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Molecular Biology

D-Index
50
Citations
13843
World Ranking
2537
National Ranking
80

Overview

Laurence Pelletier is a researcher affiliated with the Lunenfeld-Tanenbaum Research Institute in Canada. Their scientific work spans multiple disciplines primarily within biochemistry, genetics, and molecular biology, contributing extensively to both foundational and applied biomedical research.

Their main research fields include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these areas, Pelletier has delved into several specialized subfields, such as:

  • Molecular Biology
  • Cell Biology
  • Infectious Diseases
  • Genetics
  • Computer Vision and Pattern Recognition

Their research topics cover a diverse set of themes, including:

  • Microtubule and mitosis dynamics
  • SARS-CoV-2 detection and testing
  • SARS-CoV-2 and COVID-19 Research
  • CRISPR and Genetic Engineering
  • Genetic and Kidney Cyst Diseases
  • Ubiquitin and proteasome pathways
  • Image and Signal Denoising Methods

Pelletier's scholarly output features publications in several key scientific venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Journal of Cell Science
  • Nature Communications
  • Zenodo (CERN European Organization for Nuclear Research)

Among the recent publications are:

  • A proximity-dependent biotinylation map of a human cell, 2021, Nature
  • Saturation variant interpretation using CRISPR prime editing, 2022, Nature Biotechnology
  • Centriolar satellite biogenesis and function in vertebrate cells, 2020, Journal of Cell Science
  • A fast blind zero-shot denoiser, 2022, Nature Machine Intelligence
  • Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis, 2023, eLife

Pelletier has collaborated frequently with a network of researchers that includes Suzanna L. Prosser, Reuben Philip, Amit Sharma, Johnny M. Tkach, and Jeffrey L. Wrana. This reflects a strongly interdisciplinary approach combining expertise from multiple complementary domains.

Best Publications

  • Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase

    Nadine K. Kolas;J. Ross Chapman;Shinichiro Nakada;Jarkko Ylanko;Jarkko Ylanko

  • The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

    Grant S. Stewart;Stephanie Panier;Stephanie Panier;Kelly Townsend;Abdallah K. Al-Hakim

  • BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.

    Ina Poser;Mihail Sarov;Mihail Sarov;James R.A. Hutchins;Jean Karim Hériché

  • Systematic analysis of human protein complexes identifies chromosome segregation proteins.

    James R. A. Hutchins;Yusuke Toyoda;Björn Hegemann;Ina Poser

  • Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I

    Christian G Riedel;Vittorio L Katis;Vittorio L Katis;Yuki Katou;Saori Mori

  • A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.

    Gagan D. Gupta;Étienne Coyaud;João Gonçalves;Bahareh A. Mojarad

  • An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

    Ralf Kittler;Gabriele Putz;Laurence Pelletier;Ina Poser

  • Centriole assembly in Caenorhabditis elegans

    Laurence Pelletier;Eileen O'Toole;Anne Schwager;Anthony A Hyman

  • Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material

    Steffen Lawo;Steffen Lawo;Monica Hasegan;Gagan D. Gupta;Laurence Pelletier;Laurence Pelletier

  • Mitotic spindle assembly in animal cells: a fine balancing act

    Suzanna L. Prosser;Laurence Pelletier;Laurence Pelletier

  • Genome-scale RNAi profiling of cell division in human tissue culture cells

    Ralf Kittler;Laurence Pelletier;Laurence Pelletier;Anne Kristine Heninger;Mikolaj Slabicki

  • A proximity-dependent biotinylation map of a human cell.

    Christopher D. Go;Christopher D. Go;James D. R. Knight;Archita Rajasekharan;Bhavisha Rathod

  • Centriole assembly requires both centriolar and pericentriolar material proteins.

    Alexander Dammermann;Thomas Müller-Reichert;Laurence Pelletier;Bianca Habermann

  • A strategy for modulation of enzymes in the ubiquitin system.

    Andreas Ernst;George Avvakumov;Jiefei Tong;Yihui Fan

  • Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis

    Kazuhisa Kinoshita;Tim L. Noetzel;Laurence Pelletier;Karl Mechtler

  • The Caenorhabditis elegans Centrosomal Protein SPD-2 Is Required for both Pericentriolar Material Recruitment and Centriole Duplication

    Laurence Pelletier;Nurhan Özlü;Eva Hannak;Carrie Cowan

  • HAUS, the 8-Subunit Human Augmin Complex, Regulates Centrosome and Spindle Integrity

    Steffen Lawo;Steffen Lawo;Mikhail Bashkurov;Michael Mullin;Mariana Gomez Ferreria

  • The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains

    Heike Fölsch;Marc Pypaert;Sandra Maday;Laurence Pelletier

  • Golgin tethers define subpopulations of COPI vesicles.

    Jörg Malsam;Ayano Satoh;Laurence Pelletier;Graham Warren

  • Golgi biogenesis in Toxoplasma gondii

    Laurence Pelletier;Charlene A. Stern;Marc Pypaert;David Sheff

Frequent Co-Authors

Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Brian Raught
Brian Raught Princess Margaret Cancer Centre
Daniel Durocher
Daniel Durocher Lunenfeld-Tanenbaum Research Institute
Anthony A. Hyman
Anthony A. Hyman Max Planck Institute of Molecular Cell Biology and Genetics
Jeffrey L. Wrana
Jeffrey L. Wrana Lunenfeld-Tanenbaum Research Institute
Rod Bremner
Rod Bremner Lunenfeld-Tanenbaum Research Institute
Frank Buchholz
Frank Buchholz TU Dresden
Joel Pearson
Joel Pearson University of New South Wales
Tony Mazzulli
Tony Mazzulli University Health Network
Ina Poser
Ina Poser Max Planck Society

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