Lawrence B. Holzman

Overview

Best Publications

• Podocyte Depletion Causes Glomerulosclerosis: Diphtheria Toxin–Induced Podocyte Depletion in Rats Expressing Human Diphtheria Toxin Receptor Transgene

  Bryan L. Wharram;Meera Goyal;Jocelyn E. Wiggins;Silja K. Sanden

  818
  Citations

• Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin

  Karin Schwarz;Matias Simons;Jochen Reiser;Moin A. Saleem

  801
  Citations

• Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

  Bernward Hinkes;Roger C. Wiggins;Rasheed Gbadegesin;Christopher N. Vlangos

  647
  Citations

• mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

  Ken Inoki;Hiroyuki Mori;Junying Wang;Tsukasa Suzuki

  587
  Citations

• Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat

  Yeong Hoon Kim;Meera Goyal;David Kurnit;Bryan Wharram

  532
  Citations

• Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin.

  V M Dixit;S Green;V Sarma;L B Holzman

  502
  Citations

• Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

  Rakesh Verma;Iulia Kovari;Abdul Soofi;Deepak Nihalani

  476
  Citations

• Wnt/β-Catenin Signaling Promotes Podocyte Dysfunction and Albuminuria

  Chunsun Dai;Donna B. Stolz;Lawrence P. Kiss;Satdarshan P. Monga

  474
  Citations

• Podocyte-specific expression of cre recombinase in transgenic mice.

  Marcus J. Moeller;Silja K. Sanden;Abdulsalam Soofi;Roger C. Wiggins

  442
  Citations

• Nephrin localizes to the slit pore of the glomerular epithelial cell.

  Lawrence B. Holzman;Patricia L.S.T. John;Iulia A. Kovari;Rakesh Verma

  440
  Citations

• Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis

  Shaolin Shi;Liping Yu;Celine Chiu;Yezhou Sun

  432
  Citations

• Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein.

  James Turkson;Tammy Bowman;Jalila Adnane;Yi Zhang

  350
  Citations

• Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach

  Crystal A. Gadegbeku;Debbie S. Gipson;Lawrence B. Holzman;Akinlolu O. Ojo

  296
  Citations

• Fyn Binds to and Phosphorylates the Kidney Slit Diaphragm Component Nephrin

  Rakesh Verma;Bryan Wharram;Iulia Kovari;Robin Kunkel

  288
  Citations

• Nephrin and Neph1 Co-localize at the Podocyte Foot Process Intercellular Junction and Form cis Hetero-oligomers

  Gina Marie Barletta;Iulia A. Kovari;Rakesh K. Verma;Dontscho Kerjaschki

  277
  Citations

• KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for Glomerulonephritis

  Laurence H Beck;Andrew S Bomback;Michael J Choi;Larry B Holzman

  269
  Citations

• A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein.

  Lawrence B. Holzman;Rory M. Marks;Vishva M. Dixit

  259
  Citations

• Podocytes Populate Cellular Crescents in a Murine Model of Inflammatory Glomerulonephritis

  Marcus J. Moeller;Abdulsalaam Soofi;Inge Hartmann;Michel Le Hir

  256
  Citations

• Podocyte-Specific Deletion of Integrin-Linked Kinase Results in Severe Glomerular Basement Membrane Alterations and Progressive Glomerulosclerosis

  Chiraz El-Aouni;Nadja Herbach;Simone M. Blattner;Simone M. Blattner;Anna Henger;Anna Henger

  228
  Citations

• GLEPP1, a renal glomerular epithelial cell (podocyte) membrane protein-tyrosine phosphatase. Identification, molecular cloning, and characterization in rabbit.

  Peedikayil E. Thomas;Bryan L. Wharram;Meera Goyal;Jocelyn E. Wiggins

  228
  Citations