Frank Buchholz mostly deals with Genetics, RNA interference, Gene, Cell biology and Gene silencing. Genetics and Computational biology are frequently intertwined in his study. His RNA interference research integrates issues from False positive paradox and Bioinformatics.
The study incorporates disciplines such as Mitosis and Viral replication in addition to Gene. The Cell biology study which covers Gene expression profiling that intersects with Stem cell, Embryonic stem cell and Chromatin immunoprecipitation. His Gene silencing study combines topics from a wide range of disciplines, such as RNA and Small interfering RNA.
His scientific interests lie mostly in Cell biology, Genetics, RNA interference, Recombinase and Computational biology. Frank Buchholz combines subjects such as Embryonic stem cell, Cell, Cell division and Molecular biology with his study of Cell biology. His studies in Molecular biology integrate themes in fields like Gene expression, Transgene and Fusion protein.
His biological study spans a wide range of topics, including Gene silencing, Gene knockdown and Small interfering RNA. His work deals with themes such as Virology, Genome, Long terminal repeat, Provirus and DNA, which intersect with Recombinase. His Computational biology research includes elements of Genome editing, Rna protein and Functional genomics.
His primary scientific interests are in Cell biology, Internal medicine, Oncology, Gene and Recombinase. His work carried out in the field of Cell biology brings together such families of science as Embryonic stem cell, RNA interference, Cell culture and DNA damage. Many of his research projects under Internal medicine are closely connected to Head and neck squamous-cell carcinoma with Head and neck squamous-cell carcinoma, tying the diverse disciplines of science together.
His work on Cell cycle and Enhancer as part of general Gene research is frequently linked to Context, bridging the gap between disciplines. He has researched Recombinase in several fields, including Genome editing, Genome, Genome engineering, DNA and Computational biology. Genome is a subfield of Genetics that Frank Buchholz tackles.
Frank Buchholz spends much of his time researching Cell biology, DNA, Genetics, Retrospective cohort study and Oncology. His research integrates issues of Spindle apparatus, Cell division, Embryonic stem cell and Cell polarity in his study of Cell biology. His DNA study integrates concerns from other disciplines, such as Recombinase and Genome.
He integrates Genetics with CST complex in his research. The concepts of his Retrospective cohort study study are interwoven with issues in Cancer stem cell, Cancer and CD44. Frank Buchholz interconnects Clinical endpoint, Proportional hazards model and Pathology in the investigation of issues within Oncology.
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A new logic for DNA engineering using recombination in Escherichia coli
Youming Zhang;F. Buchholz;J. P. P. Muyrers;A. F. Stewart.
Nature Genetics (1998)
High-efficiency deleter mice show that FLPe is an alternative to Cre- loxP
Carolyn I. Rodríguez;Frank Buchholz;Jenna Galloway;Reynaldo Sequerra.
Nature Genetics (2000)
A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances
Marco Y. Hein;Nina C. Hubner;Ina Poser;Juergen Cox.
Cell (2015)
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.
Ina Poser;Mihail Sarov;Mihail Sarov;James R.A. Hutchins;Jean Karim Hériché.
Nature Methods (2008)
Minimizing the risk of reporting false positives in large-scale RNAi screens
Christophe J Echeverri;Philip A Beachy;Buzz Baum;Michael Boutros.
Nature Methods (2006)
Systematic analysis of human protein complexes identifies chromosome segregation proteins.
James R. A. Hutchins;Yusuke Toyoda;Björn Hegemann;Ina Poser.
Science (2010)
Improved properties of FLP recombinase evolved by cycling mutagenesis.
Buchholz F;Angrand Po;Stewart Af.
Nature Biotechnology (1998)
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I
Christian G Riedel;Vittorio L Katis;Vittorio L Katis;Yuki Katou;Saori Mori.
Nature (2006)
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
Ralf Kittler;Gabriele Putz;Laurence Pelletier;Ina Poser.
Nature (2004)
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells.
Dun Yang;Frank Buchholz;Zhongdong Huang;Andrei Goga.
Proceedings of the National Academy of Sciences of the United States of America (2002)
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