World's Best Scientists 2026 revealed!
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Biology and Biochemistry
UK
2026

D-Index & Metrics

Neuroscience

D-Index
129
Citations
68236
World Ranking
287
National Ranking
38

Biology and Biochemistry

D-Index
129
Citations
68451
World Ranking
419
National Ranking
24

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2019 - Fellow of Pakistan Academy of Sciences
  • 1995 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology
  • 1995 - Sedgwick Memorial Medal, American Public Health Association

Overview

Khalid Iqbal is affiliated with the University of York in the United Kingdom and has a research focus that spans medicine and neuroscience. Their work primarily addresses key issues in physiology, neurology, cellular and molecular neuroscience, molecular biology, and psychiatry and mental health.

The main topics of their research include:

  • Alzheimer's disease research and treatments
  • Neuroscience and neuropharmacology research
  • Neuroinflammation and neurodegeneration mechanisms
  • Dementia and cognitive impairment research
  • Prion diseases and protein misfolding
  • Tryptophan and brain disorders
  • Neurogenesis and neuroplasticity mechanisms

Khalid Iqbal has published numerous papers, frequently contributing to the following venues:

  • Journal of Alzheimer's Disease
  • Alzheimer's & Dementia
  • Frontiers in Aging Neuroscience
  • Acta Neuropathologica Communications
  • Alzheimer's Research & Therapy

Recent publications include:

  • Does modulation of tau hyperphosphorylation represent a reasonable therapeutic strategy for Alzheimer's disease? From preclinical studies to the clinical trials, 2023, Molecular Psychiatry
  • Truncation of Tau selectively facilitates its pathological activities, 2020, Journal of Biological Chemistry
  • Multi-Targets: An Unconventional Drug Development Strategy for Alzheimer's Disease, 2022, Frontiers in Aging Neuroscience
  • Alzheimer's disease brain contains tau fractions with differential prion-like activities, 2021, Acta Neuropathologica Communications
  • Young blood plasma reduces Alzheimer's disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice, 2020, Alzheimer's Research & Therapy

The scientist frequently collaborates with several co-authors, among them:

  • Fei Liu
  • Cheng-Xin Gong
  • Chun-Ling Dai
  • Dandan Chu
  • Yunn Chyn Tung

Khalid Iqbal's research output shows interdisciplinary engagement spanning both clinical and molecular levels, reflecting a thorough exploration of neurodegenerative diseases and their underlying mechanisms.

Among the recognitions received are:

  • Fellow of Pakistan Academy of Sciences, 2019
  • Sedgwick Memorial Medal, American Public Health Association, 1995
  • Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology, 1995

Best Publications

  • Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

    Inge Grundke-Iqbal;Khalid Iqbal;Yunn-Chyn Tung;Maureen Quinlan

  • Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

    I Grundke-Iqbal;K Iqbal;M Quinlan;Y C Tung

  • Defeating Alzheimer's disease and other dementias: a priority for European science and society

    Bengt Winblad;Bengt Winblad;Philippe Amouyel;Sandrine Andrieu;Clive Ballard

  • Tau pathology in Alzheimer disease and other tauopathies

    Khalid Iqbal;Alejandra del C. Alonso;She Chen;M. Omar Chohan

  • Tau in Alzheimer disease and related tauopathies.

    Khalid Iqbal;Fei Liu;Cheng-Xin Gong;Inge Grundke-Iqbal

  • Hyperphosphorylation induces self-assembly of τ into tangles of paired helical filaments/straight filaments

    Alejandra del C. Alonso;Tanweer Zaidi;Michal Novak;Inge Grundke-Iqbal

  • Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules

    Alejandra del C. Alonso;Inge Grundke-Iqbal;Khalid Iqbal

  • Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease.

    E Köpke;Y.C. Tung;S Shaikh;A.C. Alonso

  • Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease

    C. Bancher;C. Brunner;H. Lassmann;H. Budka

  • Improved discrimination of AD patients using beta-amyloid((1-42)) and tau levels in CSF

    F Hulstaert;K Blennow;A Ivanoiu;HC Schoonderwaldt

  • Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation

    Fei Liu;Inge Grundke-Iqbal;Khalid Iqbal;Cheng-Xin Gong

  • Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease.

    Alejandra Del C. Alonso;Tanweer Zaidi;Inge Grundke-Iqbal;Khalid Iqbal

  • O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease

    Fei Liu;Khalid Iqbal;Inge Grundke-Iqbal;Gerald Warren Hart

  • Tau and neurodegenerative disease: the story so far

    Khalid Iqbal;Fei Liu;Cheng-Xin Gong

  • Mechanisms of tau-induced neurodegeneration

    Khalid Iqbal;Fei Liu;Cheng-Xin Gong;Alejandra del C. Alonso

  • The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives

    Lukas Wanka;Khalid Iqbal;Peter R. Schreiner

  • Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease.

    C.-X. Gong;K. Iqbal

  • Defective brain microtubule assembly in Alzheimer's disease.

    Khalid Iqbal;I. Grundke-Iqbal;T. Zaidi;P. A. Merz

  • Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration

    Jian-Zhi Wang;Inge Grundke-Iqbal;Khalid Iqbal

  • Distribution of Active Glycogen Synthase Kinase 3β (GSK-3β) in Brains Staged for Alzheimer Disease Neurofibrillary Changes

    Jin-Jing Pei;Eva Braak;Heiko Braak;Inge Grundke-Iqbal

  • Abnormal phosphorylation of the microtubule-associated protein? (tau) in Alzheimer cytoskeletal pathology

    I Grundke-Iqbal;K Iqbal;Y-C Tung;M Quinlan

Frequent Co-Authors

Inge Grundke-Iqbal
Inge Grundke-Iqbal University of York
Fei Liu
Fei Liu New York State Office for People With Developmental Disabilities
Cheng-Xin Gong
Cheng-Xin Gong City University of New York
Henryk M. Wisniewski
Henryk M. Wisniewski University of York
Bengt Winblad
Bengt Winblad Karolinska Institute
Kaj Blennow
Kaj Blennow University of Gothenburg
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Hans Lassmann
Hans Lassmann Medical University of Vienna
Yi Li
Yi Li University of Michigan–Ann Arbor
Kurt A. Jellinger
Kurt A. Jellinger Medical University of Vienna

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