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Kiyotoshi Sekiguchi

Kiyotoshi Sekiguchi

D-Index & Metrics

Biology and Biochemistry

D-Index
80
Citations
22932
World Ranking
4081
National Ranking
268

Overview

Kiyotoshi Sekiguchi is affiliated with Osaka University in Japan and specializes in research primarily within the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans multiple subfields including Molecular Biology, Immunology and Allergy, Cell Biology, and Cardiology and Cardiovascular Medicine.

The scientist's research topics cover a range of areas such as Cell Adhesion Molecules Research, Pluripotent Stem Cells Research, Tissue Engineering and Regenerative Medicine, 3D Printing in Biomedical Research, Cellular Mechanics and Interactions, RNA Interference and Gene Delivery, and Hair Growth and Disorders.

Frequently, they collaborate with coauthors including Yukimasa Taniguchi, Yamato Kikkawa, Motoyoshi Nomizu, Ritsuo Nishiuchi, and Binri Sasaki. Their publications have appeared in notable venues with the largest number of papers published in Glia, Scientific Reports, Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), and Matrix Biology Plus.

Notable recent papers authored or coauthored by Kiyotoshi Sekiguchi include:

  • Structural mechanism of laminin recognition by integrin (2021, Nature Communications)
  • Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions (2021, Nature Communications)
  • Pathogenic variants in THSD4, encoding the ADAMTS-like 6 protein, predispose to inherited thoracic aortic aneurysm (2020, Genetics in Medicine)
  • A Novel Fluorescent Reporter System Identifies Laminin-511/521 as Potent Regulators of Cardiomyocyte Maturation (2020, Scientific Reports)
  • Laminin is the ECM niche for trophoblast stem cells (2020, Life Science Alliance)

Best Publications

  • Self-organizing optic-cup morphogenesis in three-dimensional culture

    Mototsugu Eiraku;Nozomu Takata;Hiroki Ishibashi;Masako Kawada

  • Self-formation of optic cups and storable stratified neural retina from human ESCs.

    Tokushige Nakano;Satoshi Ando;Nozomu Takata;Masako Kawada

  • A simplified laminin nomenclature

    Monique Aumailley;Leena Bruckner-Tuderman;William G. Carter;Rainer Deutzmann

  • A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells

    Masato Nakagawa;Yukimasa Taniguchi;Sho Senda;Nanako Takizawa

  • Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells.

    Kotaro Sasaki;Shihori Yokobayashi;Tomonori Nakamura;Ikuhiro Okamoto

  • Ligand-binding specificities of laminin-binding integrins: A comprehensive survey of laminin–integrin interactions using recombinant α3β1, α6β1, α7β1 and α6β4 integrins

    Ryoko Nishiuchi;Junichi Takagi;Maria Hayashi;Hiroyuki Ido

  • Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation

    Daisuke Doi;Bumpei Samata;Mitsuko Katsukawa;Tetsuhiro Kikuchi

  • Laminin E8 fragments support efficient adhesion and expansion of dissociated human pluripotent stem cells

    Takamichi Miyazaki;Sugiko Futaki;Hirofumi Suemori;Yukimasa Taniguchi

  • The basement membrane of hair follicle stem cells is a muscle cell niche

    Hironobu Fujiwara;Manuela Ferreira;Giacomo Donati;Denise K. Marciano

  • Recombinant human laminin isoforms can support the undifferentiated growth of human embryonic stem cells.

    Takamichi Miyazaki;Sugiko Futaki;Kouichi Hasegawa;Miwa Kawasaki

  • Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins.

    Y. Kikkawa;N. Sanzen;H. Fujiwara;A. Sonnenberg

  • Modulation of Cell-adhesive Activity of Fibronectin by the Alternatively Spliced EDA Segment

    Ri-ichiroh Manabe;Naoko Oh-e;Toshinaga Maeda;Tomohiko Fukuda

  • Laminin-10/11 and Fibronectin Differentially Regulate Integrin- dependent Rho and Rac Activation via p130Cas-CrkII-DOCK180 Pathway

    Jianguo Gu;Yasuhiro Sumida;Noriko Sanzen;Kiyotoshi Sekiguchi

  • Co-ordinated ocular development from human iPS cells and recovery of corneal function

    Ryuhei Hayashi;Yuki Ishikawa;Yuzuru Sasamoto;Ryosuke Katori

  • Introduction of Bisecting GlcNAc into Integrin α5β1 Reduces Ligand Binding and Down-regulates Cell Adhesion and Cell Migration

    Tomoya Isaji;Jianguo Gu;Ryoko Nishiuchi;Yanyang Zhao

  • Isolation and Characterization of Laminin-10/11 Secreted by Human Lung Carcinoma Cells : LAMININ-10/11 MEDIATES CELL ADHESION THROUGH INTEGRIN α3β1

    Yamato Kikkawa;Noriko Sanzen;Kiyotoshi Sekiguchi

  • Integrin α3β1-mediated interaction with laminin-5 stimulates adhesion, migration and invasion of malignant glioma cells

    Yuji Fukushima;Takanori Ohnishi;Norio Arita;Toru Hayakawa

  • Potentiation of the ligand-binding activity of integrin α3β1 via association with tetraspanin CD151

    Ryoko Nishiuchi;Noriko Sanzen;Shigeyuki Nada;Yasuhiro Sumida

  • Anti-laminin gamma-1 pemphigoid

    Teruki Dainichi;Sadamu Kurono;Bungo Ohyama;Norito Ishii

  • Purification and Characterization of Human Laminin-8 LAMININ-8 STIMULATES CELL ADHESION AND MIGRATION THROUGH α3β1 AND α6β1INTEGRINS

    Hironobu Fujiwara;Yamato Kikkawa;Noriko Sanzen;Kiyotoshi Sekiguchi

Frequent Co-Authors

Koiti Titani
Koiti Titani Fujita Health University
Sen-itiroh Hakomori
Sen-itiroh Hakomori Pacific Northwest Diabetes Research Institute
Jianguo Gu
Jianguo Gu Tohoku Medical and Pharmaceutical University
Yoshiki Sawa
Yoshiki Sawa Osaka University
Ikunoshin Kato
Ikunoshin Kato Fujita Health University
Ismo Virtanen
Ismo Virtanen University of Helsinki
Koji Eto
Koji Eto Kyoto University
Takako Sasaki
Takako Sasaki Oita University
Lydia Sorokin
Lydia Sorokin University of Münster
Masato Nakagawa
Masato Nakagawa Kyoto University

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