Neil M. O'Brien-Simpson

Overview

Best Publications

• Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers.

  Shu J. Lam;Neil M O'Brien-Simpson;Namfon Pantarat;Adrian Sulistio

  816
  Citations

• Antibiofouling polymer interfaces: poly(ethylene glycol) and other promising candidates

  Sean Lowe;Neil M. O'Brien-Simpson;Luke A. Connal

  505
  Citations

• Chemically modified and conjugated antimicrobial peptides against superbugs.

  Wenyi Li;Frances Separovic;Neil M O'Brien-Simpson;John D Wade

  398
  Citations

• Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice

  Vladimir Ilievski;Paulina K. Zuchowska;Stefan J. Green;Peter T. Toth

  364
  Citations

• Differential Roles of the Protein Corona in the Cellular Uptake of Nanoporous Polymer Particles by Monocyte and Macrophage Cell Lines

  Yan Yan;Katelyn T. Gause;Marloes M. J. Kamphuis;Ching-Seng Ang

  320
  Citations

• Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids.

  Alicia Rasines Mazo;Stephanie Allison-Logan;Fatemeh Karimi;Fatemeh Karimi;Nicholas Jun-An Chan

  290
  Citations

• Kappacin, a Novel Antibacterial Peptide from Bovine Milk

  Marina Malkoski;Stuart G. Dashper;Neil M. O'Brien-Simpson;Gert H. Talbo

  264
  Citations

• Porphyromonas gingivalis outer membrane vesicles exclusively contain outer membrane and periplasmic proteins and carry a cargo enriched with virulence factors.

  Paul D Veith;Yu-Yen Chen;Dhana G Gorasia;Dina Chen

  213
  Citations

• Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

  Wenyi Li;Julien Tailhades;Neil M. O’Brien-Simpson;Frances Separovic

  212
  Citations

• Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo.

  Jessica D. Cecil;Neil M O'Brien-Simpson;Jason C Lenzo;James A Holden

  203
  Citations

• Porphyromonas gingivalis gingipains: the molecular teeth of a microbial vampire.

  N. M. O'Brien-Simpson;P. D. Veith;S. G. Dashper;E. C. Reynolds

  198
  Citations

• Oral health risk factors for bisphosphonate-associated jaw osteonecrosis.

  Claudine Tsao;Ivan Darby;Peter R. Ebeling;Katrina Walsh

  195
  Citations

• Engineering highly effective antimicrobial selenium nanoparticles through control of particle size.

  Tao Huang;James A Holden;Daniel E Heath;Neil M O'Brien-Simpson

  185
  Citations

• Acute phase protein and cytokine levels in serum and saliva: a comparison of detectable levels and correlations in a depressed and healthy adolescent sample.

  Michelle L Byrne;Neil M O'Brien-Simpson;Eric C Reynolds;Katrina A Walsh

  171
  Citations

• Oral Candida colonization in oral cancer patients and its relationship with traditional risk factors of oral cancer: a matched case-control study.

  Ali D. Alnuaimi;David Wiesenfeld;Neil M. O’Brien-Simpson;Eric C. Reynolds

  160
  Citations

• Role of RgpA, RgpB, and Kgp Proteinases in Virulence of Porphyromonas gingivalis W50 in a Murine Lesion Model

  Neil M. O'Brien-Simpson;Rita A. Paolini;Brigitte Hoffmann;Nada Slakeski

  157
  Citations

• Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles.

  Andrew J. Fleetwood;Man K.S. Lee;William Singleton;Adrian Achuthan

  155
  Citations

• Macrophage Depletion Abates Porphyromonas gingivalis–Induced Alveolar Bone Resorption in Mice

  Roselind S Lam;Neil M O'Brien-Simpson;Jason C Lenzo;James A Holden

  155
  Citations

• An Immune Response Directed to Proteinase and Adhesin Functional Epitopes Protects against Porphyromonas gingivalis-Induced Periodontal Bone Loss

  Neil M. O’Brien-Simpson;Rishi D. Pathirana;Rita A. Paolini;Yu-Yen Chen

  151
  Citations

• Immunization with the RgpA-Kgp proteinase-adhesin complexes of Porphyromonas gingivalis protects against periodontal bone loss in the rat periodontitis model

  P. Sunethra Rajapakse;Neil M. O'Brien-Simpson;Nada Slakeski;Brigitte Hoffmann

  139
  Citations