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Biology and Biochemistry

D-Index
76
Citations
20237
World Ranking
5058
National Ranking
39

Overview

Lukas A. Huber is affiliated with Innsbruck Medical University in Austria. Their research contributions span multiple disciplines within biochemistry, genetics, molecular biology, and medicine, focusing on various aspects of cellular and molecular processes.

Huber's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work further specializes in several subfields of study:

  • Molecular Biology
  • Cell Biology
  • Genetics
  • Immunology
  • Infectious Diseases

The primary research topics covered by Lukas A. Huber include:

  • Cellular transport and secretion
  • Pancreatic function and diabetes
  • SARS-CoV-2 and COVID-19 Research
  • Cancer Immunotherapy and Biomarkers
  • Autophagy in Disease and Therapy
  • Microtubule and mitosis dynamics
  • Celiac Disease Research and Management

Frequent publication venues for Huber's work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • eLife
  • Human Genetics
  • Nature

Some recent papers authored or co-authored include:

  • Natural products in drug discovery: advances and opportunities, 2021, Nature Reviews Drug Discovery
  • A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome, 2020, Nature
  • Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex, 2023, Nature
  • G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling, 2021, Cell
  • C5aR inhibition of nonimmune cells suppresses inflammation and maintains epithelial integrity in SARS-CoV-2-infected primary human airway epithelia, 2021, Journal of Allergy and Clinical Immunology

Huber collaborates frequently with a number of researchers. These frequent co-authors include:

  • Doris Wilflingseder
  • Michael W. Hess
  • Mariana E. G. de Araújo
  • Günther K. Bonn
  • Georg F. Vogel

Best Publications

  • Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

    M Desjardins;LA Huber;RG Parton;G Griffiths

  • SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

    Manuele Rebsamen;Lorena Pochini;Taras Stasyk;Mariana E. G. de Araújo

  • Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7

    Laura E. Via;Dusanka Deretic;Roseann J. Ulmer;Nina S. Hibler

  • Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane.

    Lukas A. Huber;Sanjay Pimplikar;Robert G. Parton;Hilkka Virta

  • Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth.

    Florian M. Corvinus;Carina Orth;Richard Moriggl;Svetlana A. Tsareva

  • Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton.

    Snezhana Oliferenko;Karin Paiha;Thomas Harder;Volker Gerke

  • Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction.

    David Teis;Winfried Wunderlich;Lukas A. Huber;Lukas A. Huber

  • Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins.

    Oliver Ullrich;Harald Stenmark;Kirill Alexandrov;Lukas A Huber

  • Comm Sorts Robo to Control Axon Guidance at the Drosophila Midline

    Krystyna Keleman;Srikanth Rajagopalan;Diana Cleppien;David Teis

  • Guidelines for the next 10 years of proteomics

    Marc R. Wilkins;Ron D. Appel;Jennifer E. Van Eyk;Maxey C.M. Chung

  • MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity

    Thomas Müller;Michael W Hess;Natalia Schiefermeier;Kristian Pfaller

  • Organelle proteomics: implications for subcellular fractionation in proteomics.

    Lukas A. Huber;Kristian Pfaller;Ilja Vietor

  • The Recycling Endosome of Madin-Darby Canine Kidney Cells Is a Mildly Acidic Compartment Rich in Raft Components

    Raluca Gagescu;Nicolas Demaurex;Robert G. Parton;Walter Hunziker

  • Molecular characterization of phagosomes.

    M Desjardins;J E Celis;G van Meer;H Dieplinger

  • Rab11, a small GTPase associated with both constitutive and regulated secretory pathways in PC12 cells.

    S. Urbé;L.A. Huber;M. Zerial;S.A. Tooze

  • Zooming in: fractionation strategies in proteomics.

    Taras Stasyk;Lukas A. Huber

  • Erythropoietin Contrastingly Affects Bacterial Infection and Experimental Colitis by Inhibiting Nuclear Factor-κB-Inducible Immune Pathways

    Manfred Nairz;Andrea Schroll;Alexander R Moschen;Thomas Sonnweber

  • p14–MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

    David Teis;Nicole Taub;Robert Kurzbauer;Diana Hilber

  • A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment.

    Winfried Wunderlich;Irene Fialka;David Teis;Arno Alpi

  • Identification of vaccine candidate antigens of Staphylococcus aureus by serological proteome analysis.

    Oresta Vytvytska;Eszter Nagy;Martin Blüggel;Helmut E. Meyer

Frequent Co-Authors

Michael W. Hess
Michael W. Hess Innsbruck Medical University
Georg Wick
Georg Wick Innsbruck Medical University
Andreas R. Janecke
Andreas R. Janecke Innsbruck Medical University
Robert G. Parton
Robert G. Parton University of Queensland
Kai Simons
Kai Simons Lipotype
Günther K. Bonn
Günther K. Bonn University of Innsbruck
Paul Dupree
Paul Dupree University of Cambridge
Marino Zerial
Marino Zerial Max Planck Society
Christian W. Huck
Christian W. Huck University of Innsbruck
Herbert Lindner
Herbert Lindner Innsbruck Medical University

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