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Medicine

D-Index
83
Citations
24604
World Ranking
15638
National Ranking
596

Overview

Leo J. Hofland is affiliated with Erasmus University Rotterdam in the Netherlands. Their research is primarily situated within the field of Medicine, with particular focus on subfields such as Endocrinology, Diabetes and Metabolism, Oncology, Epidemiology, Cancer Research, and Neurology.

The scientist's work covers several main topics, including:

  • Neuroendocrine Tumor Research Advances
  • Pituitary Gland Disorders and Treatments
  • Lung Cancer Research Studies
  • Neuroblastoma Research and Treatments
  • Pancreatic and Hepatic Oncology Research
  • Adrenal and Paraganglionic Tumors
  • Cancer, Hypoxia, and Metabolism

Recent publications by Leo J. Hofland include the following papers:

  • "Epigenetic regulation of somatostatin and somatostatin receptors in neuroendocrine tumors and other types of cancer" (2020), published in Reviews in Endocrine and Metabolic Disorders
  • "T2-signal intensity, SSTR expression, and somatostatin analogs efficacy predict response to pasireotide in acromegaly" (2020), published in European Journal of Endocrinology
  • "Type I interferons in pancreatic cancer and development of new therapeutic approaches" (2020), published in Critical Reviews in Oncology/Hematology
  • "Levoketoconazole, the 2S,4R Enantiomer of Ketoconazole, a New Steroidogenesis Inhibitor for Cushing's Syndrome Treatment" (2021), published in The Journal of Clinical Endocrinology & Metabolism
  • "Critical appraisal of MGMT in digestive NET treated with alkylating agents" (2020), published in Endocrine Related Cancer

Leo J. Hofland has frequently published in venues such as:

  • European Journal of Endocrinology
  • Endocrine Related Cancer
  • Endocrine Abstracts
  • The Journal of Clinical Endocrinology & Metabolism
  • Cancers

Frequent co-authors collaborating with Leo J. Hofland include:

  • Richard A. Feelders
  • Peter M. van Koetsveld
  • Fadime Dogan
  • Johannes Hofland
  • Wouter W. de Herder

Best Publications

  • Somatostatin receptor scintigraphy with [111In-DTPA-d-Phe1]- and [123I-Tyr3]-octreotide: the Rotterdam experience with more than 1000 patients

    E. P. Krenning;D. J. Kwekkeboom;W. H. Bakker;W. A. P. Breeman

  • Treatment of Adrenocorticotropin-Dependent Cushing’s Syndrome: A Consensus Statement

    B.M.K. Biller;Ashley Barry Grossman;P.M. Stewart;Shlomo Melmed

  • The pathophysiological consequences of somatostatin receptor internalization and resistance

    Leo J. Hofland;Steven W. J. Lamberts

  • [111In-DTPA-D-Phe1]-octreotide, a potential radiopharmaceutical for imaging of somatostatin receptor-positive tumors: synthesis, radiolabeling and in vitro validation

    W.H. Bakker;R. Albert;C. Bruns;W.A.P. Breeman

  • Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes

    Carlotta Gauna;Patric J. D. Delhanty;Leo J. Hofland;Joop A. M. J. L. Janssen

  • The Medical Treatment of Cushing’s Disease: Effectiveness of Chronic Treatment with the Dopamine Agonist Cabergoline in Patients Unsuccessfully Treated by Surgery

    Rosario Pivonello;Maria Cristina De Martino;Paolo Cappabianca;Monica De Leo

  • Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity.

    C. Gauna;F. M. Meyler;J. A. M. J. L. Janssen;P. J. D. Delhanty

  • Comparison of 111In-labeled Somatostatin Analogues for Tumor Scintigraphy and Radionuclide Therapy

    de Jong M;Breeman Wa;Bakker Wh;Kooij Pp

  • The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5

    Leo J Hofland;Joost van der Hoek;Richard Feelders;Maarten O van Aken

  • Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease

    Richard A. Feelders;Christiaan de Bruin;Alberto M. Pereira;Johannes A. Romijn

  • Dopamine receptor expression and function in corticotroph pituitary tumors

    Rosario Pivonello;Diego Ferone;Wouter W. de Herder;Johan M. Kros

  • Parallel in vivo and in vitro detection of functional somatostatin receptors in human endocrine pancreatic tumors: consequences with regard to diagnosis, localization, and therapy.

    S. W. J. Lamberts;L. J. Hofland;P. M. Van Koetsveld;J.-C. Reubi

  • Somatostatin receptors in gastroentero-pancreatic neuroendocrine tumours.

    W W de Herder;L J Hofland;A J van der Lely;S W J Lamberts

  • The Novel Somatostatin Analog SOM230 Is a Potent Inhibitor of Hormone Release by Growth Hormone- and Prolactin-Secreting Pituitary Adenomas in Vitro

    Leo J. Hofland;Joost van der Hoek;Peter M. van Koetsveld;Wouter W. de Herder

  • Ghrelin secretion is inhibited by either somatostatin or cortistatin in humans.

    Fabio Broglio;Peter van Koetsveld;Andrea Benso;Cristina Gottero

  • Expression of somatostatin, cortistatin, and somatostatin receptors in human monocytes, macrophages, and dendritic cells

    Virgil A. S. H. Dalm;P. Martin van Hagen;Peter M. van Koetsveld;Sam Achilefu

  • Novel insights in dopamine receptor physiology.

    Rosario Pivonello;Diego Ferone;Gaetano Lombardi;Annamaria Colao

  • A single-dose comparison of the acute effects between the new somatostatin analog SOM230 and octreotide in acromegalic patients.

    Joost van der Hoek;Wouter W. de Herder;Richard A. Feelders;Aart-Jan van der Lely

  • Ghrelin drives GH secretion during fasting in man

    Alex F Muller;Steven W J Lamberts;Joop A M J L Janssen;Leo J Hofland

  • The endocrine response to acute ghrelin administration is blunted in patients with anorexia nervosa, a ghrelin hypersecretory state

    F Broglio;L Gianotti;S Destefanis;S Fassino

Frequent Co-Authors

Steven W. J. Lamberts
Steven W. J. Lamberts Erasmus University Rotterdam
Wouter W. de Herder
Wouter W. de Herder Erasmus University Rotterdam
Diego Ferone
Diego Ferone University of Genoa
Casper H.J. van Eijck
Casper H.J. van Eijck Erasmus University Rotterdam
Annamaria Colao
Annamaria Colao University of Naples Federico II
Rosario Pivonello
Rosario Pivonello University of Naples Federico II
Ezio Ghigo
Ezio Ghigo University of Turin
Gaetano Lombardi
Gaetano Lombardi University of Naples Federico II
Eric P. Krenning
Eric P. Krenning Erasmus University Rotterdam
Frank H. de Jong
Frank H. de Jong Erasmus University Rotterdam

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