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Immunology

D-Index
62
Citations
14698
World Ranking
3129
National Ranking
213

Overview

Philipp Beckhove is affiliated with the German Cancer Research Center in Germany and has a research focus primarily within the fields of Medicine, Immunology and Microbiology, as well as Biochemistry, Genetics and Molecular Biology. Their work spans several key subfields including Immunology, Oncology, Molecular Biology, Cancer Research, and Pulmonary and Respiratory Medicine.

The main topics covered in Beckhove's research include:

  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • CAR-T cell therapy research
  • Glioma Diagnosis and Treatment
  • Cancer, Hypoxia, and Metabolism

Beckhove has contributed to several recent scientific publications, which include:

  • "Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8," 2022, Science Advances
  • "Intercellular nanotube-mediated mitochondrial transfer enhances T cell metabolic fitness and antitumor efficacy," 2024, Cell
  • "The Role of Translocator Protein TSPO in Hallmarks of Glioblastoma," 2020, Cancers
  • "Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients," 2021, Nature Communications
  • "CAMK1D Triggers Immune Resistance of Human Tumor Cells Refractory to Anti-PD-L1 Treatment," 2020, Cancer Immunology Research

Frequent coauthors with whom Beckhove has collaborated include:

  • Ayse N. Menevse
  • Maria Xydia
  • Tillmann Michels
  • Peter Hau
  • Slava Stamova

Beckhove has published multiple articles in several recurring journals, reflecting areas of sustained investigation. These publication venues are:

  • Cancers
  • Journal for ImmunoTherapy of Cancer
  • Acta Neuropathologica Communications
  • Cancer Research
  • Pulmonology

Best Publications

  • Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy.

    Felix Klug;Hridayesh Prakash;Hridayesh Prakash;Hridayesh Prakash;Peter E. Huber;Tobias Seibel

  • A vaccine targeting mutant IDH1 induces antitumour immunity

    Theresa Schumacher;Lukas Bunse;Stefan Pusch;Felix Sahm

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8 + T cells

    Rafael Carretero;Ibrahim M Sektioglu;Natalio Garbi;Oscar C Salgado

  • Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy

    Niels Halama;Sara Michel;Matthias Kloor;Inka Zoernig

  • Bone marrow as a priming site for T-cell responses to blood-borne antigen

    Markus Feuerer;Philipp Beckhove;Natalio Garbi;Yolanda Mahnke

  • Myeloid Cells and Related Chronic Inflammatory Factors as Novel Predictive Markers in Melanoma Treatment with Ipilimumab.

    Christoffer Gebhardt;Alexandra Sevko;Huanhuan Jiang;Huanhuan Jiang;Ramtin Lichtenberger

  • Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β

    Jennifer Lohr;Thomas Ratliff;Andrea Huppertz;Yingzi Ge

  • Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow

    Markus Feuerer;Philipp Beckhove;Lianhua Bai;Erich Franz Solomayer

  • Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.

    Kathrin Renner;Christina Bruss;Annette Schnell;Gudrun Koehl

  • The significant role of mast cells in cancer

    Khashayarsha Khazaie;Nichole R. Blatner;Mohammad Wasim Khan;Fotini Gounari

  • Antitumor effect of paclitaxel is mediated by inhibition of myeloid-derived suppressor cells and chronic inflammation in the spontaneous melanoma model.

    Alexandra Sevko;Alexandra Sevko;Tillmann Michels;Tillmann Michels;Melissa Vrohlings;Melissa Vrohlings;Ludmila Umansky

  • Metronomic cyclophosphamide treatment in metastasized breast cancer patients: immunological effects and clinical outcome

    Yingzi Ge;Christoph Domschke;Natalija Stoiber;Sarah Schott

  • Antitumor Vaccination of Patients With Glioblastoma Multiforme: A Pilot Study to Assess Feasibility, Safety, and Clinical Benefit

    Hans Herbert Steiner;Matteo Mario Bonsanto;Philipp Beckhove;Michael Brysch

  • Expression of RORγt Marks a Pathogenic Regulatory T Cell Subset in Human Colon Cancer

    Nichole R. Blatner;Mary F. Mulcahy;Kristen L. Dennis;Denise Scholtens

  • Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma

    Andreas Bonertz;Jürgen Weitz;Dong Ho Kim Pietsch;Nuh N. Rahbari

  • Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy

    Valérie Dutoit;Christel Herold-Mende;Norbert Hilf;Oliver Schoor

  • Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry.

    Saskia J. A. M. Santegoets;Eveline M. Dijkgraaf;Alessandra Battaglia;Philipp Beckhove

  • T-Regulatory Cells Shift from a Protective Anti-Inflammatory to a Cancer-Promoting Proinflammatory Phenotype in Polyposis

    Elias Gounaris;Nichole R. Blatner;Kristen Dennis;Fay Magnusson

  • High Frequencies of Functional Tumor-Reactive T Cells in Bone Marrow and Blood of Pancreatic Cancer Patients

    Friedrich H. Schmitz-Winnenthal;Christine Volk;Kaspar Z'graggen;Luis Galindo

  • Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors

    Philipp Beckhove;Markus Feuerer;Mathias Dolenc;Florian Schuetz

  • Tumor infiltrating T lymphocytes in colorectal cancer: Tumor-selective activation and cytotoxic activity in situ.

    Moritz Koch;Philipp Beckhove;Jan op den Winkel;Daniel Autenrieth

  • Enrichment of functional CD8 memory T cells specific for MUC1 in bone marrow of patients with multiple myeloma

    Carmen Choi;Mathias Witzens;Marianna Bucur;Markus Feuerer

  • Elevated chronic inflammatory factors and myeloid-derived suppressor cells indicate poor prognosis in advanced melanoma patients.

    Huanhuan Jiang;Huanhuan Jiang;Huanhuan Jiang;Christoffer Gebhardt;Christoffer Gebhardt;Ludmila Umansky;Philipp Beckhove

Frequent Co-Authors

Volker Schirrmacher
Volker Schirrmacher German Cancer Research Center
Andreas Schneeweiss
Andreas Schneeweiss German Cancer Research Center
Viktor Umansky
Viktor Umansky Heidelberg University
Christel Herold-Mende
Christel Herold-Mende Heidelberg University
Jürgen Weitz
Jürgen Weitz TU Dresden
Michael Boutros
Michael Boutros German Cancer Research Center
Markus W. Büchler
Markus W. Büchler Champalimaud Foundation
Andreas von Deimling
Andreas von Deimling Heidelberg University
Andreas Unterberg
Andreas Unterberg Heidelberg University
Hartmut Goldschmidt
Hartmut Goldschmidt University Hospital Heidelberg

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