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Biology and Biochemistry

D-Index
66
Citations
23836
World Ranking
8476
National Ranking
3812

Overview

Shile Huang is affiliated with Louisiana State University Health Sciences Center Shreveport in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these broad domains, Huang has contributed extensively to Molecular Biology, Immunology, Oncology, Epidemiology, and Infectious Diseases.

Their work covers several main topics, including:

  • Interferon and immune responses
  • Autophagy in disease and therapy
  • Rabies epidemiology and control
  • PI3K/AKT/mTOR signaling in cancer
  • Cytokine signaling pathways and interactions
  • Metabolism, diabetes, and cancer
  • Heavy metal exposure and toxicity

Huang has published numerous papers in various scientific venues. Frequent publication platforms include:

  • Cancer Research
  • Cells
  • Frontiers in Immunology
  • Cell Reports
  • Scientific Reports

Among recent notable publications are:

  • "The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds" (2023) in Cells
  • "mTOR Signaling in Metabolism and Cancer" (2020) in Cells
  • "Critical role of Syk-dependent STAT1 activation in innate antiviral immunity" (2021) in Cell Reports
  • "Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth" (2021) in Scientific Reports
  • "Cadmium induces mitochondrial ROS inactivation of XIAP pathway leading to apoptosis in neuronal cells" (2020) in The International Journal of Biochemistry & Cell Biology

Frequent coauthors collaborating with Huang include:

  • Long Chen
  • Jun Luo
  • Xiaofeng Guo
  • Ji-Long Chen
  • Xiaoqing Dong

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The targets of curcumin.

    Hongyu Zhou;Christopher S. Beevers;Shile Huang

  • Targeting mTOR signaling for cancer therapy.

    Shile Huang;Peter J Houghton

  • Host Immune Response to Influenza A Virus Infection.

    Xiaoyong Chen;Shasha Liu;Mohsan Ullah Goraya;Mohamed Maarouf

  • Rapamycins: mechanism of action and cellular resistance.

    Shile Huang;Mary Ann Bjornsti;Peter J. Houghton

  • Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells

    Christopher S. Beevers;Fengjun Li;Lei Liu;Shile Huang;Shile Huang

  • Role of mTOR signaling in tumor cell motility, invasion and metastasis.

    Hongyu Zhou;Shile Huang

  • Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

    Long Chen;Lei Liu;Shile Huang

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Sustained Activation of the JNK Cascade and Rapamycin-Induced Apoptosis Are Suppressed by p53/p21Cip1

    Shile Huang;Lili Shu;Michael B Dilling;John Easton

  • Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death.

    Long Chen;Baoshan Xu;Lei Liu;Yan Luo

  • Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells

    Long Chen;Baoshan Xu;Lei Liu;Yan Luo

  • Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

    Long Chen;Lei Liu;Jun Yin;Yan Luo

  • Updates of mTOR inhibitors

    Hongyu Zhou;Yan Luo;Shile Huang

  • Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.

    Shile Huang;Peter J Houghton

  • Curcumin disrupts the Mammalian target of rapamycin-raptor complex

    Christopher S. Beevers;Long Chen;Lei Liu;Yan Luo

  • Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways

    L Liu;F Li;J A Cardelli;K A Martin

  • Calcium Signaling Is Involved in Cadmium-Induced Neuronal Apoptosis via Induction of Reactive Oxygen Species and Activation of MAPK/mTOR Network

    Baoshan Xu;Sujuan Chen;Yan Luo;Zi Chen

  • The role of Cdc25A in the regulation of cell proliferation and apoptosis.

    Tao Shen;Shile Huang

Frequent Co-Authors

Peter J. Houghton
Peter J. Houghton The University of Texas Health Science Center at San Antonio
Evelina Gatti
Evelina Gatti Aix-Marseille University
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Sergio Lavandero
Sergio Lavandero University of Chile
Ian G. Mills
Ian G. Mills University of Oxford
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Yee-Joo Tan
Yee-Joo Tan National University of Singapore
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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