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Biology and Biochemistry

D-Index
73
Citations
14635
World Ranking
6078
National Ranking
2858

Overview

Scott I. Simon is a researcher affiliated with the University of California, Davis in the United States, with a focus on multiple areas within medicine and biological sciences. Their work spans across disciplines such as Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology.

Their research concentrates on several subfields including Immunology, Molecular Biology, Immunology and Allergy, Physiology, and Genetics. Key topics explored in their publications involve Cell Adhesion Molecules Research, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Psoriasis: Treatment and Pathogenesis, Erythrocyte Function and Pathophysiology, Immune cells in cancer, Immune Response and Inflammation, and S100 Proteins and Annexins.

Recent papers authored or co-authored by Scott I. Simon include the following:

  • Host cells subdivide nutrient niches into discrete biogeographical microhabitats for gut microbes, 2022, Cell Host & Microbe
  • The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation, 2021, Cardiovascular Research
  • Evading the host response: Staphylococcus "hiding" in cortical bone canalicular system causes increased bacterial burden, 2020, Bone Research
  • Tensile force transmitted through LFA-1 bonds mechanoregulate neutrophil inflammatory response, 2020, Journal of Leukocyte Biology
  • Neutrophil Inflammatory Response Is Downregulated by Uptake of Superparamagnetic Iron Oxide Nanoparticle Therapeutics, 2020, Frontiers in Immunology

Scott I. Simon frequently publishes in venues including the Journal of Investigative Dermatology, Frontiers in Immunology, Cell Host & Microbe, Cardiovascular Research, and Bone Research.

Collaborations form a significant part of their research activities, with frequent co-authors being Vasilios A. Morikis, Anthony G. Passerini, Samuel Hwang, Gustavo Garcia, and Chongxiu Sun.

Best Publications

  • Relative Contribution of LFA-1 and Mac-1 to Neutrophil Adhesion and Migration

    Z.-M. Ding;J. E. Babensee;J. E. Babensee;S. I. Simon;Huifang Lu

  • Molecular mechanics and dynamics of leukocyte recruitment during inflammation.

    Scott I. Simon;Chad E. Green

  • L-selectin (CD62L) cross-linking signals neutrophil adhesive functions via the Mac-1 (CD11b/CD18) beta 2-integrin.

    S I Simon;A R Burns;A D Taylor;P K Gopalan

  • Neutrophil transendothelial migration is independent of tight junctions and occurs preferentially at tricellular corners.

    A R Burns;D C Walker;E S Brown;L T Thurmon

  • Dynamics of Neutrophil Infiltration during Cutaneous Wound Healing and Infection Using Fluorescence Imaging

    Min Ho Kim;Wei Liu;Dori L Borjesson;Fitz Roy E Curry

  • Ultrasound Radiation Force Enables Targeted Deposition of Model Drug Carriers loaded on Microbubbles

    Aaron F H Lum;Mark A Borden;Paul A Dayton;Dustin E Kruse

  • Neutrophil Tethering on E-Selectin Activates β2 Integrin Binding to ICAM-1 Through a Mitogen-Activated Protein Kinase Signal Transduction Pathway

    Scott I. Simon;Yu Hu;Dietmar Vestweber;C. Wayne Smith

  • Chemically distinct transition states govern rapid dissociation of single L-selectin bonds under force

    Evan Evans;Andrew Leung;Dan Hammer;Scott Simon

  • Functional Role of CD11c+ Monocytes in Atherogenesis Associated With Hypercholesterolemia

    Huaizhu Wu;R. Michael Gower;Hong Wang;Xiao Yuan Dai Perrard

  • Neutrophil-derived IL-1β Is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice

    John S. Cho;Yi Guo;Romela Irene Ramos;Frank Hebroni

  • GlyCAM-1, a physiologic ligand for L-selectin, activates beta 2 integrins on naive peripheral lymphocytes.

    Sam T. Hwang;Mark S. Singer;Patricia A. Giblin;Ted A. Yednock

  • A Mouse Model of Post-Arthroplasty Staphylococcus aureus Joint Infection to Evaluate In Vivo the Efficacy of Antimicrobial Implant Coatings

    Nicholas M. Bernthal;Alexandra I. Stavrakis;Fabrizio Billi;John S. Cho

  • Analysis of tight junctions during neutrophil transendothelial migration.

    A.R. Burns;R.A. Bowden;S.D. MacDonell;D.C. Walker

  • Venous Levels of Shear Support Neutrophil-Platelet Adhesion and Neutrophil Aggregation in Blood via P-Selectin and β2-Integrin

    K Konstantopoulos;S Neelamegham;S Neelamegham;A R Burns;E Hentzen

  • Neutrophil CD18-dependent arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow can be activated through L-selectin.

    P K Gopalan;C W Smith;H Lu;E L Berg

  • Mechanosensing at the Vascular Interface

    John M. Tarbell;Scott I. Simon;Fitz Roy E Curry

  • CD11c/CD18 Expression Is Upregulated on Blood Monocytes During Hypertriglyceridemia and Enhances Adhesion to Vascular Cell Adhesion Molecule-1

    R. Michael Gower;Huaizhu Wu;Huaizhu Wu;Greg A. Foster;Sridevi Devaraj

  • Enterococcus faecalis Bearing Aggregation Substance Is Resistant to Killing by Human Neutrophils despite Phagocytosis and Neutrophil Activation

    Robert M. Rakita;Robert M. Rakita;Natalie N. Vanek;Karen Jacques-Palaz;Mee Mee

  • L-selectin signaling of neutrophil adhesion and degranulation involves p38 mitogen-activated protein kinase.

    James E. Smolen;Thomas K. Petersen;Cody Koch;Stephen J. O'Keefe

  • Impaired integrin-dependent function in Wiskott-Aldrich syndrome protein-deficient murine and human neutrophils.

    Hong Zhang;Ulrich Y. Schaff;Chad E. Green;Hua Chen

Frequent Co-Authors

Lloyd S. Miller
Lloyd S. Miller Johns Hopkins University
Katherine W. Ferrara
Katherine W. Ferrara Stanford University
Paul A. Dayton
Paul A. Dayton University of North Carolina at Chapel Hill
Alan R. Burns
Alan R. Burns University of Houston
Christie M. Ballantyne
Christie M. Ballantyne Baylor College of Medicine
Leah Krubitzer
Leah Krubitzer University of California, Davis
Tingrui Pan
Tingrui Pan University of California, Davis
Donald E. Staunton
Donald E. Staunton CisThera (United States)
C. Wayne Smith
C. Wayne Smith Baylor College of Medicine
Gregg H. Recanzone
Gregg H. Recanzone University of California, Davis

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