D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 72 Citations 23,806 235 World Ranking 809 National Ranking 14

Research.com Recognitions

Awards & Achievements

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary scientific interests are in Molecular biology, DNA, Oligonucleotide, Genetics and Cell biology. Ulf Landegren combines subjects such as Nucleic acid sequence, Biochemistry, DNA nanoball sequencing, DNA ligase and Proximity ligation assay with his study of Molecular biology. His studies in DNA integrate themes in fields like Nucleic acid and Ligation.

He interconnects Transcription factor, Aptamer and Target protein in the investigation of issues within Ligation. His Oligonucleotide research incorporates themes from Primer dimer, Rapid amplification of cDNA ends, Rolling circle replication, Computational biology and DNA sequencing. His study in the field of Phosphorylation is also linked to topics like In situ.

His most cited work include:

  • Direct Observation of Individual Endogenous Protein Complexes in Situ by Proximity Ligation (1754 citations)
  • A ligase-mediated gene detection technique (1219 citations)
  • Protein detection using proximity-dependent DNA ligation assays (1086 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Molecular biology, Computational biology, Oligonucleotide, DNA and Proximity ligation assay. When carried out as part of a general Molecular biology research project, his work on Ligation is frequently linked to work in In situ, therefore connecting diverse disciplines of study. His study on Computational biology also encompasses disciplines like

  • Genetics and related Disease,
  • Multiplex that intertwine with fields like Proteomics.

His Oligonucleotide research is multidisciplinary, incorporating perspectives in DNA microarray, Rolling circle replication, Sequencing by ligation, Combinatorial chemistry and DNA sequencing. Within one scientific family, Ulf Landegren focuses on topics pertaining to Nucleic acid under DNA, and may sometimes address concerns connected to Sequence. His research integrates issues of Protein–protein interaction, Cell biology, Antibody and Real-time polymerase chain reaction in his study of Proximity ligation assay.

He most often published in these fields:

  • Molecular biology (32.62%)
  • Computational biology (23.05%)
  • Oligonucleotide (21.63%)

What were the highlights of his more recent work (between 2012-2020)?

  • Proximity ligation assay (18.09%)
  • Molecular biology (32.62%)
  • Computational biology (23.05%)

In recent papers he was focusing on the following fields of study:

Ulf Landegren focuses on Proximity ligation assay, Molecular biology, Computational biology, Multiplex and DNA. His Proximity ligation assay research includes elements of Biomarker, Extracellular vesicles, Disease and Virology. His study in Molecular biology focuses on Ligation in particular.

His studies deal with areas such as Proteome, Drug target and Protein biomarkers as well as Computational biology. The study incorporates disciplines such as Cell, Cell culture, Digital polymerase chain reaction and Cell biology in addition to Multiplex. His study in Oligonucleotide and DNA sequencing falls within the category of DNA.

Between 2012 and 2020, his most popular works were:

  • Flow Cytometric Measurement of Blood Cells With BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia (150 citations)
  • Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors (133 citations)
  • Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells (127 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His primary areas of investigation include Proximity ligation assay, Cell culture, Multiplex, Cell biology and Molecular biology. The Proximity ligation assay study combines topics in areas such as Extracellular vesicles and Ligation. His study in Cell culture is interdisciplinary in nature, drawing from both Cell and Cancer research.

His study ties his expertise on DNA together with the subject of Multiplex. His work carried out in the field of Cell biology brings together such families of science as Transcriptome, Proteomics and Gene isoform. The various areas that Ulf Landegren examines in his Molecular biology study include KLK6, Real-time polymerase chain reaction, Oligonucleotide and Prostasomes.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Direct observation of individual endogenous protein complexes in situ by proximity ligation

Ola Söderberg;Mats Gullberg;Malin Jarvius;Karin Ridderstråle.
Nature Methods (2006)

2369 Citations

A ligase-mediated gene detection technique

Ulf Landegren;Robert Kaiser;Jane Sanders;Leroy Hood.
Science (1988)

1551 Citations

Protein detection using proximity-dependent DNA ligation assays

Simon Fredriksson;Mats Gullberg;Jonas Jarvius;Charlotta Olsson.
Nature Biotechnology (2002)

1461 Citations

Padlock probes: Circularizing oligonucleotides for localized DNA detection

Mats Nilsson;Helena Malmgren;Martina Samiotaki;Marek Kwiatkowski.
Science (1994)

983 Citations

Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens

Ulf Landegren.
Journal of Immunological Methods (1984)

776 Citations

Multiplexed genotyping with sequence-tagged molecular inversion probes

Paul Hardenbol;Johan Banér;Maneesh Jain;Mats Nilsson.
Nature Biotechnology (2003)

724 Citations

Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall.

Per Lindblom;Holger Gerhardt;Stefan Liebner;Alexandra Abramsson.
Genes & Development (2003)

694 Citations

Signal amplification of padlock probes by rolling circle replication

Johan Banér;Mats Nilsson;Maritha Mendel-Hartvig;Ulf Landegren.
Nucleic Acids Research (1998)

643 Citations

Method of detecting a nucleotide change in nucleic acids

Ulf Landegren;Leroy Hood.
(1988)

626 Citations

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

Ola Söderberg;Karl-Johan Leuchowius;Mats Gullberg;Malin Jarvius.
Methods (2008)

569 Citations

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