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D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
8452
World Ranking
16812
National Ranking
6936

Overview

David L. Perkins is affiliated with the University of New Mexico in the United States. Their primary research contributions are within the field of Medicine, with a focus on various subfields including Physiology, Immunology, Molecular Biology, Infectious Diseases, and Pulmonary and Respiratory Medicine.

The scientist's work covers several main topics, among which are sarcoidosis and beryllium toxicity research, gut microbiota and health, asthma and respiratory diseases, diet and metabolism studies, immune cell function and interaction, and SARS-CoV-2 and COVID-19 research. They have published extensively on these subjects, reflecting a broad investigative scope.

Recent published papers by Perkins include the following:

  • Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies, 2021, Gut
  • Long non-coding RNAs (lncRNAs) NEAT1 and MALAT1 are differentially expressed in severe COVID-19 patients: An integrated single-cell analysis, 2022, PLoS ONE
  • The olfactory G protein-coupled receptor (Olfr-78/OR51E2) modulates the intestinal response to colitis, 2020, American Journal of Physiology-Cell Physiology
  • Obesity Management and Chronic Kidney Disease, 2021, Seminars in Nephrology
  • Healthful eating patterns, serum metabolite profile and risk of diabetes in a population-based prospective study of US Hispanics/Latinos, 2022, Diabetologia

Frequent co-authors who have collaborated with Perkins include Patricia W. Finn, Christian Ascoli, Christen Vagts, Huang Kai, and Benjamin A. Turturice. These partnerships underline a network of scientific cooperation that supports the breadth of Perkins's research outputs.

Key journals and publication venues where Perkins has contributed multiple articles are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Transplantation
  • eLife
  • Hydrobiologia
  • Frontiers in Medicine

The combination of published work and collaborations indicates a research profile centered on multidisciplinary approaches within medical sciences. The research spans molecular to clinical levels, encompassing both mechanistic studies and population health investigations related to critical issues such as metabolism, immune response, and respiratory diseases including COVID-19.

Best Publications

  • Analysis of the microbiome: Advantages of whole genome shotgun versus 16S amplicon sequencing

    Ravi Ranjan;Asha Rani;Ahmed Metwally;Halvor S. McGee

  • Elastin fragments drive disease progression in a murine model of emphysema

    A. McGarry Houghton;Pablo A. Quintero;David L. Perkins;Dale K. Kobayashi

  • Chronic caregiver stress and IgE expression, allergen-induced proliferation, and cytokine profiles in a birth cohort predisposed to atopy

    Rosalind J. Wright;Patricia Finn;Johanna Paola Contreras;Sheldon Cohen

  • Regulation of CTLA-4 expression during T cell activation.

    David Perkins;Zemin Wang;Carolyn Donovan;Hongzhen He

  • Toll-like receptor 4 or 2 agonists decrease allergic inflammation

    German Velasco;Monica Campo;Oscar J. Manrique;Abdelouahab Bellou

  • Fas Modulation of Apoptosis during Negative Selection of Thymocytes

    Januario E. Castro;Januario E. Castro;James A. Listman;James A. Listman;Bruce A. Jacobson;Yunsheng Wang;Yunsheng Wang

  • Rituximab in the treatment of refractory pulmonary sarcoidosis

    Nadera Sweiss;Elyse E. Lower;Mehdi Mirsaeidi;Steven M. Dudek

  • NF-kappa B/Rel transcription factors: c-Rel promotes airway hyperresponsiveness and allergic pulmonary inflammation.

    Carolyn E. Donovan;David A. Mark;Hong Zhen He;Hsiou Chi Liou

  • Inhibition of T Cell Costimulation Abrogates Airway Hyperresponsiveness in a Murine Model

    S J Krinzman;G T De Sanctis;M Cernadas;D Mark

  • Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies

    Qibin Qi;Qibin Qi;Jun Li;Bing Yu;Jee Young Moon

  • Hubs in biological interaction networks exhibit low changes in expression in experimental asthma.

    Xin Lu;Vipul V Jain;Patricia W Finn;David L Perkins

  • Costimulatory molecule OX40L is critical for both Th1 and Th2 responses in allergic inflammation

    Ruth S. S. Arestides;Hongzhen He;Robert M. Westlake;Andrew I. Chen

  • Timing of IFN-β Exposure during Human Dendritic Cell Maturation and Naive Th Cell Stimulation Has Contrasting Effects on Th1 Subset Generation: A Role for IFN-β-Mediated Regulation of IL-12 Family Cytokines and IL-18 in Naive Th Cell Differentiation

    Taro Nagai;Odile Devergne;Thomas F. Mueller;David L. Perkins

  • Tocilizumab in the treatment of rheumatoid arthritis and beyond

    Anjali Shetty;Rebekah Hanson;Peter Korsten;Munir Shawagfeh

  • Analysis of robust innate immune response after transplantation in the absence of adaptive immunity.

    Hongzhen He;James R. Stone;David L. Perkins

  • Synergistic Induction of CTLA-4 Expression by Costimulation with TCR Plus CD28 Signals Mediated by Increased Transcription and Messenger Ribonucleic Acid Stability

    Patrick W. Finn;Hougzhen He;Yungsherg Wang;Zemin Wang

  • Pertussis toxin prevents the induction of peripheral T cell anergy and enhances the T cell response to an encephalitogenic peptide of myelin basic protein.

    Thomas Kamradt;Paul D. Soloway;David L. Perkins;Malcolm L. Gefter

  • Children at risk for asthma: Home allergen levels, lymphocyte proliferation, and wheeze

    Patricia W. Finn;Jacques O. Boudreau;Hongzhen He;Yunsheng Wang

  • Graft produced interleukin-6 functions as a danger signal and promotes rejection after transplantation.

    Yurong Liang;Kenneth Christopher;Patricia W. Finn;Yolonda L. Colson

  • Immunodominance: intramolecular competition between T cell epitopes.

    David L. Perkins;Gabriel Berriz;Thomas Kamradt;John A. Smith

Frequent Co-Authors

Patricia W. Finn
Patricia W. Finn University of Illinois at Chicago
Diane R. Gold
Diane R. Gold Harvard University
Scott T. Weiss
Scott T. Weiss Harvard University
Emily Oken
Emily Oken Harvard University
Augusto A. Litonjua
Augusto A. Litonjua University of Rochester Medical Center
Matthew W. Gillman
Matthew W. Gillman National Institutes of Health
John A. Smith
John A. Smith University of Alabama at Birmingham
Lester Kobzik
Lester Kobzik Harvard University
David C. Christiani
David C. Christiani Harvard University

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