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Medicine

D-Index
92
Citations
40958
World Ranking
11128
National Ranking
5727

Overview

Gerald B. Appel is affiliated with Columbia University in the United States and works primarily in the field of medicine, with a focus on nephrology. Their research interests span several subfields including genetics, molecular biology, immunology, and hematology. The main topics covered in their work include renal diseases and glomerulopathies, chronic kidney disease and diabetes, the complement system in diseases, platelet disorders and treatments, vasculitis and related conditions, cell adhesion molecules research, as well as renal and related cancers.

Their recent publications demonstrate a broad engagement with kidney-related research and its underlying molecular and genetic mechanisms. Notable papers include:

  • The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis (2020, Nature Communications)
  • Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial (2023, The Lancet)
  • Development and evaluation of deep learning-based segmentation of histologic structures in the kidney cortex with multiple histologic stains (2020, Kidney International)
  • Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy (2023, Nature Genetics)
  • A meta-analysis of GFR slope as a surrogate endpoint for kidney failure (2023, Nature Medicine)

Gerald B. Appel collaborates frequently with several researchers, including:

  • Andrew S. Bomback
  • Pietro A. Canetta
  • Jai Radhakrishnan
  • Maddalena Marasà
  • Fernando C. Fervenza

Their work has been published in multiple venues, reflecting a deep engagement with nephrology and kidney health research. Key publication venues where they have contributed extensively include:

  • Journal of the American Society of Nephrology
  • Kidney International Reports
  • Clinical Journal of the American Society of Nephrology
  • Kidney International
  • American Journal of Kidney Diseases

Best Publications

  • The Classification of Glomerulonephritis in Systemic Lupus Erythematosus Revisited

    Jan J. Weening;Vivette D. D'Agati;Melvin M. Schwartz;Surya V. Seshan

  • Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: The lupus nephritis assessment with rituximab study†

    Brad H. Rovin;Richard Furie;Kevin Latinis;R. John Looney

  • Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis

    Ellen M. Ginzler;Mary Anne Dooley;Cynthia Aranow;Mimi Y. Kim

  • Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis

    Gerald B. Appel;Gabriel Contreras;Mary Anne Dooley;Ellen M. Ginzler

  • Diagnostic Utility of Exome Sequencing for Kidney Disease

    Emily E Groopman;Maddalena Marasa;Sophia Cameron-Christie;Slavé Petrovski

  • Mycophenolate versus azathioprine as maintenance therapy for lupus nephritis

    Mary Anne Dooley;David Jayne;Ellen M. Ginzler;David Isenberg

  • Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

    Timothy H.J. Goodship;H. Terence Cook;Fadi Fakhouri;Fernando C. Fervenza

  • C3 glomerulopathy: consensus report

    Matthew C. Pickering;Vivette D. D'agati;Carla M. Nester;Richard J. Smith

  • Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens

    Krzysztof Kiryluk;Yifu Li;Francesco Scolari;Simone Sanna-Cherchi

  • Randomized Trial of an Inhibitor of Formation of Advanced Glycation End Products in Diabetic Nephropathy

    W. Kline Bolton;Daniel C. Cattran;Mark E. Williams;Sharon G. Adler

  • Collapsing Focal Segmental Glomerulosclerosis Following Treatment with High-Dose Pamidronate

    Glen S. Markowitz;Gerald B. Appel;Paul L. Fine;Andrew Z. Fenves

  • Pathology of HIV-associated nephropathy: a detailed morphologic and comparative study.

    Vivette D'Agati;Jung-Il Suh;Laura Carbone;Jen-Tse Cheng

  • Membranoproliferative Glomerulonephritis Type II (Dense Deposit Disease): An Update

    Gerald B. Appel;H. Terence Cook;Gregory Hageman;J. Charles Jennette

  • Renal monoclonal immunoglobulin deposition disease : The disease spectrum

    Julie Lin;Glen S. Markowitz;Anthony M. Valeri;Neeraja Kambham

  • Cyclosporine in patients with steroid-resistant membranous nephropathy: a randomized trial.

    Daniel C. Cattran;Gerald B. Appel;Lee A. Hebert;Lawrence G. Hunsicker

  • Adult Minimal-Change Disease: Clinical Characteristics, Treatment, and Outcomes

    Meryl Waldman;R. John Crew;Anthony Valeri;Joshua Busch

  • Rituximab or Cyclosporine in the Treatment of Membranous Nephropathy

    Fernando C. Fervenza;Gerald B. Appel;Sean J. Barbour;Brad H. Rovin

  • Eculizumab for Dense Deposit Disease and C3 Glomerulonephritis

    Andrew S. Bomback;Richard J. Smith;Gaetano R. Barile;Yuzhou Zhang

  • Proliferative Glomerulonephritis with Monoclonal IgG Deposits

    Samih H. Nasr;Anjali Satoskar;Glen S. Markowitz;Anthony M. Valeri

  • ATYPICAL HEMOLYTIC UREMIC SYNDROME AND C3 GLOMERULOPATHY: CONCLUSIONS FROM A «KIDNEY DISEASE: IMPROVING GLOBAL OUTCOMES» (KDIGO) CONTROVERSIES CONFERENCE

    Timothy H.J. Goodship;H. Terence Cook;Fadi Fakhouri;Fernando C. Fervenza

Frequent Co-Authors

Vivette D. D'Agati
Vivette D. D'Agati Columbia University
Glen S. Markowitz
Glen S. Markowitz Columbia University
Harold C. Neu
Harold C. Neu Columbia University
Martin R. Pollak
Martin R. Pollak Beth Israel Deaconess Medical Center
Daniel C. Cattran
Daniel C. Cattran University Health Network
Ali G. Gharavi
Ali G. Gharavi Columbia University
Ellen M. Ginzler
Ellen M. Ginzler SUNY Downstate Medical Center
Lawrence B. Holzman
Lawrence B. Holzman University of Pennsylvania
J. Charles Jennette
J. Charles Jennette University of North Carolina at Chapel Hill

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