World's Best Scientists 2026 revealed!
Michel Desjardins

Michel Desjardins

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
13931
World Ranking
18217
National Ranking
638

Research.com Recognitions

  • 2010 - Fellow of the Royal Society of Canada Academy of Science

Overview

Michel Desjardins is affiliated with the University of Montreal in Canada and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research spans multiple subfields, including Molecular Biology, Neurology, Immunology, Sociology and Political Science, and Psychiatry and Mental Health.

The main topics addressed in their work include:

  • Inflammasome and immune disorders
  • Mitochondrial Function and Pathology
  • Parkinson's Disease Mechanisms and Treatments
  • Nuclear Receptors and Signaling
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Adolescent and Pediatric Healthcare

The scientist has published frequently in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the Canadian Association of Gastroenterology
  • The Journal of Immunology
  • Qualitative Health Research
  • Journal of Developmental and Physical Disabilities

Recent publications include:

  • "Understanding Gut Feelings: Transformations in Coping With Inflammatory Bowel Disease Among Young Adults" (2021), Qualitative Health Research
  • "Parkinson's genes orchestrate pyroptosis through selective trafficking of mtDNA to leaky lysosomes" (2023), bioRxiv (Cold Spring Harbor Laboratory)
  • "Mediating a Fragmented System: Partnership Experiences of Parents of Children with Neurodevelopmental and Neuromuscular Disabilities" (2020), Journal of Developmental and Physical Disabilities
  • "LRRK2 regulates the activation of the unfolded protein response and antigen presentation in macrophages during inflammation" (2023), bioRxiv (Cold Spring Harbor Laboratory)
  • "Modeling gene-environment interactions in Parkinson's Disease: Helicobacter pylori infection of Pink1−/− mice induces CD8 T cell-dependent motor and cognitive dysfunction" (2024), bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors in Michel Desjardins' research are:

  • Samantha Gruenheid
  • Sherilyn Junelle Recinto
  • Jo Anne Stratton
  • Heidi M. McBride
  • Alexandra Kazanova

In recognition of scientific contributions, Michel Desjardins was awarded the distinction of Fellow of the Royal Society of Canada in 2010, specifically in the Academy of Science category.

Best Publications

  • Phagosomes are competent organelles for antigen cross-presentation

    Mathieu Houde;Sylvie Bertholet;Etienne Gagnon;Sylvain Brunet

  • The Phagosome Proteome: Insight into Phagosome Functions

    Jérome Garin;Roberto Diez;Sylvie Kieffer;Jean-François Dermine

  • Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages.

    Etienne Gagnon;Sophie Duclos;Christiane Rondeau;Eric Chevet

  • Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

    M Desjardins;LA Huber;RG Parton;G Griffiths

  • Natural Resistance to Infection with Intracellular Pathogens: The Nramp1 Protein Is Recruited to the Membrane of the Phagosome

    Samantha Gruenheid;Elhanan Pinner;Michel Desjardins;Philippe Gros

  • Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection.

    Luc English;Magali Chemali;Johanne Duron;Christiane Rondeau

  • Parkinson’s Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation

    Diana Matheoud;Ayumu Sugiura;Angélique Bellemare-Pelletier;Annie Laplante

  • Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1 −/− mice

    Diana Matheoud;Tyler Cannon;Aurore Voisin;Anna-Maija Penttinen

  • Inhibition of Phagolysosomal Biogenesis by the Leishmania Lipophosphoglycan

    Michel Desjardins;Albert Descoteaux

  • Flotillin-1-enriched Lipid Raft Domains Accumulate on Maturing Phagosomes

    Jean-François Dermine;Sophie Duclos;Jérome Garin;François St-Louis

  • Biogenesis of phagolysosomes: the ‘kiss and run’ hypothesis

    Michel Desjardins

  • Molecular characterization of phagosomes.

    M Desjardins;J E Celis;G van Meer;H Dieplinger

  • ER-mediated phagocytosis: a new membrane for new functions.

    Michel Desjardins

  • Controlling the maturation of pathogen-containing vacuoles: a matter of life and death.

    Stéphane Méresse;Olivia Steele-Mortimer;Edgardo Moreno;Michel Desjardins

  • Phagocytosis: at the crossroads of innate and adaptive immunity.

    Isabelle Jutras;Michel Desjardins

  • The Phagosomal Proteome in Interferon-γ-Activated Macrophages

    Matthias Trost;Luc English;Sébastien Lemieux;Mathieu Courcelles

  • A systems biology analysis of the Drosophila phagosome

    L. M. Stuart;L. M. Stuart;J. Boulais;G. M. Charriere;E. J. Hennessy

  • Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages.

    S. Duclos;R. Diez;J. Garin;B. Papadopoulou

  • Organelle proteomics: looking at less to see more.

    Sylvain Brunet;Pierre Thibault;Etienne Gagnon;Paul Kearney

  • Phagocytosis: latex leads the way

    Michel Desjardins;Gareth Griffiths

Frequent Co-Authors

Pierre Thibault
Pierre Thibault University of Montreal
Albert Descoteaux
Albert Descoteaux Institut National de la Recherche Scientifique
Matthias Trost
Matthias Trost Newcastle University
Jean-Pierre Gorvel
Jean-Pierre Gorvel Aix-Marseille University
John J. M. Bergeron
John J. M. Bergeron McGill University
Gareth Griffiths
Gareth Griffiths University of Oslo
Lukas A. Huber
Lukas A. Huber Innsbruck Medical University
Robert G. Parton
Robert G. Parton University of Queensland
Philippe Pierre
Philippe Pierre Aix-Marseille University
Edgardo Moreno
Edgardo Moreno National University of Costa Rica

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