D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 15,003 155 World Ranking 6963 National Ranking 489

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Biochemistry

Jianguo Gu mainly investigates Cell biology, Cell migration, Integrin, Biochemistry and Cancer research. His study on Cell biology is mostly dedicated to connecting different topics, such as Cell adhesion. His work is dedicated to discovering how Biochemistry, Cell culture are connected with Molecular biology and Acetylglucosamine and other disciplines.

Many of his research projects under Molecular biology are closely connected to Library with Library, tying the diverse disciplines of science together. His Cancer research research includes elements of Internal medicine, Endocrinology and PTEN. The PTEN study combines topics in areas such as Gastrointestinal tract and Focal adhesion.

His most cited work include:

  • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN (1074 citations)
  • Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems (863 citations)
  • Shc and Fak Differentially Regulate Cell Motility and Directionality Modulated by Pten (369 citations)

What are the main themes of his work throughout his whole career to date?

Jianguo Gu mostly deals with Cell biology, Integrin, Molecular biology, Biochemistry and Cell adhesion. His Cell biology study combines topics in areas such as Cell, Cell migration and Cell growth. His Integrin research incorporates themes from Laminin, Fibronectin, Cancer research and Glycosylation.

His Cancer research research includes themes of Cancer, Metastasis, Downregulation and upregulation, Phosphorylation and PTEN. His work focuses on many connections between Molecular biology and other disciplines, such as Cell culture, that overlap with his field of interest in Carcinogenesis. His study in Cell adhesion is interdisciplinary in nature, drawing from both Cadherin, N-linked glycosylation, Focal adhesion, Cancer cell and Cell adhesion molecule.

He most often published in these fields:

  • Cell biology (50.62%)
  • Integrin (31.48%)
  • Molecular biology (31.48%)

What were the highlights of his more recent work (between 2017-2021)?

  • Fucosylation (25.31%)
  • Cell biology (50.62%)
  • Fucosyltransferase (15.43%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Fucosylation, Cell biology, Fucosyltransferase, Molecular biology and Cell. His Fucosylation research is multidisciplinary, relying on both Enzyme assay, Cancer research, T cell, Blot and Cytotoxic T cell. His Cell biology study combines topics from a wide range of disciplines, such as Cell morphology, Integrin and Cell adhesion.

His Cell adhesion research is multidisciplinary, incorporating perspectives in Epithelial–mesenchymal transition, Cell migration, N-linked glycosylation, Focal adhesion and Cancer cell. His work carried out in the field of Molecular biology brings together such families of science as B cell, Glycosyltransferase, Substrate, Enzyme and Messenger RNA. His work deals with themes such as Cell culture and Cell growth, which intersect with Cell.

Between 2017 and 2021, his most popular works were:

  • Core Fucosylation of the T Cell Receptor Is Required for T Cell Activation. (23 citations)
  • Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation (21 citations)
  • Fucoidan Alleviates Acetaminophen-Induced Hepatotoxicity via Oxidative Stress Inhibition and Nrf2 Translocation (21 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Biochemistry

His main research concerns Cell biology, Fucosyltransferase, Fucosylation, Signal transduction and Oxidative stress. He interconnects Cell, Integrin, Cell migration and Cell adhesion in the investigation of issues within Cell biology. The concepts of his Integrin study are interwoven with issues in Fibronectin, Cytoplasm and Focal adhesion.

His work investigates the relationship between Cell adhesion and topics such as Golgi apparatus that intersect with problems in Cancer cell. His Fucosylation study results in a more complete grasp of Molecular biology. In Signal transduction, Jianguo Gu works on issues like Malignant transformation, which are connected to Protein kinase B.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

Masahito Tamura;Jianguo Gu;Jianguo Gu;Kazue Matsumoto;Kazue Matsumoto;Shin-ichi Aota;Shin-ichi Aota.
Science (1998)

1736 Citations

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

Katrina Podsypanina;Lora Hedrick Ellenson;Adriana Nemes;Jianguo Gu.
Proceedings of the National Academy of Sciences of the United States of America (1999)

1196 Citations

Shc and Fak Differentially Regulate Cell Motility and Directionality Modulated by Pten

Jianguo Gu;Masahito Tamura;Roumen Pankov;Erik H.J. Danen.
Journal of Cell Biology (1999)

577 Citations

Tumor Suppressor PTEN Inhibition of Cell Invasion, Migration, and Growth: Differential Involvement of Focal Adhesion Kinase and p130Cas

Masahito Tamura;Jianguo Gu;Takahisa Takino;Kenneth M. Yamada.
Cancer Research (1999)

511 Citations

PTEN Interactions with Focal Adhesion Kinase and Suppression of the Extracellular Matrix-dependent Phosphatidylinositol 3-Kinase/Akt Cell Survival Pathway *

Masahito Tamura;Jianguo Gu;Erik H.J. Danen;Takahisa Takino.
Journal of Biological Chemistry (1999)

509 Citations

Tumor Suppressor PTEN Inhibits Integrin- and Growth Factor–mediated Mitogen-activated Protein (MAP) Kinase Signaling Pathways

Jianguo Gu;Masahito Tamura;Kenneth M. Yamada.
Journal of Cell Biology (1998)

457 Citations

Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

Xiangchun Wang;Shinya Inoue;Jianguo Gu;Eiji Miyoshi.
Proceedings of the National Academy of Sciences of the United States of America (2005)

433 Citations

Functional roles of N-glycans in cell signaling and cell adhesion in cancer.

Yan-Yang Zhao;Motoko Takahashi;Jian-Guo Gu;Eiji Miyoshi.
Cancer Science (2008)

402 Citations

Fucosylated haptoglobin is a novel marker for pancreatic cancer : A detailed analysis of the oligosaccharide structure and a possible mechanism for fucosylation

Noriko Okuyama;Yoshihito Ide;Miyako Nakano;Tsutomu Nakagawa.
International Journal of Cancer (2006)

334 Citations

Core Fucosylation Regulates Epidermal Growth Factor Receptor-mediated Intracellular Signaling

Xiangchun Wang;Jianguo Gu;Hideyuki Ihara;Eiji Miyoshi.
Journal of Biological Chemistry (2006)

323 Citations

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