D-Index & Metrics Best Publications
Kiyotoshi Sekiguchi

Kiyotoshi Sekiguchi

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 8,585 135 World Ranking 6706 National Ranking 468

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Cancer

His main research concerns Fibronectin, Cell biology, Integrin, Molecular biology and Laminin. The study incorporates disciplines such as Alternative splicing, Binding site and Precursor mRNA in addition to Fibronectin. Kiyotoshi Sekiguchi interconnects Receptor, Angiogenesis and Induced pluripotent stem cell in the investigation of issues within Cell biology.

His study looks at the relationship between Integrin and fields such as Cell migration, as well as how they intersect with chemical problems. His studies deal with areas such as Immunohistochemistry, Cell adhesion and Focal adhesion as well as Molecular biology. Kiyotoshi Sekiguchi combines subjects such as Internal medicine, Endocrinology and Basement membrane with his study of Laminin.

His most cited work include:

  • Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. (226 citations)
  • Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins. (200 citations)
  • Isolation and Characterization of Laminin-10/11 Secreted by Human Lung Carcinoma Cells : LAMININ-10/11 MEDIATES CELL ADHESION THROUGH INTEGRIN α3β1 (193 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Laminin, Molecular biology, Integrin and Fibronectin. His Cell biology research integrates issues from Cell and Induced pluripotent stem cell. His work is dedicated to discovering how Laminin, Pathology are connected with Adenocarcinoma and Cancer research and other disciplines.

His work investigates the relationship between Molecular biology and topics such as Transcription factor that intersect with problems in Endoderm. His biological study spans a wide range of topics, including Integrin alpha M, Cell migration and Cell adhesion. His studies in Fibronectin integrate themes in fields like Binding site and Alternative splicing.

He most often published in these fields:

  • Cell biology (45.16%)
  • Laminin (41.40%)
  • Molecular biology (32.80%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (45.16%)
  • Laminin (41.40%)
  • Integrin (27.42%)

In recent papers he was focusing on the following fields of study:

Kiyotoshi Sekiguchi spends much of his time researching Cell biology, Laminin, Integrin, Induced pluripotent stem cell and Pathology. His Cell biology research is multidisciplinary, incorporating elements of Cell and Cellular differentiation. Laminin is a subfield of Extracellular matrix that he tackles.

His research integrates issues of Type IV collagen, In vitro, Endoderm and In vivo in his study of Integrin. His study in Pathology is interdisciplinary in nature, drawing from both Muscular dystrophy and Dermal papillae. His A protein research is multidisciplinary, incorporating perspectives in Molecular biology and Cell culture.

Between 2016 and 2021, his most popular works were:

  • Laminin 511 is a target antigen in autoimmune pancreatitis (66 citations)
  • Generation of safe and therapeutically effective human induced pluripotent stem cell-derived hepatocyte-like cells for regenerative medicine (35 citations)
  • Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells. (35 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

His scientific interests lie mostly in Laminin, Cell biology, Stem cell, Induced pluripotent stem cell and Extracellular matrix. His Laminin study integrates concerns from other disciplines, such as Cell culture, Integrin, Integrin binding, Biophysics and Transplantation. His research investigates the connection between Cell culture and topics such as A protein that intersect with issues in Molecular biology.

His Integrin research is multidisciplinary, relying on both In vitro and In vivo. His study of Function is a part of Cell biology. In his study, Angiogenesis and Autoantibody is inextricably linked to Pathology, which falls within the broad field of Extracellular matrix.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins.

Y. Kikkawa;N. Sanzen;H. Fujiwara;A. Sonnenberg.
Journal of Cell Science (2000)

273 Citations

Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells.

Kotaro Sasaki;Shihori Yokobayashi;Tomonori Nakamura;Ikuhiro Okamoto.
Cell Stem Cell (2015)

269 Citations

Modulation of Cell-adhesive Activity of Fibronectin by the Alternatively Spliced EDA Segment

Ri-ichiroh Manabe;Naoko Oh-e;Toshinaga Maeda;Tomohiko Fukuda.
Journal of Cell Biology (1997)

264 Citations

Laminin-10/11 and Fibronectin Differentially Regulate Integrin- dependent Rho and Rac Activation via p130Cas-CrkII-DOCK180 Pathway

Jianguo Gu;Yasuhiro Sumida;Noriko Sanzen;Kiyotoshi Sekiguchi.
Journal of Biological Chemistry (2001)

236 Citations

Isolation and Characterization of Laminin-10/11 Secreted by Human Lung Carcinoma Cells : LAMININ-10/11 MEDIATES CELL ADHESION THROUGH INTEGRIN α3β1

Yamato Kikkawa;Noriko Sanzen;Kiyotoshi Sekiguchi.
Journal of Biological Chemistry (1998)

226 Citations

Integrin α3β1‐mediated interaction with laminin‐5 stimulates adhesion, migration and invasion of malignant glioma cells

Yuji Fukushima;Takanori Ohnishi;Norio Arita;Toru Hayakawa.
International Journal of Cancer (1998)

214 Citations

Introduction of Bisecting GlcNAc into Integrin α5β1 Reduces Ligand Binding and Down-regulates Cell Adhesion and Cell Migration

Tomoya Isaji;Jianguo Gu;Ryoko Nishiuchi;Yanyang Zhao.
Journal of Biological Chemistry (2004)

213 Citations

Peptide ligands for integrin alpha v beta 3 selected from random phage display libraries.

Judith M. Healy;Ohoshi Murayama;Toshinaga Maeda;Kazuhiro Yoshino.
Biochemistry (1995)

194 Citations

Purification and Characterization of Human Laminin-8 LAMININ-8 STIMULATES CELL ADHESION AND MIGRATION THROUGH α3β1 AND α6β1INTEGRINS

Hironobu Fujiwara;Yamato Kikkawa;Noriko Sanzen;Kiyotoshi Sekiguchi.
Journal of Biological Chemistry (2001)

189 Citations

Domain structure of human plasma fibronectin. Differences and similarities between human and hamster fibronectins.

Kiyotoshi Sekiguchi;Sen-itiroh Hakomori.
Journal of Biological Chemistry (1983)

174 Citations

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