Jian-Zhi Wang

Overview

Best Publications

• Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

  Tuo Qz;Tuo Qz;Tuo Qz;Lei P;Lei P;Jackman Ka;Li Xl

  716
  Citations

• Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration

  Jian-Zhi Wang;Inge Grundke-Iqbal;Khalid Iqbal

  685
  Citations

• Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration.

  Jian-Zhi Wang;Yi-Yuan Xia;Inge Grundke-Iqbal;Khalid Iqbal

  589
  Citations

• Phosphatase Activity Toward Abnormally Phosphorylated τ: Decrease in Alzheimer Disease Brain

  Cheng‐Xin Gong;Sadia Shaikh;Jian‐Zhi Wang;Tanweer Zaidi

  581
  Citations

• Microtubule-associated protein tau in development, degeneration and protection of neurons

  Jian-Zhi Wang;Fei Liu

  494
  Citations

• Glycosylation of microtubule-associated protein tau: an abnormal posttranslational modification in Alzheimer's disease.

  Jian-Zhi Wang;Inge Grundke-Iqbal;Khalid Iqbal

  452
  Citations

• Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer’s disease

  Zhentao Zhang;Mingke Song;Xia Liu;Seong Su Kang

  443
  Citations

• Dephosphorylation of Alzheimer Paired Helical Filaments by Protein Phosphatase-2A and −2B

  Jian-Zhi Wang;Cheng-Xin Gong;Tanweer Zaidi;Inge Grundke-Iqbal

  374
  Citations

• Current understanding of metal ions in the pathogenesis of Alzheimer’s disease

  Lu Wang;Ya-Ling Yin;Xin-Zi Liu;Peng Shen

  328
  Citations

• Activation of Glycogen Synthase Kinase-3 Inhibits Long-Term Potentiation with Synapse-Associated Impairments

  Ling-Qiang Zhu;Shao-Hui Wang;Dan Liu;Yang-Yang Yin

  302
  Citations

• Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory.

  Shi Jie Liu;Ai Hong Zhang;Hong Lian Li;Qun Wang

  285
  Citations

• Phosphorylation of tau antagonizes apoptosis by stabilizing beta-catenin, a mechanism involved in Alzheimer's neurodegeneration.

  Hong Lian Li;Hai Hong Wang;Shi Jie Liu;Yan Qiu Deng

  278
  Citations

• τ is phosphorylated by GSK‐3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A‐kinase

  Jian-zhi Wang;Qiongli Wu;Alan Smith;Inge Grundke-Iqbal

  272
  Citations

• The dual roles of cytokines in Alzheimer’s disease: update on interleukins, TNF-α, TGF-β and IFN-γ

  Cong Zheng;Xin-Wen Zhou;Jian-Zhi Wang

  269
  Citations

• Tau Becomes a More Favorable Substrate for GSK-3 When It Is Prephosphorylated by PKA in Rat Brain

  Shi Jie Liu;Jia Yu Zhang;Hong Lian Li;Zheng Yu Fang

  261
  Citations

• Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay.

  Yuan Yuan Hu;Shan Shu He;Xiaochuan Wang;Qiu Hong Duan

  255
  Citations

• Melatonin in Alzheimer’s Disease

  Li Lin;Qiong-Xia Huang;Shu-Sheng Yang;Jiang Chu

  250
  Citations

• Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila

  Danling Wang;Li Qian;Hui Xiong;Jiandong Liu

  247
  Citations

• SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination

  Hong-Bin Luo;Yi-Yuan Xia;Xi-Ji Shu;Zan-Chao Liu

  241
  Citations

• EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation

  Ying Yang;Xiaogang Shu;Xiaogang Shu;Dan Liu;You Shang;You Shang

  240
  Citations