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Leslie M. Thompson

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
40075
World Ranking
3791
National Ranking
1875

Leslie M. Thompson publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Leslie M. Thompson sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 185 publications — 43rd percentile

43% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Leslie M. Thompson D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Leslie M. Thompson sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 81 D-Index — 81st percentile

81% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Leslie M. Thompson is affiliated with the University of California, Irvine, located in the United States. Their research focuses on a range of topics within biochemistry, genetics, molecular biology, medicine, and neuroscience, with a particular emphasis on genetic neurodegenerative diseases, mitochondrial function and pathology, and amyotrophic lateral sclerosis (ALS) research.

Their work is distributed across several key fields of study, including:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Neuroscience

Subfields where they have made contributions include:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Neurology
  • Genetics
  • Physiology

The primary topics addressed in their research encompass:

  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology
  • Amyotrophic Lateral Sclerosis Research
  • RNA Research and Splicing
  • Neurogenetic and Muscular Disorders Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurological disorders and treatments

Leslie M. Thompson has published frequently in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Huntington s Disease
  • Nature Communications
  • Nature Neuroscience
  • Neuron

Notable recent papers include:

  • "TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A", 2022, Nature
  • "Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease", 2020, Nature Communications
  • "Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines", 2022, Nature Neuroscience
  • "An RNA-targeting CRISPR-Cas13d system alleviates disease-related phenotypes in Huntington's disease models", 2022, Nature Neuroscience
  • "Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects", 2023, Neuron

Frequent collaborators in their research include:

  • Ricardo Miramontes
  • Ernest Fraenkel
  • Ryan G. Lim
  • Jie Wu
  • Steven Finkbeiner

Best Publications

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

    Marcy E. MacDonald;Christine M. Ambrose;Mabel P. Duyao;Richard H. Myers

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

    M Shah;N Datson;L Srinidhi;VP Stanton

  • Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia.

    Rita Shiang;Leslie M. Thompson;Ya-Zhen Zhu;Deanna M. Church

  • Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

    Joan S. Steffan;Laszlo Bodai;Judit Pallos;Marnix Poelman

  • The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.

    Joan S. Steffan;Aleksey Kazantsev;Olivera Spasic-Boskovic;Marilee Greenwald

  • Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

    E. Hockly;V.M. Richon;B. Woodman;D.L. Smith

  • Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

    Nancy S. Wexler;Judith Lorimer;Julie Porter;Fidela Gomez

  • SUMO modification of Huntingtin and Huntington's disease pathology

    Joan S. Steffan;Namita Agrawal;Judit Pallos;Erica Rockabrand

  • Therapeutic application of histone deacetylase inhibitors for central nervous system disorders.

    Aleksey G. Kazantsev;Leslie M. Thompson

  • Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Alan E. Renton;Nicola Ticozzi

  • Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3

    Patricia L. Tavormina;Rita Shiang;Leslie M. Thompson;Ya-Zhen Zhu

  • Induced Pluripotent Stem Cells from Patients with Huntington’s Disease : Show CAG Repeat-Expansion-Associated Phenotypes

    Virginia B. Mattis;Soshana P. Svendsen;Allison Ebert;Clive N. Svendsen

  • Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau.

    Kim N. Green;Joan S. Steffan;Hilda Martinez-Coria;Xuemin Sun

  • Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models

    Dagmar E. Ehrnhoefer;Martin Duennwald;Phoebe Markovic;Jennifer L. Wacker

  • The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

    Alexandra B. Keenan;Sherry L. Jenkins;Kathleen M. Jagodnik;Simon Koplev

  • IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

    Leslie Michels Thompson;Charity T. Aiken;Linda S. Kaltenbach;Namita Agrawal

  • SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

    Ruth Luthi-Carter;David M. Taylor;Judit Pallos;Emmanuel Lambert

  • Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice

    Xiaofeng Gu;Xiaofeng Gu;Erin R. Greiner;Erin R. Greiner;Rakesh Mishra;Ravindra Kodali

  • Mutant Huntingtin Disrupts the Nuclear Pore Complex

    Jonathan C. Grima;J. Gavin Daigle;Nicolas Arbez;Kathleen C. Cunningham

  • Genome-Wide Analyses Identify KIF5A as a Novel ALS Gene

    Aude Nicolas;Kevin P. Kenna;Alan E. Renton;Nicola Ticozzi

Frequent Co-Authors

J. Lawrence Marsh
J. Lawrence Marsh University of California, Irvine
Clive N. Svendsen
Clive N. Svendsen Cedars-Sinai Medical Center
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
David E. Housman
David E. Housman MIT
William R. Wilcox
William R. Wilcox Emory University
Ernest Fraenkel
Ernest Fraenkel MIT
Gillian P. Bates
Gillian P. Bates University College London
James F. Gusella
James F. Gusella Harvard University
Paul J. Muchowski
Paul J. Muchowski University of California, San Francisco
Marcy E. MacDonald
Marcy E. MacDonald Harvard University

External Links

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Best Scientists Citing Leslie M. Thompson

Michael R. Hayden

Michael R. Hayden

University of British Columbia

Publications: 258

Marcy E. MacDonald

Marcy E. MacDonald

Harvard University

Publications: 178

Christopher A. Ross

Christopher A. Ross

Johns Hopkins University School of Medicine

Publications: 156

James F. Gusella

James F. Gusella

Harvard University

Publications: 138

Gillian P. Bates

Gillian P. Bates

University College London

Publications: 125

Sarah J. Tabrizi

Sarah J. Tabrizi

University College London

Publications: 118

Raymund A.C. Roos

Raymund A.C. Roos

Leiden University Medical Center

Publications: 97

Anthony J. Hannan

Anthony J. Hannan

Florey Institute of Neuroscience and Mental Health

Publications: 92

Blair R. Leavitt

Blair R. Leavitt

University of British Columbia

Publications: 86

Jane S. Paulsen

Jane S. Paulsen

University of Wisconsin–Madison

Publications: 83

Elena Cattaneo

Elena Cattaneo

University of Milan

Publications: 80

David C. Rubinsztein

David C. Rubinsztein

University of Cambridge

Publications: 74

Marian DiFiglia

Marian DiFiglia

Harvard University

Publications: 74

Robert J. Ferrante

Robert J. Ferrante

Boston University

Publications: 72

Xiao-Jiang Li

Xiao-Jiang Li

Jinan University

Publications: 71

Alexandra Durr

Alexandra Durr

Sorbonne University

Publications: 69

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