World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
118
Citations
48948
World Ranking
4073
National Ranking
2233

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Matthias Kretzler is affiliated with the University of Michigan-Ann Arbor in the United States. Their scholarly work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with considerable focus on Nephrology, Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, and Pulmonary and Respiratory Medicine. Research topics addressed include Renal Diseases and Glomerulopathies, Chronic Kidney Disease and Diabetes, Renal and related cancers, Single-cell and spatial transcriptomics, Diabetes Treatment and Management, Systemic Lupus Erythematosus Research, and Birth, Development, and Health.

Their publication record features multiple papers in notable venues, demonstrating engagement with the nephrology and medical science communities. Frequent publication venues incorporate:

  • Journal of the American Society of Nephrology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Kidney International
  • Kidney International Reports
  • JCI Insight

Among recent papers associated with Matthias Kretzler are:

  • "Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference," 2020, Kidney International
  • "Development and evaluation of deep learning-based segmentation of histologic structures in the kidney cortex with multiple histologic stains," 2020, Kidney International
  • "Rationale and design of the Kidney Precision Medicine Project," 2021, Kidney International
  • "Integrated multi-omics approaches to improve classification of chronic kidney disease," 2020, Nature Reviews Nephrology
  • "Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference," 2022, Kidney International

Frequent collaborators in their research include Viji Nair, Jeffrey B. Hodgin, Rajasree Menon, Sean Eddy, and Wenjun Ju. These collaborations reflect a network within the fields of nephrology and molecular biology, supporting contributions that span clinical and molecular investigations.

Matthias Kretzler's work centers on elucidating mechanisms and classifications related to kidney disease and related metabolic and systemic conditions, using advanced methodologies that include multi-omics and machine learning approaches to histologic analysis.

The scientist has been recognized as a member of the Association of American Physicians, highlighting their standing within the medical research community.

Best Publications

  • A reference panel of 64,976 haplotypes for genotype imputation

    Shane McCarthy;Sayantan Das;Warren Kretzschmar;Olivier Delaneau

  • Cell Biology of the Glomerular Podocyte

    Hermann Pavenstädt;Wilhelm Kriz;Matthias Kretzler

  • Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

    Eneida Villanueva;Srilakshmi Yalavarthi;Celine C. Berthier;Jeffrey B. Hodgin

  • Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition

    Debra F. Higgins;Kuniko Kimura;Wanja M. Bernhardt;Nikita Shrimanker

  • Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy

    Adeera Levin;Marcello Tonelli;Joseph Bonventre;Josef Coresh

  • Mouse Models of Diabetic Nephropathy

    Frank C. Brosius;Charles E. Alpers;Erwin P. Bottinger;Matthew D. Breyer

  • The immune cell landscape in kidneys of patients with lupus nephritis

    Arnon Arazi;Deepak A Rao;Celine C Berthier;Anne Davidson

  • Induction of B7-1 in podocytes is associated with nephrotic syndrome

    Jochen Reiser;Jochen Reiser;Gero Von Gersdorff;Martin Loos;Jun Oh

  • Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference.

    Andrew S. Levey;Kai-Uwe Eckardt;Nijsje M. Dorman;Stacy L. Christiansen

  • Modification of kidney barrier function by the urokinase receptor

    Changli Wei;Clemens C. Möller;Mehmet M. Altintas;Jing Li

  • mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

    Ken Inoki;Hiroyuki Mori;Junying Wang;Tsukasa Suzuki

  • The Glomerular Slit Diaphragm Is a Modified Adherens Junction

    Jochen Reiser;Wilhelm Kriz;Matthias Kretzler;Peter Mundel

  • Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

    Markus Gödel;Björn Hartleben;Nadja Herbach;Shuya Liu

  • Research capacity. Enabling the genomic revolution in Africa

    Charles Rotimi;Akin Abayomi;Alash'le Abimiku;Victoria May Adabayeri

  • Modular Activation of Nuclear Factor-κB Transcriptional Programs in Human Diabetic Nephropathy

    Holger Schmid;Anissa Boucherot;Anissa Boucherot;Yoshinari Yasuda;Anna Henger;Anna Henger

  • Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: A gene expression analysis on total and microdissected prostate tissue

    Thomas Ernst;Manfred Hergenhahn;Marc Kenzelmann;Clemens D. Cohen

  • High-Throughput Screening Enhances Kidney Organoid Differentiation From Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping

    Stefan M. Czerniecki;Nelly M. Cruz;Jennifer L. Harder;Rajasree Menon

  • From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy.

    Ying Qian;Eva Feldman;Subramanian Pennathur;Matthias Kretzler

  • Quantitative gene expression analysis in renal biopsies: A novel protocol for a high-throughput multicenter application

    Clemens D. Cohen;Karin Frach;Detlef Schlöndorff;Matthias Kretzler

  • Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker

    Wenjun Ju;Viji Nair;Shahaan Smith;Li Zhu

Frequent Co-Authors

Detlef Schlöndorff
Detlef Schlöndorff Icahn School of Medicine at Mount Sinai
Hermann Josef Gröne
Hermann Josef Gröne German Cancer Research Center
Hans-Joachim Anders
Hans-Joachim Anders Ludwig-Maximilians-Universität München
Robert G. Nelson
Robert G. Nelson National Institutes of Health
Lawrence B. Holzman
Lawrence B. Holzman University of Pennsylvania
Katherine R. Tuttle
Katherine R. Tuttle University of Washington
Wilhelm Kriz
Wilhelm Kriz Heidelberg University
Anne Davidson
Anne Davidson Feinstein Institute for Medical Research
Jeffrey B. Kopp
Jeffrey B. Kopp National Institutes of Health
Edgar A. Otto
Edgar A. Otto University of Michigan–Ann Arbor

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