2026 Michael Boutros: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	86	816	727	66	61	313	33456

Overview

Michael Boutros is a researcher affiliated with the German Cancer Research Center in Germany, with a primary focus in the field of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields including Molecular Biology, Immunology, Oncology, Cell Biology, and Cancer Research.

The scientist has contributed extensively to topics such as:

CRISPR and Genetic Engineering
Wnt/β-catenin signaling in development and cancer
Invertebrate Immune Response Mechanisms
Single-cell and spatial transcriptomics
Neurobiology and Insect Physiology Research
RNA and protein synthesis mechanisms
Insect symbiosis and bacterial influences

Michael Boutros has authored several notable research papers, including:

"SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB," published in 2022 in Communications Biology
"Pooled In Vitro and In Vivo CRISPR-Cas9 Screening Identifies Tumor Suppressors in Human Colon Organoids," published in 2020 in Cell Stem Cell
"A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila," published in 2020 in eLife
"The Organoid Cell Atlas," published in 2020 in Nature Biotechnology
"Inhibition of LTβR signalling activates WNT-induced regeneration in lung," published in 2020 in Nature

The researcher's frequent co-authors include:

Fillip Port
Tianzuo Zhan
Johannes Betge
Florian Heigwer
Séamus J. Martin

Publications by Michael Boutros appear regularly in key scientific venues such as:

bioRxiv (Cold Spring Harbor Laboratory)
FEBS Journal
Zeitschrift für Gastroenterologie
Nature Communications
Developmental Cell

Best Publications

Wnt signaling in cancer.

T. Zhan;N. Rindtorff;Michael Boutros

2428
Citations
A global genetic interaction network maps a wiring diagram of cellular function

Michael Costanzo;Benjamin VanderSluis;Elizabeth N. Koch;Anastasia Baryshnikova

1386
Citations
The Promise and Perils of Wnt Signaling Through β-Catenin

Randall T. Moon;Bruce Bowerman;Michael Boutros;Norbert Perrimon

1286
Citations
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons

Jayhong A Chong;José Tapia-Ramirez;Sandra Kim;Juan J Toledo-Aral

1260
Citations
Active Wnt proteins are secreted on exosomes

Julia Christina Gross;Varun Chaudhary;Kerstin Bartscherer;Michael Boutros

1052
Citations
Dishevelled Activates JNK and Discriminates between JNK Pathways in Planar Polarity and wingless Signaling

Michael Boutros;Nuria Paricio;David I Strutt;Marek Mlodzik

970
Citations
E-CRISP: fast CRISPR target site identification

Florian Heigwer;Grainne Kerr;Michael Boutros

925
Citations
Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells

Michael Boutros;Amy A. Kiger;Susan Armknecht;Susan Armknecht;Kim Kerr;Kim Kerr

884
Citations
EBImage—an R package for image processing with applications to cellular phenotypes

Grégoire Pau;Florian Fuchs;Oleg Sklyar;Michael Boutros

737
Citations
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.

Kerstin Bartscherer;Nadège Pelte;Dierk Ingelfinger;Michael Boutros

656
Citations
LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.

Andrei Glinka;Christine Dolde;Nadine Kirsch;Ya Lin Huang

643
Citations
Requirement of Prorenin Receptor and Vacuolar H+-ATPase–Mediated Acidification for Wnt Signaling

Cristina Maria Cruciat;Bisei Ohkawara;Sergio P. Acebron;Emil Karaulanov

642
Citations
Sequential Activation of Signaling Pathways during Innate Immune Responses in Drosophila

Michael Boutros;Hervé Agaisse;Hervé Agaisse;Norbert Perrimon;Norbert Perrimon

641
Citations
The art and design of genetic screens: RNA interference

Michael Boutros;Julie Ahringer

608
Citations
Signaling Role of Hemocytes in Drosophila JAK/STAT-Dependent Response to Septic Injury

Hervé Agaisse;Ulla Maja Petersen;Michael Boutros;Bernard Mathey-Prevot

582
Citations
Minimizing the risk of reporting false positives in large-scale RNAi screens

Christophe J Echeverri;Philip A Beachy;Buzz Baum;Michael Boutros

576
Citations
Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset

Sung E Choe;Sung E Choe;Michael Boutros;Michael Boutros;Alan D Michelson;Alan D Michelson;George McDonald Church

490
Citations
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing.

Ana Eulalio;Jan Rehwinkel;Mona Stricker;Eric Huntzinger

431
Citations
Analysis of cell-based RNAi screens

Michael Boutros;Lígia P Brás;Lígia P Brás;Wolfgang Huber

381
Citations
Microscopy-Based High-Content Screening

Michael Boutros;Florian Heigwer;Christina Laufer

380
Citations

Frequent Co-Authors

Philipp Beckhove German Cancer Research Center

Norbert Perrimon Harvard University

Wolfgang Huber European Bioinformatics Institute

Christof Niehrs German Cancer Research Center

Marek Mlodzik Icahn School of Medicine at Mount Sinai

Martina U. Muckenthaler Heidelberg University

Aurelio A. Teleman German Cancer Research Center

Hugo A. Katus Heidelberg University

Jean-Marc Reichhart University of Strasbourg

Renato Paro ETH Zurich

External Links

Personal website of Michael Boutros

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