His primary areas of study are Molecular biology, Extracellular matrix, Type IV collagen, Basement membrane and Immunology. The Molecular biology study combines topics in areas such as Messenger RNA, In situ hybridization, Transmembrane protein, Blot and Monoclonal antibody. His Extracellular matrix research includes themes of Cornea and Cartilage.
His Type IV collagen research is multidisciplinary, relying on both Alport syndrome, Glomerular basement membrane and Collagen receptor. In his study, Laminin is strongly linked to Perlecan, which falls under the umbrella field of Basement membrane. His Immunology study integrates concerns from other disciplines, such as Parenchyma, Pathology, Integrin, Albumin and Clone.
Yoshifumi Ninomiya spends much of his time researching Molecular biology, Basement membrane, Type IV collagen, Pathology and Extracellular matrix. His work carried out in the field of Molecular biology brings together such families of science as Gene expression, In situ hybridization, Complementary DNA, Messenger RNA and Gene. The concepts of his Basement membrane study are interwoven with issues in Epithelium, Membrane, Biochemistry, Immunostaining and Monoclonal antibody.
His Type IV collagen research integrates issues from Alport syndrome, Endocrinology, Glomerular basement membrane, Anatomy and Internal medicine. His studies in Pathology integrate themes in fields like Cancer cell, Metastasis and Immunology. His Extracellular matrix research is classified as research in Cell biology.
His scientific interests lie mostly in Internal medicine, Molecular biology, Basement membrane, Pathology and Extracellular matrix. In his study, which falls under the umbrella issue of Internal medicine, Basal lamina is strongly linked to Endocrinology. His Molecular biology study combines topics in areas such as Regulation of gene expression, Reporter gene, Gene expression, Gene and Thrombospondin.
He regularly ties together related areas like Type IV collagen in his Basement membrane studies. His Type IV collagen research includes elements of Immunohistochemistry and Epithelium. In his research on the topic of Extracellular matrix, Membrane is strongly related with Anatomy.
The scientist’s investigation covers issues in Molecular biology, Internal medicine, Extracellular matrix, Endocrinology and Laminin. The various areas that Yoshifumi Ninomiya examines in his Molecular biology study include Gene expression, Arthritis, Thrombospondin, Chromatin immunoprecipitation and Rheumatoid arthritis. His study in Extracellular matrix is interdisciplinary in nature, drawing from both Nod, Neuroscience and Basement membrane.
His Basement membrane research incorporates elements of Type IV collagen, Podocyte, Triple staining and Gene isoform. His research integrates issues of Basal lamina and Cell biology in his study of Endocrinology. His Laminin study incorporates themes from Perlecan, Immunology, Motor nerve, Fibroblast growth factor and NOD mice.
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Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development
Ernst Pöschl;Ursula Schlötzer-Schrehardt;Bent Brachvogel;Kenji Saito.
A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis
Y Li;D.A Lacerda;M.L Warman;D.R Beier.
Differential expression of two basement membrane collagen genes, COL4A6 and COL4A5, demonstrated by immunofluorescence staining using peptide-specific monoclonal antibodies.
Yoshifumi Ninomiya;Megumi Kagawa;Ken Ichi Iyama;Ichiro Naito.
Journal of Cell Biology (1995)
New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo.
Eric Petitclerc;Ariel Boutaud;Archie Prestayko;Jingsong Xu.
Journal of Biological Chemistry (2000)
Establishment by the rat lymph node method of epitope-defined monoclonal antibodies recognizing the six different α chains of human type IV collagen
Yoshikazu Sado;Megumi Kagawa;Yumiko Kishiro;Katsuyuki Sugihara.
Histochemistry and Cell Biology (1995)
Glomerular Basement Membrane IDENTIFICATION OF A NOVEL DISULFIDE-CROSS-LINKED NETWORK OF α3, α4, AND α5 CHAINS OF TYPE IV COLLAGEN AND ITS IMPLICATIONS FOR THE PATHOGENESIS OF ALPORT SYNDROME
Sripad Gunwar;Fernando Ballester;Milton E. Noelken;Yoshikazu Sado.
Journal of Biological Chemistry (1998)
Distinct Target-Derived Signals Organize Formation, Maturation, and Maintenance of Motor Nerve Terminals
Michael A. Fox;Joshua R. Sanes;Dorin Bogdan Borza;Veraragavan P. Eswarakumar.
Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome.
Roy Morello;Guang Zhou;Sandra D. Dreyer;Sandra D. Dreyer;Scott J. Harvey.
Nature Genetics (2001)
Compositional differences between infant and adult human corneal basement membranes.
Andrea Kabosova;Dimitri T. Azar;Gregory A. Bannikov;Kevin P. Campbell.
Investigative Ophthalmology & Visual Science (2007)
Basement membrane abnormalities in human eyes with diabetic retinopathy.
A V Ljubimov;R E Burgeson;R J Butkowski;J R Couchman.
Journal of Histochemistry and Cytochemistry (1996)
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