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Biology and Biochemistry

D-Index
47
Citations
7355
World Ranking
18751
National Ranking
7658

Overview

Jan C.-C. Hu is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple domains within medicine and biochemistry, genetics, and molecular biology, with a particular focus on dental and bone protein studies and oral health.

The main fields of study associated with their work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broad areas, their subfields of study comprise:

  • Molecular Biology
  • Rheumatology
  • Oral Surgery
  • Urology
  • Genetics

Their research frequently addresses topics such as:

  • Bone and Dental Protein Studies
  • Dental Development and Anomalies
  • Oral and Maxillofacial Pathology
  • Periodontal Regeneration and Treatments
  • Cleft Lip and Palate Research
  • Oral Microbiology and Periodontitis Research
  • Connective Tissue Disorders Research

Jan C.-C. Hu's publication record includes papers published in several journals. The most frequent publication venues are:

  • Scientific Reports
  • Journal of Personalized Medicine
  • International Journal of Molecular Sciences
  • UNC Libraries
  • Journal of Dental Research

Recent notable papers demonstrate the focus of their research on dental and enamel biology. These include:

  • How Fluoride Protects Dental Enamel from Demineralization (2020), Journal of International Society of Preventive and Community Dentistry
  • Analyses of oligodontia phenotypes and genetic etiologies (2021), International Journal of Oral Science
  • A genetic model for the secretory stage of dental enamel formation (2021), Journal of Structural Biology
  • Alteration of Exon Definition Causes Amelogenesis Imperfecta (2020), Journal of Dental Research
  • FAM83H and Autosomal Dominant Hypocalcified Amelogenesis Imperfecta (2020), Journal of Dental Research

Jan C.-C. Hu has collaborated frequently with a number of researchers, including:

  • James P. Simmer
  • Jung-Wook Kim
  • Figen Seymen
  • Mine Koruyucu
  • Shih-Kai Wang

Best Publications

  • Dental enamel formation and its impact on clinical dentistry

    James P. Simmer;Jan C.C. Hu

  • Enamel formation and amelogenesis imperfecta.

    Jan C C Hu;Yong Hee P Chun;Turki Al Hazzazzi;James P. Simmer

  • Functions of KLK4 and MMP-20 in dental enamel formation.

    Yuhe Lu;Petros Papagerakis;Yasuo Yamakoshi;Jan C.-C. Hu

  • MMP-20 mutation in autosomal recessive pigmented hypomaturation amelogenesis imperfecta

    J-W Kim;J P Simmer;T C Hart;P S Hart

  • Expression, structure, and function of enamel proteinases.

    James P. Simmer;Jan C.-C. Hu

  • FAM83H Mutations in Families with Autosomal-Dominant Hypocalcified Amelogenesis Imperfecta

    Jung Wook Kim;Sook Kyung Lee;Zang Hee Lee;Joo Cheol Park

  • Enamel defects and ameloblast-specific expression in Enam knock-out/lacZ knock-in mice

    Jan C.-C. Hu;Yuanyuan Hu;Charles E. Smith;Marc D. McKee

  • Hypomaturation Enamel Defects in Klk4 Knockout/LacZ Knockin Mice

    James P. Simmer;Yuanyuan Hu;Rangsiyakorn Lertlam;Yasuo Yamakoshi

  • A nonsense mutation in the enamelin gene causes local hypoplastic autosomal dominant amelogenesis imperfecta (AIH2)

    Carina K. Mårdh;Birgitta Bäckman;Gösta Holmgren;Jan C.-C. Hu

  • Enamelysin and kallikrein-4 mRNA expression in developing mouse molars.

    Jan C.-C. Hu;Xiaoling Sun;Chuhua Zhang;Shengxi Liu

  • A novel splice acceptor mutation in the DSPP gene causing dentinogenesis imperfecta type II

    J.-W. Kim;J.-W. Kim;S.-H. Nam;K.-T. Jang;S.-H. Lee

  • Dentin Sialophosphoprotein Is Processed by MMP-2 and MMP-20 in Vitro and in Vivo

    Yasuo Yamakoshi;Jan C.-C. Hu;Takanori Iwata;Takanori Iwata;Kazuyuki Kobayashi;Kazuyuki Kobayashi

  • Developmental biology and genetics of dental malformations.

    Jan C C Hu;James P. Simmer

  • Mutational hot spot in the DSPP gene causing dentinogenesis imperfecta type II

    Jung Wook Kim;Jung Wook Kim;Jan C.C. Hu;Jae Il Lee;Sung Kwon Moon

  • Porcine kallikrein-4 activation, glycosylation, activity, and expression in prokaryotic and eukaryotic hosts

    Okhee Ryu;Jan C C Hu;Yasuo Yamakoshi;Yasuo Yamakoshi;Jana L Villemain

  • A comparison of enamelin and amelogenin expression in developing mouse molars.

    Jan C C Hu;Xiaoling Sun;Chuhua Zhang;James P. Simmer

  • Mutational analysis of candidate genes in 24 amelogenesis imperfecta families

    Jung Wook Kim;James P. Simmer;Brent P L Lin;Figen Seymen

  • Human and mouse enamel phenotypes resulting from mutation or altered expression of AMEL, ENAM, MMP20 and KLK4.

    J. Timothy Wright;Thomas C. Hart;P. Suzanne Hart;Darrin Simmons

  • Dentin Glycoprotein: THE PROTEIN IN THE MIDDLE OF THE DENTIN SIALOPHOSPHOPROTEIN CHIMERA *

    Yasuo Yamakoshi;Jan C.-C. Hu;Makoto Fukae;Hengmin Zhang

  • Characterization of the mouse and human PRSS17 genes, their relationship to other serine proteases, and the expression of PRSS17 in developing mouse incisors.

    Jan C.-C Hu;Chuhua Zhang;Xiaoling Sun;Ying Yang

Frequent Co-Authors

James P. Simmer
James P. Simmer University of Michigan–Ann Arbor
Charles E. Smith
Charles E. Smith McGill University
John D. Bartlett
John D. Bartlett The Ohio State University
Murim Choi
Murim Choi Seoul National University
Marc D. McKee
Marc D. McKee McGill University
Paul H. Krebsbach
Paul H. Krebsbach University of California, Los Angeles
Yoshihiko Yamada
Yoshihiko Yamada National Institutes of Health
Thomas L. Saunders
Thomas L. Saunders University of Michigan–Ann Arbor
Adele L. Boskey
Adele L. Boskey Hospital for Special Surgery
David W. McComb
David W. McComb The Ohio State University

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