His research combines Bone remodeling and Endocrinology. His Bone remodeling study frequently draws connections between adjacent fields such as Endocrinology. His Internal medicine study frequently links to related topics such as Hypothalamus. His study connects Internal medicine and Hypothalamus. Naoto Kubota applies his multidisciplinary studies on Insulin resistance and Diabetes mellitus in his research. He performs integrative Diabetes mellitus and Type 2 diabetes research in his work. He connects Type 2 diabetes with Insulin in his study. His Insulin study typically links adjacent topics like Adipokine. In his works, Naoto Kubota undertakes multidisciplinary study on Adipokine and Adiponectin.
His research combines Obesity and Endocrinology. Naoto Kubota merges Obesity with Insulin resistance in his study. His research links IRS2 with Insulin resistance. In his works, Naoto Kubota undertakes multidisciplinary study on IRS2 and Insulin receptor. Insulin receptor connects with themes related to Insulin in his study. His Adiponectin research extends to Insulin, which is thematically connected. His work on Endocrinology expands to the thematically related Adiponectin. As part of his studies on Internal medicine, he frequently links adjacent subjects like Peroxisome proliferator-activated receptor. His work on Internal medicine expands to the thematically related Peroxisome proliferator-activated receptor.
Cohort study is intertwined with Cohort and Prospective cohort study in his research. Borrowing concepts from Cohort study, Naoto Kubota weaves in ideas under Cohort. His study on Internal medicine is mostly dedicated to connecting different topics, such as Confidence interval. Confidence interval is frequently linked to Internal medicine in his study. Endocrinology is often connected to Lipid metabolism in his work. His Endocrinology research extends to the thematically linked field of Lipid metabolism. Naoto Kubota integrates several fields in his works, including Pathology and Immunohistochemistry. In his works, Naoto Kubota undertakes multidisciplinary study on Immunohistochemistry and Pathology. His work blends Disease and Gene studies together.
His research ties Postprandial and Internal medicine together. His research brings together the fields of Insulin and Postprandial. His research is interdisciplinary, bridging the disciplines of IRS1 and Insulin. He merges IRS1 with Insulin receptor in his study. Naoto Kubota merges Insulin receptor with GLUT4 in his research. His research on GLUT4 often connects related topics like Internal medicine. Naoto Kubota performs multidisciplinary study in the fields of Endocrinology and Physiology via his papers. He undertakes interdisciplinary study in the fields of Physiology and Endocrinology through his works. Naoto Kubota combines Insulin resistance and Adipose tissue in his research.
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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
T. Yamauchi;J. Kamon;H. Waki;Y. Terauchi.
Nature Medicine (2001)
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
Takashi Kadowaki;Toshimasa Yamauchi;Naoto Kubota;Kazuo Hara.
Journal of Clinical Investigation (2006)
Disruption of adiponectin causes insulin resistance and neointimal formation.
Naoto Kubota;Yasuo Terauchi;Toshimasa Yamauchi;Tetsuya Kubota.
Journal of Biological Chemistry (2002)
PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance
Naoto Kubota;Yasuo Terauchi;Hiroshi Miki;Hiroyuki Tamemoto;Hiroyuki Tamemoto.
Molecular Cell (1999)
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.
Toshimasa Yamauchi;Yasunori Nio;Toshiyuki Maki;Masaki Kobayashi.
Nature Medicine (2007)
Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance
Nozomu Kamei;Kazuyuki Tobe;Ryo Suzuki;Mitsuru Ohsugi.
Journal of Biological Chemistry (2006)
PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
Toru Akune;Shinsuke Ohba;Satoru Kamekura;Masayuki Yamaguchi.
Journal of Clinical Investigation (2004)
Adiponectin Stimulates AMP-Activated Protein Kinase in the Hypothalamus and Increases Food Intake
Naoto Kubota;Wataru Yano;Tetsuya Kubota;Tetsuya Kubota;Toshimasa Yamauchi.
Cell Metabolism (2007)
Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.
Masato Iwabu;Toshimasa Yamauchi;Miki Okada-Iwabu;Koji Sato.
Nature (2010)
The Mechanisms by Which Both Heterozygous Peroxisome Proliferator-activated Receptor γ (PPARγ) Deficiency and PPARγ Agonist Improve Insulin Resistance
Toshimasa Yamauchi;Junji Kamon;Hironori Waki;Koji Murakami.
Journal of Biological Chemistry (2001)
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