Yijuang Chern

Overview

Best Publications

• Aspects of the general biology of adenosine A2A signaling.

  Bertil B. Fredholm;Yijuang Chern;Rafael Franco;Michail Sitkovsky

  238
  Citations

• A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease

  Han-Yun Hsiao;Yu-Chen Chen;Yu-Chen Chen;Hui-Mei Chen;Pang-Hsien Tu

  227
  Citations

• Galectin-3 is required for the microglia-mediated brain inflammation in a model of Huntington’s disease

  Jian Jing Siew;Jian Jing Siew;Hui Mei Chen;Huan Yuan Chen;Hung Lin Chen

  200
  Citations

• Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease

  Tz Chuen Ju;Tz Chuen Ju;Hui Mei Chen;Jiun Tsai Lin;Ching Pang Chang

  193
  Citations

• CGS21680 attenuates symptoms of Huntington's disease in a transgenic mouse model.

  Szu Yi Chou;Yi Chao Lee;Hui Mei Chen;Ming Chang Chiang;Ming Chang Chiang

  193
  Citations

• Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism

  Wen-Chuan Shen;Huei-Ying Li;Guang-Chao Chen;Yijuang Chern

  161
  Citations

• Protein kinase C inhibits adenylyl cyclase type VI activity during desensitization of the A2a-adenosine receptor-mediated cAMP response.

  Hsing Lin Lai;Te Hsun Yang;Robert O. Messing;Yung Hao Ching

  160
  Citations

• Essential role of cAMP-response element-binding protein activation by A2A adenosine receptors in rescuing the nerve growth factor-induced neurite outgrowth impaired by blockage of the MAPK cascade

  Hsiao-Chun Cheng;Hsiu-Ming Shih;Yijuang Chern

  137
  Citations

• Human Mesenchymal Stem Cells Prolong Survival and Ameliorate Motor Deficit through Trophic Support in Huntington's Disease Mouse Models

  Yuan Ta Lin;Yuan Ta Lin;Yijuang Chern;Che Kun James Shen;Hsin Lan Wen

  135
  Citations

• Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease

  Han-Yun Hsiao;Feng-Lan Chiu;Chiung-Mei Chen;Yih-Ru Wu

  123
  Citations

• Activation of protein kinase A and atypical protein kinase C by A(2A) adenosine receptors antagonizes apoptosis due to serum deprivation in PC12 cells.

  Nai Kuei Huang;Ya Wen Lin;Chuen Lin Huang;Robert O. Messing

  120
  Citations

• Adenosine receptor neurobiology: overview

  Jiang-Fan Chen;Chien-fei Lee;Yijuang Chern

  119
  Citations

• Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.

  Kuan Yu Liu;Yu Chiau Shyu;Brett A. Barbaro;Yuan Ta Lin

  116
  Citations

• Neurovascular abnormalities in humans and mice with Huntington's disease

  Chien-Yuan Lin;Yi-Hua Hsu;Ming-Huang Lin;Tsai-Hui Yang

  114
  Citations

• Dysregulation of C/EBPα by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease

  Ming-Chang Chiang;Hui-Mei Chen;Yi-Hsin Lee;Hao-Hung Chang

  113
  Citations

• Regulation of adenylyl cyclase in the central nervous system.

  Yijuang Chern

  110
  Citations

• Multiple mechanisms for desensitization of A2a adenosine receptor-mediated cAMP elevation in rat pheochromocytoma PC12 cells

  Yijuang Chern;Hsing-Lin Lai;J. C. Fong;Yu Liang

  110
  Citations

• The A2A adenosine receptor rescues the urea cycle deficiency of Huntington's disease by enhancing the activity of the ubiquitin-proteasome system

  Ming Chang Chiang;Ming Chang Chiang;Hui Mei Chen;Hsing Lin Lai;Hsiao Wen Chen

  109
  Citations

• Aberrant astrocytes impair vascular reactivity in Huntington disease.

  Han-Yun Hsiao;Han-Yun Hsiao;Yu-Chen Chen;Yu-Chen Chen;Chien-Hsiang Huang;Chien-Hsiang Huang;Chiao-Chi Chen

  109
  Citations

• PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease.

  Ming-Chang Chiang;Yijuang Chern;Rong-Nan Huang

  108
  Citations