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Immunology
USA
2026

D-Index & Metrics

Immunology

D-Index
157
Citations
102974
World Ranking
93
National Ranking
60

Medicine

D-Index
159
Citations
104156
World Ranking
811
National Ranking
457

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Immunology in United States Leader Award

Overview

Klaus Ley is affiliated with Augusta University in the United States. Their research primarily spans immunology, molecular biology, and medicine, contributing extensively to the understanding of immune mechanisms in cardiovascular diseases.

The researcher has produced a significant body of work focusing on various topics, including:

  • Atherosclerosis and Cardiovascular Diseases
  • T-cell and B-cell Immunology
  • Single-cell and spatial transcriptomics
  • Cell Adhesion Molecules Research
  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Immune Response and Inflammation

Their recent publications demonstrate a concentration on immune cell behavior and vascular inflammation in atherosclerosis. Notable papers include:

  • "T cell subsets and functions in atherosclerosis," 2020, Nature Reviews Cardiology
  • "How the immune system shapes atherosclerosis: roles of innate and adaptive immunity," 2021, Nature Reviews Immunology
  • "Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas," 2020, Circulation Research
  • "Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production," 2022, Science
  • "Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis," 2022, Cardiovascular Research

Frequent co-authors collaborating with Klaus Ley include:

  • Marco Orecchioni
  • Payel Roy
  • Catherine C. Hedrick
  • Yanal Ghosheh
  • Sujit Silas Armstrong Suthahar

Their work is often published in venues such as:

  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Nature Cardiovascular Research
  • Circulation Research

Klaus Ley has contributed to book publications, including a title on atherosclerosis published by Springer Science+Business Media in 2022.

The scientist's extensive publications align with core fields of immunology and microbiology, biochemistry, genetics and molecular biology, and clinical medicine. They maintain a focus on both basic and translational aspects of immune cell function and cardiovascular health, supported by a research portfolio including detailed cellular and molecular studies within the immune system.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Getting to the site of inflammation: the leukocyte adhesion cascade updated

    Klaus Ley;Carlo Laudanna;Myron I. Cybulsky;Sussan Nourshargh

  • Development of Monocytes, Macrophages, and Dendritic Cells

    Frederic Geissmann;Markus G. Manz;Steffen Jung;Michael H. Sieweke

  • Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS-) vs. Alternatively Activated Macrophages.

    Marco Orecchioni;Yanal Ghosheh;Akula Bala Pramod;Klaus Ley;Klaus Ley

  • Immune and inflammatory mechanisms of atherosclerosis (

    Elena Galkina;Klaus Ley

  • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

    Tommaso Simoncini;Ali Hafezi-Moghadam;Derek P. Brazil;Klaus Ley

  • Anti-inflammatory Properties of Cytochrome P450 Epoxygenase-Derived Eicosanoids

    Koichi Node;Yuqing Huo;Xiulu Ruan;Baichun Yang

  • Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E

    Yuqing Huo;Andreas Schober;S. Bradley Forlow;David F. Smith

  • Phagocytosis of Apoptotic Neutrophils Regulates Granulopoiesis via IL-23 and IL-17

    Matthew A. Stark;Yuqing Huo;Tracy L. Burcin;Margaret A. Morris

  • Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice

    Maria L. Arbonés;David C. Ord;Klaus Ley;Howard Ratech

  • Vascular adhesion molecules in atherosclerosis

    Elena Galkina;Klaus Ley

  • The role of selectins in inflammation and disease

    Klaus Ley

  • Chemokines and chemokine receptors in leukocyte trafficking

    Timothy S. Olson;Klaus Ley

  • Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2

    William A. Kuziel;Sharon J. Morgan;Tracey C. Dawson;Stephanie Griffin

  • Immunity and Inflammation in Atherosclerosis.

    Dennis Wolf;Klaus Ley;Klaus Ley

  • Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis

    Clément Cochain;Ehsan Vafadarnejad;Panagiota Arampatzi;Jaroslav Pelisek

  • Platelet-neutrophil-interactions: linking hemostasis and inflammation.

    Alexander Zarbock;Alexander Zarbock;Renata K. Polanowska-Grabowska;Klaus Ley

  • Sequential contribution of L- and P-selectin to leukocyte rolling in vivo.

    K Ley;D C Bullard;M L Arbonés;R Bosse

  • Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice

    Fanli Meng;Kai Wang;Tomonori Aoyama;Sergei I. Grivennikov

  • RANTES Deposition by Platelets Triggers Monocyte Arrest on Inflamed and Atherosclerotic Endothelium

    Philipp von Hundelshausen;Philipp von Hundelshausen;Philipp von Hundelshausen;Kim S. C. Weber;Kim S. C. Weber;Kim S. C. Weber;Yuqing Huo;Yuqing Huo;Yuqing Huo;Amanda E. I. Proudfoot;Amanda E. I. Proudfoot;Amanda E. I. Proudfoot

  • Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation

    Alexander Zarbock;Kai Singbartl;Klaus Ley

Frequent Co-Authors

Alexander Zarbock
Alexander Zarbock University of Münster
Catherine C. Hedrick
Catherine C. Hedrick La Jolla Institute For Allergy & Immunology
Alexander L. Klibanov
Alexander L. Klibanov University of Virginia
Scott T. Acton
Scott T. Acton University of Virginia
Fabio Cominelli
Fabio Cominelli Case Western Reserve University
Markus Sperandio
Markus Sperandio Ludwig-Maximilians-Universität München
Yuqing Huo
Yuqing Huo Augusta University
Arthur L. Beaudet
Arthur L. Beaudet Baylor College of Medicine
Jonathan R. Lindner
Jonathan R. Lindner Oregon Health & Science University
Theresa T. Pizarro
Theresa T. Pizarro Case Western Reserve University

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