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Karl Tryggvason

Karl Tryggvason

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Molecular Biology
Sweden
2026

D-Index & Metrics

Molecular Biology

D-Index
128
Citations
44273
World Ranking
198
National Ranking
5

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in Sweden Leader Award
  • 2025 - Research.com Molecular Biology in Sweden Leader Award
  • 2023 - Research.com Molecular Biology in Sweden Leader Award

Overview

Karl Tryggvason is affiliated with the Karolinska Institute in Sweden and has produced a significant body of research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans various subfields including Molecular Biology, Nephrology, Surgery, Hematology, and Genetics.

The scientist's research covers a range of important topics such as Renal Diseases and Glomerulopathies, Chronic Kidney Disease and Diabetes, Congenital Heart Defects Research, Tissue Engineering and Regenerative Medicine, Cell Adhesion Molecules Research, Acute Myeloid Leukemia Research, and Genetic and Kidney Cyst Diseases.

Frequent publication venues for their work include:

  • The Journal of Experimental Medicine
  • Molecular Cell
  • Nature
  • Blood
  • Scientific Reports

Significant recent papers authored or co-authored by Karl Tryggvason are:

  • "A high-resolution map of human RNA translation", 2022, Molecular Cell
  • "Periportal macrophages protect against commensal-driven liver inflammation", 2024, Nature
  • "Viral proteases activate the CARD8 inflammasome in the human cardiovascular system", 2022, The Journal of Experimental Medicine
  • "Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression", 2021, Blood
  • "Podocyte-specific Crb2 knockout mice develop focal segmental glomerulosclerosis", 2021, Scientific Reports

The scientist frequently collaborates with several co-authors, among whom Lynn Yap, Enrico Petretto, and Li Yen Chong appear most often. Other notable frequent collaborators include Swarnaseetha Adusumalli and Clarissa Tan.

Best Publications

  • Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome

    Marjo Kestilä;Ulla Lenkkeri;Minna Männikkö;Jane Lamerdin

  • A simplified laminin nomenclature

    Monique Aumailley;Leena Bruckner-Tuderman;William G. Carter;Rainer Deutzmann

  • Identification of mutations in the COL4A5 collagen gene in Alport syndrome.

    David F. Barker;Sirkka Liisa Hostikka;Jing Zhou;Louise T. Chow

  • A new nomenclature for the laminins.

    Robert E. Burgeson;Matthias Chiquet;Rainer Deutzmann;Peter Ekblom

  • Genomic instability in laminopathy-based premature aging

    Baohua Liu;Jianming Wang;Kui Ming Chan;Wai Mui Tjia

  • Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy.

    A Helbling-Leclerc;X Zhang;H Topaloglu;C Cruaud

  • Type IV collagen: structure, gene organization, and role in human diseases. Molecular basis of Goodpasture and Alport syndromes and diffuse leiomyomatosis.

    B G Hudson;S T Reeders;K Tryggvason

  • X-linked Alport Syndrome Natural History in 195 Families and Genotype- Phenotype Correlations in Males

    Jean Philippe Jais;Bertrand Knebelmann;Iannis Giatras;Mario De Marchi

  • The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation.

    Ganka Nikolova;Normund Jabs;Irena Konstantinova;Anna Domogatskaya

  • Defective Prelamin A Processing and Muscular and Adipocyte Alterations in Zmpste24 Metalloproteinase-Deficient Mice

    Alberto M. Pendás;Zhongjun Zhou;Juan Cadiñanos;José M.P. Freije

  • Laminin-5 Is a Marker of Invading Cancer Cells in Some Human Carcinomas and Is Coexpressed with the Receptor for Urokinase Plasminogen Activator in Budding Cancer Cells in Colon Adenocarcinomas

    Charles Pyke;Sirpa Salo;Elisabeth Ralfkiær;John Rømer

  • Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation

    Ignacio Varela;Juan Cadiñanos;Alberto M. Pendás;Ana Gutiérrez-Fernández

  • Structure of the Gene for Congenital Nephrotic Syndrome of the Finnish Type (NPHS1) and Characterization of Mutations

    Ulla Lenkkeri;Minna Männikkö;Paula McCready;Jane Lamerdin

  • Laminin isoforms in tumor invasion, angiogenesis and metastasis.

    Manuel Patarroyo;Karl Tryggvason;Ismo Virtanen

  • Localization of Messenger RNA for Mr 72,000 and 92,000 Type IV Collagenases in Human Skin Cancers by in Situ Hybridization

    Charles Pyke;Elisabeth Ralfkiær;Piricko Huhtala;Tina Hurskainen

  • Deletion of the Laminin α4 Chain Leads to Impaired Microvessel Maturation

    Jill Thyboll;Jarkko Kortesmaa;Renhai Cao;Raija Soininen

  • Functional Diversity of Laminins

    Anna Domogatskaya;Sergey Rodin;Karl Tryggvason

  • Structure of the human type IV collagenase gene.

    P Huhtala;L T Chow;K Tryggvason

  • Mutations in the gamma 2 chain gene (LAMC2) of kalinin/laminin 5 in the junctional forms of epidermolysis bullosa.

    Leena Pulkkinen;Angela M. Christiano;Tomi Airenne;Heli Haakana

  • X-Linked Alport Syndrome: Natural History and Genotype-Phenotype Correlations in Girls and Women Belonging to 195 Families: A "European Community Alport Syndrome Concerted Action" study

    Jean Philippe Jais;Bertrand Knebelmann;Iannis Giatras;Mario De Marchi

Frequent Co-Authors

Christer Betsholtz
Christer Betsholtz Uppsala University
Manuel E. Patarroyo
Manuel E. Patarroyo National University of Colombia
Jing Zhou
Jing Zhou Harvard University
Kjell Hultenby
Kjell Hultenby Karolinska Institute
Per-Henrik Groop
Per-Henrik Groop University of Helsinki
Ismo Virtanen
Ismo Virtanen University of Helsinki
Corinne Antignac
Corinne Antignac Institut Imagine
Jean-Michel Foidart
Jean-Michel Foidart University of Liège
Stephen T. Reeders
Stephen T. Reeders Brigham and Women's Hospital
Enrico Petretto
Enrico Petretto Duke NUS Graduate Medical School

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