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Yoshifumi Ninomiya

Yoshifumi Ninomiya

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
16916
World Ranking
4648
National Ranking
307

Overview

Yoshifumi Ninomiya was a researcher affiliated with Okayama University in Japan. Their academic work spanned various fields primarily within biochemistry, genetics, molecular biology, and medicine. Over the course of their career, they contributed to multiple subfields including genetics, molecular biology, oncology, artificial intelligence, and dermatology.

Their research often intersected with several main topics such as AI in cancer detection, cleft lip and palate research, dental development and anomalies, cutaneous melanoma detection and management, skin protection and aging, craniofacial disorders and treatments, and radiomics and machine learning in medical imaging.

Among the recent publications authored or co-authored by Ninomiya were:

  • Classification of large-scale image database of various skin diseases using deep learning, 2021, International Journal of Computer Assisted Radiology and Surgery
  • Synchondrosis fusion contributes to the progression of postnatal craniofacial dysmorphology in syndromic craniosynostosis, 2022, Journal of Anatomy
  • Development and multi-institutional validation of an artificial intelligence-based diagnostic system for gastric biopsy, 2022, Cancer Science
  • The role of sonic hedgehog signaling in the oropharyngeal epithelium during jaw development, 2024, Congenital Anomalies

Throughout their career, Ninomiya collaborated frequently with several co-authors including Masaki Takechi, Daisuke Koyabu, Toshiko Furutera, Sachiko Iseki, and Masaya Tanaka.

Their contributions were regularly published in specialized journals such as:

  • International Journal of Computer Assisted Radiology and Surgery
  • Journal of Anatomy
  • Cancer Science
  • Congenital Anomalies

Ninomiya's work notably involved the application of artificial intelligence techniques to medical fields, particularly the use of deep learning in disease classification and diagnosis. This included advances in cancer detection and analysis, with a focus on integrating AI systems into pathological and radiological workflows.

Within craniofacial and dental research, their publications explored developmental biology mechanisms, such as signaling pathways involved in oropharyngeal epithelium and the morphological progression of craniofacial abnormalities. Their studies contributed to the understanding of congenital anomalies and potential diagnostic approaches.

The research interest in dermatology encompassed large-scale image databases for skin conditions, which aligned with work on melanoma detection and skin protection strategies.

Best Publications

  • Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development

    Ernst Pöschl;Ursula Schlötzer-Schrehardt;Bent Brachvogel;Kenji Saito

  • A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis

    Y Li;D.A Lacerda;M.L Warman;D.R Beier

  • Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies.

    Yoshifumi Ninomiya;Megumi Kagawa;Ken Ichi Iyama;Ichiro Naito

  • New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo.

    Eric Petitclerc;Ariel Boutaud;Archie Prestayko;Jingsong Xu

  • Glomerular basement membrane. Identification of a novel disulfide-cross-linked network of alpha3, alpha4, and alpha5 chains of type IV collagen and its implications for the pathogenesis of Alport syndrome.

    Sripad Gunwar;Fernando Ballester;Milton E. Noelken;Yoshikazu Sado

  • Establishment by the rat lymph node method of epitope-defined monoclonal antibodies recognizing the six different α chains of human type IV collagen

    Yoshikazu Sado;Megumi Kagawa;Yumiko Kishiro;Katsuyuki Sugihara

  • Distinct Target-Derived Signals Organize Formation, Maturation, and Maintenance of Motor Nerve Terminals

    Michael A. Fox;Joshua R. Sanes;Dorin Bogdan Borza;Veraragavan P. Eswarakumar

  • Type IV Collagen of the Glomerular Basement Membrane EVIDENCE THAT THE CHAIN SPECIFICITY OF NETWORK ASSEMBLY IS ENCODED BY THE NONCOLLAGENOUS NC1 DOMAINS

    Ariel Boutaud;Dorin-Bogdan Borza;Olga Bondar;Sripad Gunwar

  • Compositional differences between infant and adult human corneal basement membranes.

    Andrea Kabosova;Dimitri T. Azar;Gregory A. Bannikov;Kevin P. Campbell

  • Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome

    Roy Morello;Guang Zhou;Sandra D. Dreyer;Sandra D. Dreyer;Scott J. Harvey

  • High Affinity Binding of Latent Matrix Metalloproteinase-9 to the α2(IV) Chain of Collagen IV

    Matthew W. Olson;Marta Toth;David C. Gervasi;Yoshikazu Sado

  • Basement membrane abnormalities in human eyes with diabetic retinopathy.

    A V Ljubimov;R E Burgeson;R J Butkowski;J R Couchman

  • The NC1 domain of collagen IV encodes a novel network composed of the alpha 1, alpha 2, alpha 5, and alpha 6 chains in smooth muscle basement membranes.

    Dorin-Bogdan Borza;Olga Bondar;Yoshifumi Ninomiya;Yoshikazu Sado

  • Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas.

    Mehmet Gunduz;Hitoshi Nagatsuka;Kadir Demircan;Esra Gunduz

  • Increased Expression of Connective Tissue Growth Factor in the Infarct Zone of Experimentally Induced Myocardial Infarction in Rats

    Hiromichi Ohnishi;Takefumi Oka;Shozo Kusachi;Tohru Nakanishi

  • Organization and expression of basement membrane collagen IV genes and their roles in human disorders.

    Yoshikazu Sado;Megumi Kagawa;Ichiro Naito;Yasuyoshi Ueki

  • Synthesis and characterization of cDNA encoding a cartilage-specific short collagen

    Yoshifumi Ninomiya;Bjorn Reino Olsen

  • Differential localization of mRNAs of collagen types I and II in chick fibroblasts, chondrocytes, and corneal cells by in situ hybridization using cDNA probes.

    Masando Hayashi;Yoshifumi Ninomiya;Janey Parsons;Kimiko Hayashi

  • Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis

    Tomoko Kawabata;Keiichiro Nishida;Koji Takasugi;Hiroko Ogawa

  • Role of distinct type IV collagen networks in glomerular development and function

    Scott J. Harvey;Keqin Zheng;Yoshikazu Sado;Ichiro Naito

Frequent Co-Authors

Yoshikazu Sado
Yoshikazu Sado Okayama University
Billy G. Hudson
Billy G. Hudson Vanderbilt University Medical Center
Yasushi Shiratori
Yasushi Shiratori Okayama University
Björn Olsen
Björn Olsen Harvard University
Alexander V. Ljubimov
Alexander V. Ljubimov Cedars-Sinai Medical Center
Raymond J. Rodgers
Raymond J. Rodgers University of Adelaide
Francesco Ramirez
Francesco Ramirez Icahn School of Medicine at Mount Sinai
Hideo Baba
Hideo Baba Kumamoto University
Reinhard Fässler
Reinhard Fässler Max Planck Society
Robert E. Burgeson
Robert E. Burgeson Harvard University

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