World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
14943
World Ranking
10172
National Ranking
110

Neuroscience

D-Index
62
Citations
14657
World Ranking
3512
National Ranking
16

Hoon Ryu publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Hoon Ryu sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 191 publications — 59th percentile

59% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

Hoon Ryu D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Hoon Ryu sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 62 D-Index — 64th percentile

64% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Overview

Hoon Ryu is affiliated with the Korea Institute of Science and Technology in South Korea. Their research primarily focuses on neuroscience, medicine, and biochemistry, genetics and molecular biology. A significant portion of their work covers molecular biology, neurology, and cellular and molecular neuroscience, with important subfields including physiology and biological psychiatry.

The researcher's major scientific topics include neuroinflammation and neurodegeneration mechanisms, Alzheimer's disease research and treatments, and neuroscience and neuropharmacology research. Additional areas of focus are tryptophan and brain disorders, mitochondrial function and pathology, amyotrophic lateral sclerosis research, and studies involving S100 proteins and annexins.

Hoon Ryu has published extensively in several scientific venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Research Square (Research Square)
  • Molecular Neurodegeneration
  • Nature Communications

Notable recent papers by Hoon Ryu feature contributions to understanding neurodegenerative diseases such as Alzheimer's and Parkinson's. These include:

  • Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2− production, 2020, Nature Neuroscience
  • Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease, 2020, Current Biology
  • Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer's disease, 2022, Cell Metabolism
  • Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease, 2020, Aging Cell
  • Astrocytes Render Memory Flexible by Releasing D-Serine and Regulating NMDA Receptor Tone in the Hippocampus, 2021, Biological Psychiatry

Throughout their career, Hoon Ryu has collaborated frequently with certain researchers, including Seung Jae Hyeon, C. Justin Lee, Junghee Lee, Uiyeol Park, and Eun Mi Hwang.

Best Publications

  • Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice

    Robert J. Ferrante;James K. Kubilus;Junghee Lee;Hoon Ryu

  • GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

    Seonmi Jo;Seonmi Jo;Oleg Yarishkin;Yu Jin Hwang;Ye Eun Chun

  • Neuroprotective Effects of Phenylbutyrate in the N171-82Q Transgenic Mouse Model of Huntington's Disease

    Gabriella Gardian;Susan E. Browne;Dong Kug Choi;Peter Klivenyi

  • Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin.

    Khalequz Zaman;Hoon Ryu;David Hall;Kevin O'Donovan

  • Sodium phenylbutyrate prolongs survival and regulates expression of anti‐apoptotic genes in transgenic amyotrophic lateral sclerosis mice

    Hoon Ryu;Karen Smith;Sandra I. Camelo;Isabel Carreras

  • Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox.

    Junghee Lee;Hoon Ryu;Robert J. Ferrante;Sidney M. Morris

  • Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration.

    Savita Khanna;Sashwati Roy;Hoon Ryu;Praveen Bahadduri

  • miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model

    Soon-Tae Lee;Kon Chu;Keun-Hwa Jung;Jin Hee Kim

  • ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease

    Hoon Ryu;Junghee Lee;Sean W. Hagerty;Byoung Yul Soh

  • Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis.

    Sandra Camelo;Antonio H. Iglesias;Daehee Hwang;Brice Due

  • Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

    Hoon Ryu;Junghee Lee;Beatrix A. Olofsson;Aziza Mwidau

  • Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons.

    Hoon Ryu;Junghee Lee;Khalequz Zaman;James Kubilis;James Kubilis

  • ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway.

    Takao Ohtsuka;Hoon Ryu;Yohji A. Minamishima;Salvador Macip

  • Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice.

    Edward C. Stack;James K. Kubilus;James K. Kubilus;Karen Smith;Karen Smith;Kerry Cormier;Kerry Cormier

  • Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2-production

    Heejung Chun;Hyeonjoo Im;You Jung Kang;Yunha Kim

  • Ibuprofen reduces Aβ, hyperphosphorylated tau and memory deficits in Alzheimer mice

    Ann C. McKee;Isabel Carreras;Isabel Carreras;Lokman Hossain;Hoon Ryu;Hoon Ryu

  • Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival

    Junghee Lee;Junghee Lee;Chun Hyung Kim;David K. Simon;Lyaylya R. Aminova

  • Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease

    Robert J. Ferrante;Hoon Ryu;Hoon Ryu;James K. Kubilus;James K. Kubilus;Santosh D'Mello

  • SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease.

    Junghee Lee;Junghee Lee;Yunha Kim;Tian Liu;Yu Jin Hwang

  • IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux

    Huikyong Lee;Jee Yeon Noh;Yumin Oh;Youngdoo Kim

  • Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons

    Hoon Ryu;Junghee Lee;Junghee Lee;Soren Impey;Rajiv R. Ratan

Frequent Co-Authors

Junghee Lee
Junghee Lee University of California, Los Angeles
Neil W. Kowall
Neil W. Kowall Boston University
Robert J. Ferrante
Robert J. Ferrante Boston University
Myeong Soo Lee
Myeong Soo Lee Korea University of Science and Technology
Rajiv R. Ratan
Rajiv R. Ratan Cornell University
Hun-Taeg Chung
Hun-Taeg Chung University of Ulsan
Ann C. McKee
Ann C. McKee Boston University
C. Justin Lee
C. Justin Lee Institute for Basic Science
Daesoo Kim
Daesoo Kim Korea Advanced Institute of Science and Technology
Jeong-Sun Seo
Jeong-Sun Seo Seoul National University Bundang Hospital

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