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Molecular Biology

D-Index
61
Citations
14529
World Ranking
1902
National Ranking
945

Research.com Recognitions

  • 2016 - Fellow, National Academy of Inventors

Overview

Francis Barany is affiliated with Cornell University in the United States and has contributed to the field of Biochemistry, Genetics and Molecular Biology through a substantial body of work. Their research spans primarily molecular biology alongside related subfields such as biomedical engineering, cancer research, organic chemistry, and oncology.

The scientist's recent publications include:

  • Novel, Self-Assembling Dimeric Inhibitors of Human β Tryptase, 2020, Journal of Medicinal Chemistry
  • Reversible Assembly of Proteolysis Targeting Chimeras, 2023, ACS Chemical Biology
  • BindingDB Entry 50007648: Novel, Self-Assembling Dimeric Inhibitors of Human β Tryptase, 2021, PubMed
  • Prediction of blood-based biomarkers and subsequent design of bisulfite PCR-LDR-qPCR assay for breast cancer detection, 2020, BMC Cancer
  • Single-molecule detection of cancer mutations using a novel PCR-LDR-qPCR assay, 2020, Human Mutation

Key research topics addressed by Barany include:

  • Protein Degradation and Inhibitors
  • Epigenetics and DNA Methylation
  • Cancer Genomics and Diagnostics
  • Ubiquitin and proteasome pathways
  • Peptidase Inhibition and Analysis
  • RNA modifications and cancer
  • Histone Deacetylase Inhibitors Research

Frequent co-authors who have collaborated with Barany across multiple publications are:

  • Sarah F. Giardina
  • Manny D. Bacolod
  • Steven A. Soper
  • Philip B. Feinberg
  • Elena Valdambrini

In terms of dissemination, Barany has published repeatedly in journals such as:

  • Journal of Medicinal Chemistry
  • Current Cancer Drug Targets
  • UNC Libraries
  • ACS Chemical Biology
  • BMC Cancer

Their work has been recognized by their induction as a Fellow of the National Academy of Inventors in 2016.

Best Publications

  • Genetic disease detection and DNA amplification using cloned thermostable ligase

    Francis Barany

  • Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease

    Francis Barany;John Zebala;Deborah Nickerson;Robert J. Kaiser

  • Detection of nucleic acid sequence differences using coupled polymerase chain reactions

    Francis Barany;Matthew Lubin;George Barany;Robert P. Hammer

  • The ligase chain reaction in a PCR world.

    F Barany

  • Universal DNA microarray method for multiplex detection of low abundance point mutations.

    Norman P Gerry;Nancy E Witowski;Joseph Day;Robert P Hammer

  • Detecting Colorectal Cancer in Stool With the Use of Multiple Genetic Targets

    Seung Myung Dong;Giovanni Traverso;Constance M Johnson;Li Geng

  • Detection of nucleic and sequence differences using the ligase detection reaction with addressable arrays

    Francis Barany;George Barany;Robert P. Hammer;Maria Kempe

  • Association of survival and disease progression with chromosomal instability: A genomic exploration of colorectal cancer

    Michal Sheffer;Manny D. Bacolod;Or Zuk;Sarah F. Giardina

  • Improving the fidelity of Thermus thermophilus DNA ligase

    Jianying Luo;Donald E. Bergstrom;Francis Barany

  • Ligase chain reaction (LCR)--overview and applications.

    M Wiedmann;W J Wilson;J Czajka;J Luo

  • Relationship of gene expression and chromosomal abnormalities in colorectal cancer.

    Dafna Tsafrir;Manny Bacolod;Zachariah Selvanayagam;Ilan Tsafrir

  • Single nucleotide polymorphism seeking long term association with complex disease

    Brian W. Kirk;Matthew Feinsod;Reyna Favis;Richard M. Kliman

  • Expression of L1-CAM and ADAM10 in Human Colon Cancer Cells Induces Metastasis

    Nancy Gavert;Michal Sheffer;Shani Raveh;Simone Spaderna

  • Universal DNA array detection of small insertions and deletions in BRCA1 and BRCA2

    Reyna Favis;Joseph P. Day;Norman P. Gerry;Catherine Phelan

  • Approaching real-time molecular diagnostics: Single-pair fluorescence resonance energy transfer (spFRET) detection for the analysis of low abundant point mutations in K-ras oncogenes

    Musundi B. Wabuyele;Hannah Farquar;Wieslaw Stryjewski;Robert P. Hammer

  • The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability

    Michael Overholtzer;Michael Overholtzer;Pulivarthi H. Rao;Reyna Favis;Xin Yan Lu

  • c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases ☆

    Zhao-Shi Zeng;Martin R. Weiser;Eleanor Kuntz;Chin-Tung Chen

  • Single-stranded hexameric linkers: a system for in-phase insertion mutagenesis and protein engineering.

    Francis Barany

  • High-throughput selection, enumeration, electrokinetic manipulation, and molecular profiling of low-abundance circulating tumor cells using a microfluidic system.

    Udara Dharmasiri;Samuel K Njoroge;Małgorzata A Witek;Morayo G Adebiyi

  • Microarrays assembled in microfluidic chips fabricated from poly(methyl methacrylate) for the detection of low-abundant DNA mutations.

    Yun Wang;Bikas Vaidya;Hannah D. Farquar;Wieslaw Stryjewski

Frequent Co-Authors

Philip B. Paty
Philip B. Paty Memorial Sloan Kettering Cancer Center
Steven A. Soper
Steven A. Soper University of Kansas
Carl A. Batt
Carl A. Batt Cornell University
Martin Wiedmann
Martin Wiedmann Cornell University
Jinru Shia
Jinru Shia Memorial Sloan Kettering Cancer Center
William L. Gerald
William L. Gerald Memorial Sloan Kettering Cancer Center
Jurg Ott
Jurg Ott Rockefeller University
George Barany
George Barany University of Minnesota
Paul B. Fisher
Paul B. Fisher Virginia Commonwealth University
Thierry Soussi
Thierry Soussi Université Paris Cité

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