Ruth Halaban

Overview

Best Publications

• Genomic Classification of Cutaneous Melanoma

  Rehan Akbani;Kadir C. Akdemir;B. Arman Aksoy;Monique Albert

  3009
  Citations

• Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

  Michael Krauthammer;Yong Lin Kong;Byung Hak Ha;Perry Evans

  1330
  Citations

• In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma

  Florian A. Karreth;Yvonne Tay;Daniele Perna;Ugo Ala;Ugo Ala

  746
  Citations

• Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.

  R Halaban;R Langdon;N Birchall;C Cuono

  637
  Citations

• Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas.

  Keith S Hoek;David L Rimm;Kenneth R Williams;Hongyu Zhao

  604
  Citations

• Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus.

  Byoung S. Kwon;Asifa K. Haq;Seymour H. Pomerantz;Ruth Halaban

  588
  Citations

• Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure

  Sanjay Premi;Silvia Wallisch;Camila M. Mano;Adam B. Weiner

  580
  Citations

• Combination Therapy with Anti–CTLA-4 and Anti–PD-1 Leads to Distinct Immunologic Changes In Vivo

  Rituparna Das;Rakesh Verma;Mario Sznol;Chandra Sekhar Boddupalli

  508
  Citations

• Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas

  Michael Krauthammer;Yong Kong;Antonella Bacchiocchi;Perry Evans

  423
  Citations

• VEGF121, a vascular endothelial growth factor (VEGF) isoform lacking heparin binding ability, requires cell-surface heparan sulfates for efficient binding to the VEGF receptors of human melanoma cells

  Tzafra Cohen;Hela Gitay-Goren;Rivka Sharon;Masabumi Shibuya

  413
  Citations

• Changes in serum interleukin-8 (IL-8) levels reflect and predict response to anti-PD-1 treatment in melanoma and non-small-cell lung cancer patients.

  M. F. Sanmamed;J. L. Perez-Gracia;K. A. Schalper;J. P. Fusco

  407
  Citations

• UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in Cockayne syndrome cells

  David B. Bregman;David B. Bregman;Ruth Halaban;Alain J. Van Gool;Karla A. Henning;Karla A. Henning

  399
  Citations

• Integrated NY-ESO-1 antibody and CD8+ T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab

  Jianda Yuan;Matthew Adamow;Brian A. Ginsberg;Teresa S. Rasalan

  395
  Citations

• PLX4032, a selective BRAFV600E kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAFWT melanoma cells

  Ruth Halaban;Wengeng Zhang;Antonella Bacchiocchi;Elaine Cheng

  390
  Citations

• Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells

  Ruth Halaban;Elaine Cheng;Yuhua Zhang;Gisela Moellmann

  357
  Citations

• Regulation of tyrosinase in human melanocytes grown in culture.

  R Halaban;S H Pomerantz;S Marshall;D T Lambert

  355
  Citations

• bFGF as an autocrine growth factor for human melanomas.

  R Halaban;B S Kwon;S Ghosh;P Delli Bovi

  345
  Citations

• Early B cell changes predict autoimmunity following combination immune checkpoint blockade

  Rituparna Das;Noffar Bar;Michelle Ferreira;Aaron M. Newman

  334
  Citations

• bFGF is the putative natural growth factor for human melanocytes.

  Ruth Halaban;Sikha Ghosh;Andrew Baird

  330
  Citations

• Altered metabolism of mast-cell growth factor (c-kit ligand) in cutaneous mastocytosis.

  B. J. Longley;G. S. Morganroth;L. Tyrrell;Tie Gang Ding

  325
  Citations