide in urine and polycyclic aromatic hydrocarbon-DNA adducts in peripheral white blood cells after charbroiled beef consumption.

    D.H. Kang;N. Rothman;M.C. Poirier;A. Greenberg

  • Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3'-azido-3'-deoxythymidine.

    Mariana Gerschenson;Stephen W . Erhart;Catherine Y. Paik;Marisa C. St. Claire

  • Erratum: Chemical-induced DNA damage and human cancer risk

    Miriam C. Poirier

Frequent Co-Authors

Frederick A. Beland
Frederick A. Beland National Center for Toxicological Research
Stuart H. Yuspa
Stuart H. Yuspa National Institutes of Health
Eddie Reed
Eddie Reed National Institutes of Health
David H. Phillips
David H. Phillips King's College London
Kunio Nagashima
Kunio Nagashima National Institutes of Health
Regina M. Santella
Regina M. Santella Columbia University
Gene M. Shearer
Gene M. Shearer National Institutes of Health
Robert F. Ozols
Robert F. Ozols Fox Chase Cancer Center
Robert E. Tarone
Robert E. Tarone Vanderbilt University Medical Center
Frederica P. Perera
Frederica P. Perera Columbia University

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