World's Best Scientists 2026 revealed!

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Medicine

D-Index
97
Citations
47474
World Ranking
9112
National Ranking
4700

Overview

Elena Aikawa is affiliated with Brigham and Women's Hospital in the United States. Their research spans several domains within medicine and molecular biology, with a particular focus on cardiovascular medicine.

The scientist has contributed extensively to the literature, including recent papers such as:

  • Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy (2021, European Heart Journal)
  • Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles (2022, Cardiovascular Research)
  • Molecular Mechanisms of Vascular Health: Insights From Vascular Aging and Calcification (2022, Arteriosclerosis Thrombosis and Vascular Biology)
  • Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis (2020, Science Advances)
  • Rheumatic Heart Valve Disease Pathophysiology and Underlying Mechanisms (2021, Frontiers in Cardiovascular Medicine)

Their frequent co-authors include:

  • Masanori Aikawa
  • Sasha A. Singh
  • Mark C. Blaser
  • Shiori Kuraoka
  • Sarvesh Chelvanambi

Elena Aikawa regularly publishes in several prominent venues, such as:

  • Frontiers in Cardiovascular Medicine
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Circulation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Circulation Research

Their main research fields include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Among subfields, the scientist's work is concentrated in areas such as:

  • Cardiology and Cardiovascular Medicine
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Surgery
  • Immunology

The principal topics frequently addressed in their research encompass:

  • Cardiac Valve Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Extracellular vesicles in disease
  • Aortic Disease and Treatment Approaches
  • Atherosclerosis and Cardiovascular Diseases
  • Cardiovascular Function and Risk Factors
  • Lipoproteins and Cardiovascular Health

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions

    Matthias Nahrendorf;Filip K. Swirski;Elena Aikawa;Lars Stangenberg

  • Identification of splenic reservoir monocytes and their deployment to inflammatory sites

    Filip K. Swirski;Matthias Nahrendorf;Martin Etzrodt;Martin Etzrodt;Moritz Wildgruber

  • Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

    Filip K. Swirski;Peter Libby;Elena Aikawa;Pilar Alcaide

  • Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

    Hina Kalra;Richard J. Simpson;Hong Ji;Elena Aikawa

  • Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update.

    Nalini M. Rajamannan;Frank J. Evans;Elena Aikawa;K. Jane Grande-Allen

  • Osteogenesis Associates With Inflammation in Early-Stage Atherosclerosis Evaluated by Molecular Imaging In Vivo

    Elena Aikawa;Matthias Nahrendorf;Jose-Luiz Figueiredo;Filip K. Swirski

  • Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

    Matthias Nahrendorf;Hanwen Zhang;Sheena Hembrador;Peter Panizzi

  • Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis

    Matthias Nahrendorf;Farouc A. Jaffer;Kimberly A. Kelly;David E. Sosnovik

  • Inflammation in Atherosclerosis Visualizing Matrix Metalloproteinase Action in Macrophages In Vivo

    Jun-o Deguchi;Masanori Aikawa;Ching-Hsuan Tung;Elena Aikawa

  • Human Semilunar Cardiac Valve Remodeling by Activated Cells From Fetus to Adult Implications for Postnatal Adaptation, Pathology, and Tissue Engineering

    Elena Aikawa;Peter Whittaker;Mark Farber;Karen Mendelson

  • Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease

    Elena Aikawa;Matthias Nahrendorf;David Sosnovik;Vincent M. Lok

  • Endothelial to Mesenchymal Transition in Cardiovascular Disease: JACC State-of-the-Art Review.

    Jason C. Kovacic;Stefanie Dimmeler;Richard P. Harvey;Toren Finkel

  • Macrophage-derived matrix vesicles: an alternative mechanism for microcalcification in atherosclerotic plaques

    Elena Aikawa;Masanori Aikawa;Sophie New;Kevin Croce

  • Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease

    Filip K. Swirski;Filip K. Swirski;Mikael J. Pittet;Moritz F. Kircher;Elena Aikawa

  • Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques

    JD Joshua Hutcheson;Claudia Goettsch;S Sergio Bertazzo;Natalia Maldonado

  • EVpedia: a community web portal for extracellular vesicles research

    Dae-Kyum Kim;Jaewook Lee;Sae Rom Kim;Dong Sic Choi

  • Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase

    Michael O. Breckwoldt;John W. Chen;Lars Stangenberg;Elena Aikawa

  • Mitral valve disease—morphology and mechanisms

    Robert A. Levine;Albert A. Hagége;Daniel P. Judge;Muralidhar Padala

  • Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease

    Elena Aikawa;Masanori Aikawa;Peter Libby;Jose-Luiz Figueiredo

Frequent Co-Authors

Masanori Aikawa
Masanori Aikawa Brigham and Women's Hospital
Ralph Weissleder
Ralph Weissleder Harvard University
Peter Libby
Peter Libby Brigham and Women's Hospital
Matthias Nahrendorf
Matthias Nahrendorf Harvard University
Robert A. Levine
Robert A. Levine Harvard University
Joyce Bischoff
Joyce Bischoff Harvard Medical School
Filip K. Swirski
Filip K. Swirski Icahn School of Medicine at Mount Sinai
Frederick J. Schoen
Frederick J. Schoen Brigham and Women's Hospital
John E. Mayer
John E. Mayer Boston Children's Hospital
Mikael J. Pittet
Mikael J. Pittet University of Geneva

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