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Molecular Biology

D-Index
42
Citations
6793
World Ranking
3025
National Ranking
90

Overview

Rod Bremner is affiliated with the Lunenfeld-Tanenbaum Research Institute in Canada. Their research spans multiple disciplines, primarily within biochemistry, genetics, molecular biology, and medicine. They have made contributions to both fundamental and applied areas in the biomedical sciences.

The scientist's work is marked by publications in various fields, including molecular biology, infectious diseases, oncology, biomedical engineering, and cellular and molecular neuroscience.

Key topics addressed in their research include:

  • SARS-CoV-2 detection and testing
  • Retinal Development and Disorders
  • Cancer-related Molecular Pathways
  • SARS-CoV-2 and COVID-19 Research
  • Biosensors and Analytical Detection
  • Hippo pathway signaling and YAP/TAZ
  • Cancer Genomics and Diagnostics

Frequent co-authors collaborating with Rod Bremner have included:

  • Joel D. Pearson
  • Suying Lü
  • Jeffrey L. Wrana
  • Daniel Trcka

Their research appears regularly in several scientific journals. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Communications
  • The EMBO Journal
  • PLoS ONE

Recent publications of note include:

  • Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development (2020, Developmental Cell)
  • Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity (2021, Cancer Cell)
  • CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities (2022, Cell Reports)
  • A glucose meter interface for point-of-care gene circuit-based diagnostics (2021, Nature Communications)
  • Photoreceptor nanotubes mediate the in vivo exchange of intracellular material (2021, The EMBO Journal)

Best Publications

  • Genetic changes in skin tumor progression: correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7.

    R. Bremner;A. Balmain

  • VSX1: A gene for posterior polymorphous dystrophy and keratoconus

    Elise Héon;Alex Greenberg;Kelly K. Kopp;David Rootman

  • Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma.

    Danian Chen;Izhar Livne-bar;Jackie L Vanderluit;Ruth S Slack

  • Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development

    Yufeng Lu;Fion Shiau;Wenyang Yi;Suying Lu

  • E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.

    Jean Leon Chong;Pamela L. Wenzel;M. Teresa Sáenz-Robles;Vivek Nair;Vivek Nair

  • Direct transcriptional repression by pRB and its reversal by specific cyclins.

    R Bremner;B L Cohen;M Sopta;P A Hamel

  • Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice.

    Burns Pa;Kemp Cj;Gannon Jv;Lane Dp

  • Involvement of Retinoblastoma Family Members and E2F/DP Complexes in the Death of Neurons Evoked by DNA Damage

    David S. Park;David S. Park;Erick J. Morris;Rod Bremner;Elizabeth Keramaris

  • The search for the retinoblastoma cell of origin

    Michael A. Dyer;Rod Bremner;Rod Bremner

  • Division and apoptosis of E2f-deficient retinal progenitors

    Danian Chen;Marek Pacal;Pamela Wenzel;Paul S. Knoepfler

  • Retinoblastoma: the disease, gene and protein provide critical leads to understand cancer

    David DiCiommo;Brenda L. Gallie;Rod Bremner

  • Rapid, High Level Protein Production Using DNA-based Semliki Forest Virus Vectors

    David P. DiCiommo;Rod Bremner

  • Chx10 is required to block photoreceptor differentiation but is dispensable for progenitor proliferation in the postnatal retina

    Izzy Livne-bar;Marek Pacal;Melissa C. Cheung;Mark Hankin

  • Interferon‐γ‐induced chromatin remodeling at the CIITA locus is BRG1 dependent

    Samantha G. Pattenden;Robert Klose;Elizabeth Karaskov;Rod Bremner

  • A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity.

    E Zacksenhaus;R Bremner;R A Phillips;B L Gallie

  • CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome

    Lawrence E. Heisler;Dax Torti;Paul C. Boutros;John Watson

  • The chromatin-remodeling enzyme BRG1 coordinates CIITA induction through many interdependent distal enhancers

    Zuyao Ni;Mohamed Abou El Hassan;Zhaodong Xu;Tao Yu

  • Deletion of RB exons 24 and 25 causes low-penetrance retinoblastoma.

    Rod Bremner;Daisy Chan Du;Mary J. Connolly-Wilson;Peter Bridge

  • Apical role for BRG1 in cytokine-induced promoter assembly.

    Zuyao Ni;Elizabeth Karaskov;Tao Yu;Steven M. Callaghan

  • VSX1: A gene for Posterior Polymorphous Dystrophy and Keratoconus

    E Heon;KK Kopp;R Bremner;D Rootman

Frequent Co-Authors

Joel Pearson
Joel Pearson University of New South Wales
Laurence Pelletier
Laurence Pelletier Lunenfeld-Tanenbaum Research Institute
Tony Mazzulli
Tony Mazzulli University Health Network
Jeffrey L. Wrana
Jeffrey L. Wrana Lunenfeld-Tanenbaum Research Institute
Gustavo Leone
Gustavo Leone Medical University of South Carolina
Allan Balmain
Allan Balmain University of California, San Francisco
Liliana Attisano
Liliana Attisano University of Toronto
Brenda L. Gallie
Brenda L. Gallie University of Toronto
Helen McNeill
Helen McNeill Washington University in St. Louis
Loyal A. Goff
Loyal A. Goff Johns Hopkins University School of Medicine

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