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Christian Jacobsen

Christian Jacobsen

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
14360
World Ranking
15428
National Ranking
170

Overview

Christian Jacobsen is affiliated with Aarhus University in Denmark, focusing on research that intersects medicine and computer science. Their work spans significant contributions in the areas of artificial intelligence, radiology, nuclear medicine, and imaging, with notable research in surgery, epidemiology, and statistical and nonlinear physics.

The main topics covered by Jacobsen's research include:

  • Radiopharmaceutical Chemistry and Applications
  • Medical Imaging Techniques and Applications
  • Neuroendocrine Tumor Research Advances
  • Model Reduction and Neural Networks
  • Generative Adversarial Networks and Image Synthesis
  • Computational Physics and Python Applications
  • Esophageal Cancer Research and Treatment

Christian Jacobsen has published multiple papers, with a focus on both methodological advances and applied research. Selected recent publications include:

  • CoCoGen: Physically-Consistent and Conditioned Score-based Generative Models for Forward and Inverse Problems, 2023, arXiv (Cornell University)
  • Enhancing Physical Modeling with Interpretable Physics-Aware Machine Learning, 2024, Deep Blue (University of Michigan)
  • Enhancing Dynamical System Modeling through Interpretable Machine Learning Augmentations: A Case Study in Cathodic Electrophoretic Deposition, 2024, arXiv (Cornell University)
  • Comparison of the Tissue Distribution of a Long-Circulating Glucagon-like Peptide-1 Agonist Determined by Positron Emission Tomography and Quantitative Whole-Body Autoradiography, 2022, ACS Pharmacology & Translational Science
  • Data for: Synthesis and evaluation of 89Zr-labeled and long-lived GLP-1 receptor agonists for PET imaging, 2020, Mendeley Data

The frequent co-authors who have collaborated with Jacobsen include:

  • Karthik Duraisamy
  • Nitin A. Das
  • Sandra Heskamp
  • Magnus Gustafsson
  • Inga Bjørnsdottir

Jacobsen's work is often published in venues such as:

  • arXiv (Cornell University)
  • Foregut The Journal of the American Foregut Society
  • ACS Pharmacology & Translational Science
  • Deep Blue (University of Michigan)
  • Mendeley Data

The research contributions demonstrate a consistent engagement with advanced computational methods applied to medical and physical sciences, including interpretable machine learning approaches and generative models tailored for both forward and inverse problem settings.

Best Publications

  • Identification of the haemoglobin scavenger receptor.

    Mette Kristiansen;Jonas H. Graversen;Christian Jacobsen;Ole Sonne

  • Sortilin is essential for proNGF-induced neuronal cell death

    Anders Nykjaer;Ramee Lee;Kenneth K. Teng;Pernille Jansen;Pernille Jansen

  • An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3

    Anders Nykjaer;Duska Dragun;Diego Walther;Henrik Vorum

  • Identification of the receptor scavenging hemopexin-heme complexes

    Vibeke Hvidberg;Maciej B Maniecki;Maciej B Maniecki;Maciej B Maniecki;Christian Jacobsen;Christian Jacobsen;Christian Jacobsen;Peter Højrup

  • Megalin Knockout Mice as an Animal Model of Low Molecular Weight Proteinuria

    Jörg-Robert Leheste;Boris Rolinski;Henrik Vorum;Jan Hilpert

  • The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake

    Vibeke Hvidberg;Christian Jacobsen;Roland K. Strong;Jack B. Cowland

  • The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.

    Renata Kozyraki;John Fyfe;Mette Kristiansen;Christian Gerdes

  • Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

    Henrik Birn;John C. Fyfe;Christian Jacobsen;Francoise Mounier

  • Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3).

    Anders Nykjaer;John C. Fyfe;Renata Kozyraki;Jörg Robert Leheste

  • Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia

    Renata Kozyraki;John Fyfe;Pierre J. Verroust;Christian Jacobsen

  • Evidence for an Essential Role of Megalin in Transepithelial Transport of Retinol

    Erik Ilsø Christensen;Jan Øivind Moskaug;Henrik Vorum;Christian Jacobsen

  • Megalin deficiency offers protection from renal aminoglycoside accumulation.

    Christian Schmitz;Jan Hilpert;Christian Jacobsen;Christian Boensch

  • Sortilin/Neurotensin Receptor-3 Binds and Mediates Degradation of Lipoprotein Lipase

    Morten Schallburg Nielsen;Christian Jacobsen;G. Olivecrona;Jørgen Gliemann

  • Extracellular superoxide dismutase (EC-SOD) binds to type i collagen and protects against oxidative fragmentation.

    Steen V. Petersen;Tim D. Oury;Louise Ostergaard;Zuzana Valnickova

  • Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding

    C.Munck Petersen;M.S. Nielsen;C. Jacobsen;J. Tauris

  • MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation.

    Søren Egedal Degn;Annette Hansen;Rudi Steffensen;Christian Jacobsen

  • Activation and Functional Characterization of the Mosaic Receptor SorLA/LR11

    Linda Jacobsen;Peder Madsen;Christian Jacobsen;Morten S. Nielsen

  • The Hemopexin and O-Glycosylated Domains Tune Gelatinase B/MMP-9 Bioavailability via Inhibition and Binding to Cargo Receptors

    Philippe E. Van den Steen;Ilse Van Aelst;Vibeke Hvidberg;Helene Piccard

  • Characterization of an Epithelial ∼460-kDa Protein That Facilitates Endocytosis of Intrinsic Factor-Vitamin B12 and Binds Receptor-associated Protein *

    Henrik Birn;Pierre J. Verroust;Ebba Nexø;Henrik Hager

  • The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region.

    Renata Kozyraki;Renata Kozyraki;Renata Kozyraki;Mette Kristiansen;Mette Kristiansen;Mette Kristiansen;Asli Silahtaroglu;Asli Silahtaroglu;Asli Silahtaroglu;Claus Hansen;Claus Hansen;Claus Hansen

Frequent Co-Authors

Søren K. Moestrup
Søren K. Moestrup Aarhus University
Thomas E. Willnow
Thomas E. Willnow Max Delbrück Center for Molecular Medicine
Erik Ilsø Christensen
Erik Ilsø Christensen Aarhus University
Pierre J. Verroust
Pierre J. Verroust Aarhus University
Jørgen Gliemann
Jørgen Gliemann Aarhus University
Anders Nykjaer
Anders Nykjaer Aarhus University
Claus Munck Petersen
Claus Munck Petersen Aarhus University
Peder Madsen
Peder Madsen Aarhus University
Karl Anker Jørgensen
Karl Anker Jørgensen Aarhus University
Niels Tommerup
Niels Tommerup University of Copenhagen

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