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Biology and Biochemistry

D-Index
80
Citations
18839
World Ranking
4163
National Ranking
2037

Overview

James P. Simmer is affiliated with the University of Michigan-Ann Arbor in the United States. Their research mainly spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on molecular biology and genetics as subfields. Their scientific contributions include studies in oral surgery and rheumatology as well.

Their work centers on several topics related to dental and oral health, including:

  • Bone and Dental Protein Studies
  • Dental Development and Anomalies
  • Oral and Maxillofacial Pathology
  • Periodontal Regeneration and Treatments
  • Cleft Lip and Palate Research
  • Oral Microbiology and Periodontitis Research
  • Cell Adhesion Molecules Research

Some of the prominent journals where their research has been published include:

  • Scientific Reports
  • Journal of Personalized Medicine
  • International Journal of Molecular Sciences
  • Journal of Dental Research
  • UNC Libraries

Among their recent published papers are:

  • "Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor," 2020, Journal of Biological Chemistry
  • "How Fluoride Protects Dental Enamel from Demineralization," 2020, Journal of International Society of Preventive and Community Dentistry
  • "Analyses of oligodontia phenotypes and genetic etiologies," 2021, International Journal of Oral Science
  • "A genetic model for the secretory stage of dental enamel formation," 2021, Journal of Structural Biology
  • "Alteration of Exon Definition Causes Amelogenesis Imperfecta," 2020, Journal of Dental Research

James P. Simmer collaborates frequently with several researchers, including:

  • Jan C.-C. Hu
  • Jung-Wook Kim
  • Figen Seymen
  • Shih-Kai Wang
  • Mine Koruyucu

Best Publications

  • The structural biology of the developing dental enamel matrix.

    A.G. Fincham;J. Moradian-Oldak;J.P. Simmer

  • Molecular Mechanisms of Dental Enamel Formation

    J.P. Simmer;A.G. Fincham

  • Hereditary Dentin Defects

    J.-W. Kim;J.P. Simmer

  • Proteinases in developing dental enamel.

    J.D. Bartlett;J.P. Simmer

  • Dental enamel formation and its impact on clinical dentistry

    James P. Simmer;Jan C.C. Hu

  • Enamel formation and amelogenesis imperfecta.

    Jan C C Hu;Yong Hee P Chun;Turki Al Hazzazzi;James P. Simmer

  • Functions of KLK4 and MMP-20 in dental enamel formation.

    Yuhe Lu;Petros Papagerakis;Yasuo Yamakoshi;Jan C.-C. Hu

  • MMP-20 mutation in autosomal recessive pigmented hypomaturation amelogenesis imperfecta

    J-W Kim;J P Simmer;T C Hart;P S Hart

  • Self-assembly of a recombinant amelogenin protein generates supramolecular structures.

    A.G. Fincham;J. Moradian-Oldak;J.P. Simmer;P. Sarte

  • Enamelysin (matrix metalloproteinase 20)-deficient mice display an amelogenesis imperfecta phenotype.

    John J. Caterina;Ziedonis Skobe;Joanne Shi;Yanli Ding

  • Identification and Structural and Functional Characterization of Human Enamelysin (MMP-20)†,‡

    Elena Llano;Alberto M. Pendás;Vera Knäuper;Timo Sorsa

  • Investigation of osteocalcin, osteonectin, and dentin sialophosphoprotein in developing human teeth.

    P Papagerakis;A Berdal;M Mesbah;M Peuchmaur

  • Regulation of Dental Enamel Shape and Hardness

    J.P. Simmer;P. Papagerakis;C.E. Smith;D.C. Fisher

  • Expression, structure, and function of enamel proteinases.

    James P. Simmer;Jan C.-C. Hu

  • Molecular cloning and mRNA tissue distribution of a novel matrix metalloproteinase isolated from porcine enamel organ.

    John D. Bartlett;James P. Simmer;Jun Xue;Henry C. Margolis

  • Characterization of Recombinant Pig Enamelysin Activity and Cleavage of Recombinant Pig and Mouse Amelogenins

    O.H. Ryu;A.G. Fincham;C.-C. Hu;C. Zhang

  • The effect of recombinant mouse amelogenins on the formation and organization of hydroxyapatite crystals in vitro

    Elia Beniash;James P. Simmer;Henry C. Margolis

  • Isolation and characterization of a mouse amelogenin expressed in Escherichia coli

    J. P. Simmer;E. C. Lau;C. C. Hu;T. Aoba

  • Purification, characterization and cloning of enamel matrix serine proteinase 1

    J.P. Simmer;M. Fukae;T. Tanabe;Y. Yamakoshi

  • Hierarchical self-assembly of amelogenin and the regulation of biomineralization at the nanoscale

    Ping An Fang;James F. Conway;Henry C. Margolis;James P. Simmer

Frequent Co-Authors

Jan C.-C. Hu
Jan C.-C. Hu University of Michigan–Ann Arbor
John D. Bartlett
John D. Bartlett The Ohio State University
Charles E. Smith
Charles E. Smith McGill University
Malcolm L. Snead
Malcolm L. Snead University of Southern California
Paul H. Krebsbach
Paul H. Krebsbach University of California, Los Angeles
Murim Choi
Murim Choi Seoul National University
Harold C. Slavkin
Harold C. Slavkin University of Southern California
Yoshihiko Yamada
Yoshihiko Yamada National Institutes of Health
Mary MacDougall
Mary MacDougall University of British Columbia
Antonio Nanci
Antonio Nanci University of Montreal

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