Jianguo Gu mainly investigates Cell biology, Cell migration, Integrin, Biochemistry and Cancer research. His study on Cell biology is mostly dedicated to connecting different topics, such as Cell adhesion. His work is dedicated to discovering how Biochemistry, Cell culture are connected with Molecular biology and Acetylglucosamine and other disciplines.
Many of his research projects under Molecular biology are closely connected to Library with Library, tying the diverse disciplines of science together. His Cancer research research includes elements of Internal medicine, Endocrinology and PTEN. The PTEN study combines topics in areas such as Gastrointestinal tract and Focal adhesion.
Jianguo Gu mostly deals with Cell biology, Integrin, Molecular biology, Biochemistry and Cell adhesion. His Cell biology study combines topics in areas such as Cell, Cell migration and Cell growth. His Integrin research incorporates themes from Laminin, Fibronectin, Cancer research and Glycosylation.
His Cancer research research includes themes of Cancer, Metastasis, Downregulation and upregulation, Phosphorylation and PTEN. His work focuses on many connections between Molecular biology and other disciplines, such as Cell culture, that overlap with his field of interest in Carcinogenesis. His study in Cell adhesion is interdisciplinary in nature, drawing from both Cadherin, N-linked glycosylation, Focal adhesion, Cancer cell and Cell adhesion molecule.
His scientific interests lie mostly in Fucosylation, Cell biology, Fucosyltransferase, Molecular biology and Cell. His Fucosylation research is multidisciplinary, relying on both Enzyme assay, Cancer research, T cell, Blot and Cytotoxic T cell. His Cell biology study combines topics from a wide range of disciplines, such as Cell morphology, Integrin and Cell adhesion.
His Cell adhesion research is multidisciplinary, incorporating perspectives in Epithelial–mesenchymal transition, Cell migration, N-linked glycosylation, Focal adhesion and Cancer cell. His work carried out in the field of Molecular biology brings together such families of science as B cell, Glycosyltransferase, Substrate, Enzyme and Messenger RNA. His work deals with themes such as Cell culture and Cell growth, which intersect with Cell.
His main research concerns Cell biology, Fucosyltransferase, Fucosylation, Signal transduction and Oxidative stress. He interconnects Cell, Integrin, Cell migration and Cell adhesion in the investigation of issues within Cell biology. The concepts of his Integrin study are interwoven with issues in Fibronectin, Cytoplasm and Focal adhesion.
His work investigates the relationship between Cell adhesion and topics such as Golgi apparatus that intersect with problems in Cancer cell. His Fucosylation study results in a more complete grasp of Molecular biology. In Signal transduction, Jianguo Gu works on issues like Malignant transformation, which are connected to Protein kinase B.
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Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
Masahito Tamura;Jianguo Gu;Jianguo Gu;Kazue Matsumoto;Kazue Matsumoto;Shin-ichi Aota;Shin-ichi Aota.
Science (1998)
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
Katrina Podsypanina;Lora Hedrick Ellenson;Adriana Nemes;Jianguo Gu.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Shc and Fak Differentially Regulate Cell Motility and Directionality Modulated by Pten
Jianguo Gu;Masahito Tamura;Roumen Pankov;Erik H.J. Danen.
Journal of Cell Biology (1999)
Tumor Suppressor PTEN Inhibition of Cell Invasion, Migration, and Growth: Differential Involvement of Focal Adhesion Kinase and p130Cas
Masahito Tamura;Jianguo Gu;Takahisa Takino;Kenneth M. Yamada.
Cancer Research (1999)
PTEN Interactions with Focal Adhesion Kinase and Suppression of the Extracellular Matrix-dependent Phosphatidylinositol 3-Kinase/Akt Cell Survival Pathway *
Masahito Tamura;Jianguo Gu;Erik H.J. Danen;Takahisa Takino.
Journal of Biological Chemistry (1999)
Tumor Suppressor PTEN Inhibits Integrin- and Growth Factor–mediated Mitogen-activated Protein (MAP) Kinase Signaling Pathways
Jianguo Gu;Masahito Tamura;Kenneth M. Yamada.
Journal of Cell Biology (1998)
Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice
Xiangchun Wang;Shinya Inoue;Jianguo Gu;Eiji Miyoshi.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Functional roles of N-glycans in cell signaling and cell adhesion in cancer.
Yan-Yang Zhao;Motoko Takahashi;Jian-Guo Gu;Eiji Miyoshi.
Cancer Science (2008)
Fucosylated haptoglobin is a novel marker for pancreatic cancer : A detailed analysis of the oligosaccharide structure and a possible mechanism for fucosylation
Noriko Okuyama;Yoshihito Ide;Miyako Nakano;Tsutomu Nakagawa.
International Journal of Cancer (2006)
Core Fucosylation Regulates Epidermal Growth Factor Receptor-mediated Intracellular Signaling
Xiangchun Wang;Jianguo Gu;Hideyuki Ihara;Eiji Miyoshi.
Journal of Biological Chemistry (2006)
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