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D-Index
86
Citations
63427
World Ranking
13834
National Ranking
7020

Overview

Ramon Parsons is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research spans fields within Biochemistry, Genetics and Molecular Biology as well as Medicine, with a significant focus on molecular mechanisms related to cancer and related diseases.

Their subfields of study mainly include Molecular Biology, Oncology, Immunology, Cancer Research, and Hematology. These areas correspond to their research output which covers diverse topics such as Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, Epigenetics and DNA Methylation, Cancer-related Molecular Pathways, PI3K/AKT/mTOR signaling in cancer, Cancer Immunotherapy and Biomarkers, and Multiple Myeloma Research and Treatments.

Frequent publication venues for Ramon Parsons include:

  • Journal of Medicinal Chemistry
  • Cancer Research
  • Cell Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications

Some of the recent papers authored or co-authored by Ramon Parsons are:

  • "Cooperation Between Distinct Cancer Driver Genes Underlies Intertumor Heterogeneity in Hepatocellular Carcinoma" (2020), published in Gastroenterology
  • "Blood-brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system" (2025), published in Nature Materials
  • "Molecular mechanisms in colitis-associated colorectal cancer" (2023), published in Oncogenesis
  • "PIK3CA and p53 Mutations Promote 4NQO-Initated Head and Neck Tumor Progression and Metastasis in Mice" (2020), published in Molecular Cancer Research
  • "Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders" (2021), published in Journal of Medicinal Chemistry

Ramon Parsons has collaborated frequently with various researchers, including:

  • Tiphaine Martin
  • Royce Zhou
  • Jian Jin
  • Kaitlyn Bosch
  • Dan Hasson

Best Publications

  • WAF1, a potential mediator of p53 tumor suppression

    Wafik S. El-Deiry;Takashi Tokino;Victor E. Velculescu;Daniel B. Levy

  • PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

    Jing Li;Clifford Yen;Danny Liaw;Katrina Podsypanina

  • Inactivation of the Type II TGF-β Receptor in Colon Cancer Cells with Microsatellite Instability

    Sanford D Markowitz;Jing Wang;Lois Myeroff;Ramon Parsons

  • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

    Fredrick S. Leach;Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu

  • Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

    D. Liaw;D. J. Marsh;J. Li;P. L M Dahia

  • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

    Masahito Tamura;Jianguo Gu;Jianguo Gu;Kazue Matsumoto;Kazue Matsumoto;Shin-ichi Aota;Shin-ichi Aota

  • The Molecular Basis of Turcot's Syndrome

    Stanley R. Hamilton;bo Liu;Ramon E. Parsons;Nickolas Papadopoulos

  • Hypermutability and mismatch repair deficiency in RER+ tumor cells

    Ramon Parsons;Guo Min Li;Matthew J. Longley;Woei horng Fang;Woei horng Fang

  • Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

    Katrina Podsypanina;Lora Hedrick Ellenson;Adriana Nemes;Jianguo Gu

  • Analysis of mismatch repair genes in hereditary non–polyposis colorectal cancer patients

    Bo Liu;Ramon Parsons;Nickolas Papadopoulos;Nicholas C. Nicolaides

  • P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

    Michael P. Myers;Javor P. Stolarov;Charis Eng;Jing Li

  • PIK3CA Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma

    Lao H. Saal;Karolina Holm;Matthew Maurer;Lorenzo Memeo

  • Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

    Teresa Palomero;Maria Luisa Sulis;Maria Cortina;Pedro J Real

  • Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer

    Ramon Parsons;Lois L. Myeroff;Bo Liu;James K. V. Willson

  • Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

    Bo Liu;Nicholas C. Nicolaides;Sanford Markowitz;James K.V. Willson

  • Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies.

    Hironori Tashiro;Marian S. Blazes;Rong Wu;Kathleen R. Cho

  • PTEN: life as a tumor suppressor.

    Laura Simpson;Ramon Parsons

  • Mutation Spectrum and Genotype-Phenotype Analyses in Cowden Disease and Bannayan-Zonana Syndrome, Two Hamartoma Syndromes With Germline PTEN Mutation

    Debbie J. Marsh;Valérie Coulon;Kathryn L. Lunetta;Philippe Rocca-Serra

  • Germline mutations in PTEN are present in Bannayan-Zonana syndrome.

    Debbie J. Marsh;Patricia L. M. Dahia;Zimu Zheng;Danny Liaw

  • An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/− mice

    Katrina Podsypanina;Richard T. Lee;Chris Politis;Ian Hennessy

Frequent Co-Authors

Hanina Hibshoosh
Hanina Hibshoosh Columbia University
Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Kenneth W. Kinzler
Kenneth W. Kinzler Johns Hopkins University
Charis Eng
Charis Eng Cleveland Clinic Lerner College of Medicine
Sanford D. Markowitz
Sanford D. Markowitz Case Western Reserve University
James K V Willson
James K V Willson The University of Texas at Dallas
Stanley R. Hamilton
Stanley R. Hamilton City Of Hope National Medical Center
Nickolas Papadopoulos
Nickolas Papadopoulos Johns Hopkins University School of Medicine
Vundavalli V. Murty
Vundavalli V. Murty Columbia University Medical Center
Albert de la Chapelle
Albert de la Chapelle The Ohio State University

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