Lester Kobzik mainly investigates Immunology, Inflammation, Internal medicine, Endocrinology and Lung injury. His biological study spans a wide range of topics, including Receptor and Bronchoalveolar lavage, Lung. His Receptor study combines topics in areas such as Molecular biology and Computational biology.
His Inflammation research is multidisciplinary, incorporating perspectives in Toxicity, Oxidative stress, Innate immune system and Pharmacology. His work in the fields of Internal medicine, such as Heart failure, Hypoxia, Ventricular pressure and TUNEL assay, intersects with other areas such as Heme oxygenase. His Endocrinology study which covers Agonist that intersects with Muscarinic acetylcholine receptor, Sodium nitroprusside and Patch clamp.
His scientific interests lie mostly in Immunology, Lung, Internal medicine, Inflammation and Molecular biology. His studies in Immunology integrate themes in fields like Receptor, Bronchoalveolar lavage and Macrophage. His work is dedicated to discovering how Lung, Pathology are connected with Ischemia and other disciplines.
In Internal medicine, Lester Kobzik works on issues like Endocrinology, which are connected to Thromboxane and Respiratory system. His Inflammation research includes themes of Lipopolysaccharide, Immune system and Cytokine. The study incorporates disciplines such as Respiratory burst, Cell culture and Intracellular in addition to Molecular biology.
His main research concerns Immunology, Inflammation, Macrophage, Cell biology and Lung. Particularly relevant to Tumor necrosis factor alpha is his body of work in Immunology. His research on Inflammation also deals with topics like
As a part of the same scientific family, Lester Kobzik mostly works in the field of Macrophage, focusing on Innate immune system and, on occasion, Phagocytosis and Virology. Lester Kobzik combines subjects such as Autophagy, Molecular biology, Regulation of gene expression and Borrelia burgdorferi with his study of Cell biology. The concepts of his Lung study are interwoven with issues in Apoptosis, COPD and Bone marrow.
His primary scientific interests are in Immunology, Lung, Innate immune system, Inflammation and Receptor. His Immunology study integrates concerns from other disciplines, such as Offspring, DNA methylation, Pneumonia, Signal transduction and Lung injury. His Lung research is multidisciplinary, incorporating elements of COPD, Airway and Bone marrow.
His Innate immune system study also includes
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Nitric oxide in skeletal muscle
Lester Kobzik;Michael B. Reid;David S. Bredt;Jonathan S. Stamler.
An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation : I. The roles of minor H antigens and endotoxin
Kenneth R. Cooke;Lester Kobzik;Thomas R. Martin;Joanne Brewer.
Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization.
L. Kobzik;D. S. Bredt;C. J. Lowenstein;J. Drazen.
American Journal of Respiratory Cell and Molecular Biology (1993)
Endothelial Nitric Oxide Synthase Targeting to Caveolae: SPECIFIC INTERACTIONS WITH CAVEOLIN ISOFORMS IN CARDIAC MYOCYTES AND ENDOTHELIAL CELLS *
Olivier Feron;Laurent Belhassen;Lester Kobzik;Thomas W. Smith.
Journal of Biological Chemistry (1996)
Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium
Stefan Frantz;Lester Kobzik;Young-Dae Kim;Ryuji Fukazawa.
Journal of Clinical Investigation (1999)
Reduced Myocardial Ischemia-Reperfusion Injury in Toll-Like Receptor 4-Deficient Mice
Jun-ichi Oyama;Charles Blais;Xiaoli Liu;Minying Pu.
Reactive oxygen in skeletal muscle. I. Intracellular oxidant kinetics and fatigue in vitro.
M. B. Reid;K. E. Haack;K. M. Franchek;P. A. Valberg.
Journal of Applied Physiology (1992)
Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium.
Jean-Luc Balligand;D Ungureanu;R A Kelly;L Kobzik.
Journal of Clinical Investigation (1993)
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.
C Gauthier;V Leblais;L Kobzik;J N Trochu.
Journal of Clinical Investigation (1998)
Reciprocal Rb Inactivation and p16INK4 Expression in Primary Lung Cancers and Cell Lines
Geoffrey I. Shapiro;Christian D. Edwards;Lester Kobzik;John Godleski.
Cancer Research (1995)
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