D-Index & Metrics Best Publications
Frank Buchholz

Frank Buchholz

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 54 Citations 14,024 128 World Ranking 3165 National Ranking 217

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genome

Frank Buchholz mostly deals with Genetics, RNA interference, Gene, Cell biology and Gene silencing. Genetics and Computational biology are frequently intertwined in his study. His RNA interference research integrates issues from False positive paradox and Bioinformatics.

The study incorporates disciplines such as Mitosis and Viral replication in addition to Gene. The Cell biology study which covers Gene expression profiling that intersects with Stem cell, Embryonic stem cell and Chromatin immunoprecipitation. His Gene silencing study combines topics from a wide range of disciplines, such as RNA and Small interfering RNA.

His most cited work include:

  • A new logic for DNA engineering using recombination in Escherichia coli (1124 citations)
  • High-efficiency deleter mice show that FLPe is an alternative to Cre- loxP (993 citations)
  • A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances (744 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Genetics, RNA interference, Recombinase and Computational biology. Frank Buchholz combines subjects such as Embryonic stem cell, Cell, Cell division and Molecular biology with his study of Cell biology. His studies in Molecular biology integrate themes in fields like Gene expression, Transgene and Fusion protein.

His biological study spans a wide range of topics, including Gene silencing, Gene knockdown and Small interfering RNA. His work deals with themes such as Virology, Genome, Long terminal repeat, Provirus and DNA, which intersect with Recombinase. His Computational biology research includes elements of Genome editing, Rna protein and Functional genomics.

He most often published in these fields:

  • Cell biology (40.72%)
  • Genetics (32.58%)
  • RNA interference (23.53%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (40.72%)
  • Internal medicine (13.12%)
  • Oncology (13.12%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Cell biology, Internal medicine, Oncology, Gene and Recombinase. His work carried out in the field of Cell biology brings together such families of science as Embryonic stem cell, RNA interference, Cell culture and DNA damage. Many of his research projects under Internal medicine are closely connected to Head and neck squamous-cell carcinoma with Head and neck squamous-cell carcinoma, tying the diverse disciplines of science together.

His work on Cell cycle and Enhancer as part of general Gene research is frequently linked to Context, bridging the gap between disciplines. He has researched Recombinase in several fields, including Genome editing, Genome, Genome engineering, DNA and Computational biology. Genome is a subfield of Genetics that Frank Buchholz tackles.

Between 2015 and 2021, his most popular works were:

  • The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. (99 citations)
  • The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. (99 citations)
  • Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity (81 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genome

Frank Buchholz spends much of his time researching Cell biology, DNA, Genetics, Retrospective cohort study and Oncology. His research integrates issues of Spindle apparatus, Cell division, Embryonic stem cell and Cell polarity in his study of Cell biology. His DNA study integrates concerns from other disciplines, such as Recombinase and Genome.

He integrates Genetics with CST complex in his research. The concepts of his Retrospective cohort study study are interwoven with issues in Cancer stem cell, Cancer and CD44. Frank Buchholz interconnects Clinical endpoint, Proportional hazards model and Pathology in the investigation of issues within Oncology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A new logic for DNA engineering using recombination in Escherichia coli

Youming Zhang;F. Buchholz;J. P. P. Muyrers;A. F. Stewart.
Nature Genetics (1998)

1413 Citations

High-efficiency deleter mice show that FLPe is an alternative to Cre- loxP

Carolyn I. Rodríguez;Frank Buchholz;Jenna Galloway;Reynaldo Sequerra.
Nature Genetics (2000)

1161 Citations

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

Marco Y. Hein;Nina C. Hubner;Ina Poser;Juergen Cox.
Cell (2015)

823 Citations

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.

Ina Poser;Mihail Sarov;Mihail Sarov;James R.A. Hutchins;Jean Karim Hériché.
Nature Methods (2008)

584 Citations

Minimizing the risk of reporting false positives in large-scale RNAi screens

Christophe J Echeverri;Philip A Beachy;Buzz Baum;Michael Boutros.
Nature Methods (2006)

510 Citations

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

James R. A. Hutchins;Yusuke Toyoda;Björn Hegemann;Ina Poser.
Science (2010)

501 Citations

Improved properties of FLP recombinase evolved by cycling mutagenesis.

Buchholz F;Angrand Po;Stewart Af.
Nature Biotechnology (1998)

500 Citations

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I

Christian G Riedel;Vittorio L Katis;Vittorio L Katis;Yuki Katou;Saori Mori.
Nature (2006)

498 Citations

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

Ralf Kittler;Gabriele Putz;Laurence Pelletier;Ina Poser.
Nature (2004)

470 Citations

Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells.

Dun Yang;Frank Buchholz;Zhongdong Huang;Andrei Goga.
Proceedings of the National Academy of Sciences of the United States of America (2002)

449 Citations

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